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Jordan Yaron

Postdoctoral Research Scholar
Post Doctoral Scholars, TEMPE Campus, Mailcode 6401
Biography

2010, Arizona State University
B.S. Biological Sciences - Genetics, Cell and Developmental Biology, summa cum laude

2015, Arizona State University
Ph.D. Biological Design - Inflammasome biology

Research Interests
  • Inflammation and innate immunity
  • Programmed cell death
  • Cellular ion signaling
Publications
  • Mahon BP, Ambadapadi S, Yaron JR, Lomelino CL, Pinard MA, Keinan S, Kurnikov I, Macaulay C, Zhang L, Reeves W, McFadden G, Tibbetts S, McKenna R, Lucas AR. Crystal Structure of Serp-1, a Myxomavirus-derived Immune Modulating Serpin; Structural Design of Serpin Reactive Center Loop (RCL) Peptides with Improved Therapeutic Function. Biochemistry. Accepted.
  • Al-Ani M*, Ambadapadi S*, Yaron JR*, Zheng D, Fortunel A, Doroton-Guevara M, Liu L, Morshed S, Fricker J, Miles W, McKillop M, Lucas A (2017). Atrial Fibrillation Ablation Increases Inflammation-Chemokine Modulation Suppresses Activation of Leukocytes Isolated after Ablation. Cardiovasc Hematol Disord Drug Targets. In Press.
  • Lucas A, Ambadapadi S, Mahon B, Viswanathan K, Chen H, Liu L, Dai E, Munuswami-Ramanujam G, Kwiecien JM, Yaron JR, Narute PS, McKenna R, Keenan S, Brantly M, McFadden G (2017). The Serpintine Solution. J Clin Exp Cardiolog. 8(1), e150
  • Yaron JR, Rao MY, Gangaraju S, Zhang L, Kong X, Su F, Tian Y, Glenn HL, Meldrum DR (2016). The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux. Biochem Biophys. Res Commun. 472(3), 545-550
  • Oliveira CD, Patel K, Mishra V, Trivedi RN, Noel P, Singh A, Yaron JR, Singh VP (2016). Characterization and Predictive Value of Near Infrared 2-Deoxyglucose Optical Imaging in Severe Acute Pancreatitis. PLoS ONE. 11(2), e0149073
  • Yaron JR, Gangaraju S, Rao MY, Kong X, Zhang L, Su F, Tian Y, Glenn HL, Meldrum DR (2015). K+ regulates Ca2+ to drive inflammasome signaling: dynamic visualization of ion flux in live cells. Cell Death Disease. 6(10), e1954
  • Kong X, Su F, Zhang L, Yaron J, Lee F, Shi Z, Tian Y, Meldrum DR (2015). A Highly Selective Mitochondria-Targeting Fluorescent K+ Sensor. Angew Chem Int Ed Engl. 54(41), 12053-12057
  • Yaron JR, Ziegler CP, Tran TH, Glenn HL, Meldrum DR (2014). A convenient, optimized pipeline for isolation, fluorescence microscopy and molecular analysis of live single cells. Biol Proced Online. 16(9)