Eddie F. Brown has a unique administrative background in that he has worked at the highest administrative levels with federal, state, and tribal governments. He is the former Assistant Secretary of Indian Affairs, United States Department of Interior, Washington, DC (1988-1993). Served as associate dean and the director of the Center for American Indian Studies at the George Warren Brown School of Social Work, Washington University, St. Louis, Missouri (1996- 2004); executive director of the Department of Human Services, Tohono O'odham Nation (1993-1996); director of Arizona Department of Economic Security (1987-1989); and chief of the Division of Social Services, Bureau of Indian Affairs, Washington, D.C. (1984-1986). At Arizona State University, Brown directed American Indian Studies and was co-executive director of ASU's American Indian Policy Institute and was a senior sustainability scientist with the Julie Ann Wrigley Global Institute of Sustainability.
Brown has directed a variety of research and demonstration projects related to the impact of welfare reform on American Indian families and children, mental health assessment of American Indian youth, diabetes prevention in tribal communities, Title IV- E state/tribal agreements, and state ICWA compliance issues, and is nationally recognized for his knowledge and skills in working with tribal governments and community programs. He also served as a member of the U.S. President's Board of Advisors on Tribal Colleges and Universities.
Brown is an enrolled member of the Pascua Yaqui Indian Tribe and affiliated with the Tohono O’odham Nation.