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Hao Yan

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Biodesign Center for Molecular Design & Biomimetics
Center Director & Professor
Faculty, TEMPE Campus, Mailcode 7301
School of Molecular Sciences
Milton D. Glick Distinguished Professor
Faculty, TEMPE Campus, Mailcode 7301
Biography: 

Hao Yan studied chemistry at Shandong University, China. He obtained his PhD in chemistry under Professor N. C. Seeman, New York University in 2001. Following a period as an assistant research professor at Duke University in the Computer Science Department, he joined Arizona State University in 2004 as an assistant professor in Department of Chemistry and Biochemistry (now School of Molecular Sciences). He became a full professor in 2008. He is currently the Milton D. Glick Distinguished Professor in Chemistry and Biochemistry and director of the Center for Molecular Design and Biomimetics in the Biodesign Institute at Arizona State University. The themes of his research are structural DNA nanotechnology and DNA-directed self-assembly.

CV
Binary Data Curriculum Vitae
Education: 
  • Ph.D. Chemistry, New York University 2001
  • B.S. Chemistry, Shandong University, China 1993
Research Website: 
http://yanlab.asu.edu/index.html
Research Interests: 

The theme of our research is to use nature's design rules as inspiration to advance biomedical, energy-related, and other technological innovations through the use of self-assembling molecules and materials. We aim to create intelligent materials with better component controls at the molecular level. Our interdisciplinary team is interested in designing bio-inspired molecular building blocks and programming their higher order assembly into systems that will perform complex functions. Our ultimate goal is to engineer an information guided self-assembling molecular system for the finest possible interactions of molecules in a three-dimensional space. Our current research focuses on structural DNA nanotechnology and DNA directed self-assembly, but in a broader sense we are interested in any science related to molecular design, molecular programming, molecular assembly and molecular systems engineering.

Publications: 
  • J. Li, J.B. Dai, S.X. Jiang, M. Xie, T.T. Zhai, L.J. Guo, S.T. Cao, S. Xing, Z.B. Qu, Y. Zhao, F. Wang, Y. Yang, L. Liu, X.L. Zuo, L.H. Wang, H. Yan, C.H. Fan.  Encoding quantized fluorescence states with fractal DNA frameworks.  Nature Communications (2020).
  • Guangbao Yao, Jiang Li, Qian Li, Xiaoliang Chen, Xiaoguo Liu, Fei Wang, Zhibei Qu, Zhilei Ge, Raghu Pradeep Narayanan, Dewight Williams, Hao Pei, Xiaolei Zuo, Lihua Wang, Hao Yan, Ben L. Feringa, Chunhai Fan.  Programming nanoparticle valence bonds with single-stranded DNA encoders.  Nature Materials (2020).
  • X. Qi, X. Liu, L. Matiski, R.R. Del Villar, T. Yip, F. Zhang, S. Sokalingam, S. Jiang, L. Liu, H. Yan, Y. Chang.  RNA Origami Nanostructures for Potent and Safe Anticancer Immunotherapy.  ACS Nano (2020).
  • S. Dey, A. Beatty, H. Yan.  Biomimetic Transmembrane Signal Transducing DNA Nanosensor for Membrane Enclosed Nucleic Acid Biomarker Detection.  Biophysical Journal (2020).
  • F. Hong, D. Ma, K. Wu, L.A. Mina, R.C. Luiten, Y. Liu, H. Yan, A.A. Green.  Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators.  Cell (2020).
  • X. Jing, F. Zhang, M. Pan, X. Dai, J. Li, L. Wang, X. Liu, H. Yan, C. Fan, Solidifying framework nucleic acids with silica.  Nature Protocols (2019).
  • Z. Zhao, C. Wang, H. Yan, Y. Liu, Soft Robotics Programmed with Double Crosslinking DNA Hydrogels.  Advanced Functional Materials (2019).
  • C. Zhang, Z. Wang, Y. Liu, J. Yang, X. Zhang, Y. Li, L. Pan, Y. Ke, H. Yan.  Nicking-Assisted Reactant Recycle To Implement Entropy-Driven DNA Circuit.  Journal of the American Chemical Society (2019).
  • Y. Zhou, X. Qi, Y. Liu, F. Zhang, H. Yan.  DNA-Nanoscaffold-Assisted Selection of Femtomolar Bivalent Human alpha-Thrombin Aptamers with Potent Anticoagulant Activity.  Chembiochem (2019).
  • C. Su, J.D. Weir, F. Zhang, H. Yan, T. Wu.  ENTRNA: a framework to predict RNA foldability.  BMC Bioinformatics (2019).
  • S. Mandal, X. Zhou, S. Lin, H. Yan, N. Woodbury.  Directed Energy Transfer through DNA-Templated J-Aggregates.  Bioconjugate Chemistry (2019).
  • L. Matiski, X. Qi, X. Liu, R. R. del Villar, F. Zhang, H. Yan, Y. Chang.  RNA origami nanostructures for potent and safe anti-cancer immunotherapy.  Journal of Immunology (2019).
  • Y. Xu, S. Jiang, C.R. Simmons, R.P. Narayanan, F. Zhang, A-M Aziz, H. Yan, N. Stephanopoulos.   Nanoscale Cages from Self-Assembling DNA and Protein Building Blocks.  ACS Nano (2019).
  • J. Li, A. Johnson-Buck, Y. Yang, W. Shih, H. Yan, N. Walter. Exploring the speed limit of toehold exchange with a cartwheeling DNA acrobat. Nature Nanotechnology in press (2018).
  • S. Li, Q. Jiang, S. Liu, Y. Zhang, Y. Tian, C. Song, J. Wang, Y. Zou, G. J. Anderson, J. Han, Y. Chang, Y. Liu, C. Zhang, L. Chen, G. Zhou, G. Nie, H. Yan, B. Ding, Y. Zhao. A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo. Nature Biotechnology (2018).
  • E. Boulais, N. Sawaya, R. Veneziano, A. Andreoni, J. Banal, T. Kondo, S. Mandal, S. Lin, G. Schlau-Cohen, N. Woodbury, H. Yan, A. Aspuru-Guzik, M. Bathe. Programmed coherent coupling in a synthetic DNA-based excitonic circuit. Nature Materals (2018).
  • Y. R. Yang, J. Fu, S. Wootten, X. Qi, M. Liu, H. Yan, Y. Liu*. 2D Enzyme Cascade Network with Efficient Substrate Channeling by Swinging Arms. ChemBioChem (2017).
  • D. Han', X. Qi', C. Myhrvold, B. Wang, M. Dai, S. Jiang, M. Bates, Y. Liu, B. An*, F. Zhang*, H. Yan* and P. Yin*. Single-stranded DNA and RNA Origami. Science (2017).
  • F. Zhang, H. Yan*. DNA self-assembly scaled up. Nature (2017).
  • S. Jiang, F. Hong, H. Hu, H. Yan*, Y. Liu*. Understanding the Elementary Steps in DNA Tile-Based Self-Assembly. ACS Nano (2017).
  • J. Li, A. A. Green, H. Yan, C. Fan. Engineering nucleic acid structures for programmable molecular circuitry and intracellular biocomputation. Nature Chem. (2017).
  • C. Simmons, F. Zhang, T. MacCulloch, N. Fahmi, N. Stephanopoulos, Y. Liu, N. Seeman, H. Yan. Tuning the Cavity Size and Chirality of Self-Assembling 3D DNA Crystals. J. Am. Chem. Soc. (2017).
  • D. Mieritz, X. Li, A. Volosin, M. Liu, H. Yan, N. Walter, D. Seo. Tracking Single DNA Nanodevices in Herarchically Meso-Macroporous Antimony-Doped Tin Oxide Demonstrates Finite Confinement. Langmuir (2017).
  • F. Hong, F. Zhang, Y. Liu*, H. Yan*. DNA Origami: Scaffolds for Creating Higher Order Structures. Chem. Rev. (2017).
  • H. Zhang, A. Carey, K. Jeon, M. Liu, T. Murell, J. Locsin, S. Lin, H. Yan, N. Woodbury, D. Seo. A Highly Stable and Scalable Photosynthetic Reaction Center-Graphene Hybrid Electrode System for Biomimetic Solar Energy Transduction. J. Mater. Chem.  (2017).
  • F. Zhang, F. Hong, H. Yan*. DNA Origami Tiles: Nanoscale Mazes. Nature Nanotechnol. (2017).
  • Y. Dong, Y. Yang, Y. Zhang, D. Wang, X. Wei, S. Banerjee, Y. Liu, Z. Yang, H. Yan*, D. Liu*. Cuboid Vesicles Formed by Frame-guided Assembly on DNA Origami Scaffolds. Angew Chem Int Ed. (2017).
  • A. Andreoni, S. Lin, H. Liu, R. E. Blankenship, H. Yan, N. Woodbury. Orange Carotenoid Protein as a Control Element in an Antenna System based on a DNA Nanostructure. Nano Letters (2017).
  • F. Hong, S. Jiang, T. Wang, Y. Liu*, H. Yan*. 3D Framework DNA origami with Layered Crossovers. Angew Chem Int Ed. (2016).
  • A. Carey, H. Zhang, D. Mieritz, A. Volosin, A. Gardiner, R. Cogdell, H. Yan, D. Seo, S. lin, N. Woodbury*. Photocurrent generation by photosynthetic purple bacterial reaction centers interfaced with a porous antimony-doped tin oxide (ATO) electrode. ACS Appl. Matter. Interfaces (2016).
  • J. Fu*, Y. Yang, S. Dhakal, Z. Zhao, M. Liu, T. Zhang, N. Walter, H. Yan. Assembly of Multi-Enzyme Complexes on DNA Nanostructures. Nature Protocols (2016).
  • C. Simmons, F. Zhang, J. Birktoft, X. Qi, D. Han, Y. Liu, R. Sha, H. Abdallah, C. Hernandez, Y. Ohayon, N. Seeman*, H. Yan*. Construction and Structure Determination of a Three-dimensional DNA Crystal. J. Am. Chem. Soc. (2016).
  • R. Veneziano, S. Ratanalert, K. Zhang, F. Zhang, H. Yan, W. Chiu, M. Bathe*. Designer nanoscale DNA assemblies programmed from the top down. Science (2016).
  • F. Zhang*, S. Jiang, W. Li, A. Hunt, Y. Liu*, H. Yan*. Self-assembly of Complex DNA Tessellations using low symmetry multi-arm DNA tiles. Angew Chem Int Ed. (2016).
  • G. Ke, M. Liu, S. Jiang, X. Qi, Y. R. Yang, S. Wootten, F. Zhang, Z. Zhu, Y. Liu*, C. J. Yang*, H. Yan*. Directional Regulation of Enzyme Pathways via the Control of Substrate Channeling on a DNA Origami Scaffold. Angew Chem Int Ed. (2016).
  • M. Liu, J. Fu, X. Qi, S. Wootten, N. Woodbury, Y. Liu*, H. Yan*. A three-enzyme pathway with an optimized geometric arrangement to facilitate substrate transfer. ChemBioChem (2016).
  • W. Li, F. Zhang, H. Yan*, Y. Liu*. DNA Based Arithmetic Function: Half Adder Based on DNA Strand Displacement. Nanoscale (2016).
  • Z. Zhao, J. Fu, S. Dhakal, A. Johnson-Buck, M. Liu, T. Zhang, N. Woodbury, Y. Liu, N. Walter, H. Yan*. Nano-caged Enzymes with Enhanced Catalytic Activity and Increased Stability against Protease Digestion. Nature Commun. (2016).
  • S. Dhakal, M. R. Adendorff, M. Liu, H. Yan*, M. Bathe*, N. G. Walter*. Rational design of DNA-actuated enzyme nanoreactors guided by single molecule analysis. Nanoscale (2016).
  • C. Zhang, J. Yang, S. Jiang, Y. Liu*, H. Yan*. DNAzyme-based Logic Gate-mediated DNA Self-assembly.  Nano Letters (2016).
  • H. Yan, Y. Zhang. DNA/RNA-Based Nanostructures for Cancer Nanomedicine, Section III: Novel Nanometerials for Diagnosis and Therapy. CaNanoPlan (2015).
  • F. Zhang, S. Jiang, S. Wu, Y. Li, C. Mao, Y. Liu*, H. Yan*. Complex wireframe DNA origami nanostructures with multi-arm junction vertices. Nature Nanotechnol. (2015).
  • Y. Yang, Y. Liu, H. Yan*. DNA nanostructures as programmable biomolecular scaffolds. Bioconjugate Chemistry (2015).
  • J. F. Georges, X. Liu, J. Eschbacher, J. Nichols, M. A. Mooney, A. Joy, R. F. Spetzler, B. G. Feuerstein, M. C. Preu, T. Anderson, H. Yan, P. Nakaji*. Use of a Conformational Switching Aptamer for Rapid and Specific Ex Vivo Identification of Central Nervous System Lymphoma in a Xenograft Model. PloS one (2015).
  • A. Samanta, S. Banerjee, Y. Liu*. DNA nanotechnology for nanophotonic applications. Nanoscale (2015).
  • A. Johnson-Buck, S. Jiang, H. Yan, and N. G. Walter. DNA-Cholesterol Barges as Programmable Membrane-Exploring Agents. ACS Nano (2014).
  • A. Samanta, Y. Zhou, S. Zou, H. Yan, Y. Liu. Fluorescence Quenching of Quantum Dots by Gold Nanoparticles: a Potential Long Range Spectroscopic Ruler. Nano Letters (2014).
  • D. Wang, S. Capehart, S. Pal, M. Liu, L. Zhang, J. Schuck, Y. Liu, H. Yan, M. Francis, J. De Yoreo. Hierarchical Assembly of Plasmonic Nanostructures using Virus Capsid Scaffolds on DNA Origami Templates. ACS Nano (2014).
  • F. Zhang, J. Nangreave, Y. Liu, H. Yan. Structural DNA Nanotechnology: State of the Art and Future Perspective. J. Am. Chem. Soc (2014).
  • J. Flory, C. Simmons, S. Lin, T. Jonhson, A. Andreoni, J. Zook, G. Chirlanda, Y. Liu, H. Yan, and P. Fromme,. Low Temperature Assembly of Functional 3D DNA-PNA-Protein Complexes. J. Am. Chem. Soc (2014).
  • J. Fu, Y. R. Yang, A. Johnson-Buck, Y. Liu, N. G. Walter, N. W. Woodbury, and H. Yan. Multi-enzyme Complexes on DNA Scaffolds Capable of Substrate Channeling with an Artificial Swinging Arm. Nature Nanotechnology (2014).
  • K. Pan, D. N. Kim, F. Zhang, M. Adendorff, H. Yan, M. Bathe. Lattice-free prediction of three-dimensional structure of programmed DNA assemblies. Nature Communications (2014).
  • L. Liang, J. Li, Q. Li, Q. Huang, J. Shi, H. Yan, and C. Fan. Single-particle Tracking and Modulation of Cell Entry Pathways of a Tetrahedral DNA Nanostructure in Live Cells. Angew Chem Int Ed (2014).
  • P. Dutta, S. Levenberg, A. Loskutov, D. Jun, R. Saer, J. Beatty, S. Lin, Y. Liu, N. Woodbury*, H. Yan. A DNA-Directed Light-Harvesting/Reaction Center System. J. Am. Chem. Soc (2014).
  • P. Dutta, S. Lin, A. Loskutov, S. Levenberg, D. Jun, R. Saer, J. Beatty, Y. Liu, H. Yan, and N. Woodbury. Regengineering the Optical Absorption Cross-section of Photosynthetic Reaction Centers. J. Am. Chem. Soc (2014).
  • S. Jiang, H. Yan, and Y. Liu. Kinetics of DNA Tile Dimerization. ACS Nano (2014).
  • W. Li, Y. Yang, S. Jiang, H. Yan, and Y. Liu. Controlled Nucleation and Growth of DNA Tile Arrays within Prescribed DNA Origami Frames and Their Dynamics. J. Am. Chem. Soc (2014).
  • A. Johnson-Buck, J. Nangreave, D. Kim, M. Bathe, H. Yan, N. Walter. Super-Resolution Fingerprinting Detects Chemical Reactions and Idiosyncrasies of Single DNA Pegboards. Nano Letters (2013).
  • A. Johnson-Buck, J. Nangreave, S. Jiang, H. Yan, N. Walter. Multifactorial Modulation of Binding and Dissociation Kinetics on Two-Dimensional DNA Nanostructures. Nano Letters (2013).
  • D. Han, S. Jiang, A. Samanta, Y. Liu, H.Yan. Unidirectional Scaffold-Strand Arrangement in DNA Origami. Angew Chem Int Ed (2013).
  • D. Han, S. Pal, Y. Yang, S. Jiang, J. Nangreave, Y. Liu, H. Yan. DNA Gridiron Nanostructures Based on Four-Arm Junctions. Science (2013).
  • F. Zhang, Y. Liu, H. Yan. Complex Archimedean Tiling Self-assembled from DNA Nanostructures. J. Am. Chem. Soc (2013).
  • J. Flory, S. Shinde, S. Lin, Y. Liu, H. Yan, G. Ghirlanda, P. Fromme. PNA-peptide Assembly in a 3D DNA Nanocage at Room Temperature. J. Am. Chem. Soc (2013).
  • M. Liu, J. Fu, C. Hejesen, Y. Yang, N. W. Woodbury, K. Gothelf, Y. Liu, H. Yan. A DNA Tweezer-Actuated Enzyme Nanoreactor. Nature Communications (2013).
  • O. Schulz, Z. Zhao, A. Ward, M. Koenig, F. Koberling, Y. Liu, J. Enderlein, H. Yan and R. Ros. Tip Induced Fluorescence Quenching for Nanometer Optical and Topographical Resolution. Optical Nanoscopy (2013).
  • Q. Mei, R. H. Johnson, X. Wei, F. Su, Y. Liu, L. Kelbauskas, S. Lindsay, D. R. Meldrum, and H. Yan. On-chip isotachophoresis separation of functional DNA origami capture nanoarrays from cell lysate. Nano Research (2013).
  • S. Pal, P. Dutta, H. Wang, Z. Deng, S. Zou, H. Yan, Y. Liu. Quantum Efficiency Modification of Organic Fluorophores Using Gold Nanoparticles on DNA Origami Scaffolds. J. Phys. Chem. C (2013).
  • W. Li, Y. Yang, H. Yan, Y. Liu. 3-Input Majority Logic Gate and Multiple Input Logic Circuit Based on DNA Strand Displacement. Nano Letters (2013).
  • X. Liu, Y. Liu, H. Yan. Functionalized DNA Nanostructures for Nanomedicine. Israel Journal of Chemistry (2013).
  • X. Wei, J. Nangreave, S. Jiang, H. Yan, Y. Liu. Mapping the Thermal Behavior of DNA Origami Nanostructures. J. Am. Chem. Soc (2013).
  • Y. Yang, Z. Zhao, F. Zhang, J. Nangreave, Y. Liu, H. Yan. Self-assembly of DNA Rings from Scaffold Free DNA Tiles. Nano Letters (2013).
  • Z. Deng, S. Pal, A. Samanta, H. Yan, Y. Liu. DNA Functionalization of Colloidal II-VI Semiconductor Nanowires. Chemical Sciences (2013).
  • Z. Zhao, Y. Liu, H. Yan. DNA Origami Templated Self-assembly of Discrete Length Single Wall Carbon Nanotubes. Org. Biomol. Chem (2013).
  • A. V. Pinheiro, J. Nangreave, S, Jiang, H. Yan, Y. Liu. Steric Crowding and the Kinetics of DNA Hybridization within a DNA Nanostructure System. ACS Nano (2012).
  • F. Zhang, J. Nangreave, Y. Liu, H. Yan. Reconfigurable DNA Origami to Generate Quasi-Fractal Patterns. Nano Letters (2012).
  • J. Fu, H. Yan. Controlled Drug Release by a Nanorobot. Nature Biotechnology (2012).
  • J. Fu, M. Liu, Y. Liu, H. Yan. Spatially-Interactive Biomolecular Networks Organized by Nucleic Acid Nanostructures. Acc. Chem. Res (2012).
  • J. Fu, M. Liu, Y. Liu, N. W. Woodbury, H. Yan. Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures. J. Am. Chem. Soc (2012).
  • N. Lu, H. Pei, Z. Ge, C. R. Simmons, H. Yan, C. Fan. Charge Transport within A Three-Dimensional DNA nanostructure Framework. J. Am. Chem. Soc (2012).
  • Q. Jiang, C. Song, J. Nangreave, X. Liu, L. Lin, D. Qiu, Z. Wang, G. Zou, X. Liang, H. Yan, B. Ding. DNA Origami as a Carrier for Circumvention of Drug Resistance. J. Am. Chem. Soc (2012).
  • X. Liu, Y. Xu, T. Yu, C. Craig, Y. Liu, H. Yan, Y. Chang. A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines,. Nano Letters (2012).
  • Y. Yang, D. Han, J. Nangreave, , Y. Liu, H. Yan,. DNA Origami with Double-Stranded DNA As a Unified Scaffold. ACS Nano (2012).
  • Z. Deng, A. Sanmanta, J. Nangreave, H. Yan, Y. Liu. Robust DNA Functionalized Core/Shell Quantum Dots with Fluorescent Emission Spanning from UV-Vis to Near IR and Compatible with DNA Directed Self-Assembly. J. Am. Chem. Soc (2012).
  • Z. Li, L. Wang, H. Yan, Y. Liu. Effect of DNA Hairpin Loops on the Twist of Planar DNA Origami Tiles. Langmuir (2012).
  • J. Fu, H. Yan. Controlled Drug Release by a Nanorobot. (2012).
  • A. Pinheiro, D. Han, W. M. Shih,*, H. Yan*. Challenges and Opportunities for Structural DNA Nanotechnology. Nature Nanotechnology (2011).
  • C. R. Simmons , D.Schmitt , X. Wei , D. Han , A. M. Volosin , D. M Ladd , D. Seo , Y. Liu , and H Yan. Size-Selective Incorporation of DNA Nanocages into Nanoporous Antimony-doped Tin Oxide Materials. ACS Nano (2011).
  • D. Han*, S. Pal, J. Nangreave, Z. Deng, Y. Liu*, H. Yan*. DNA Origami with Complex Curvatures in Three-dimensional Space. Science (2011).
  • J. Nangreave, H. Yan, Y. Liu*. DNA Nanostructures as Models for Evaluating the Role of Enthalpy and Entropy in Polyvalent Binding. J. Am. Chem. Soc (2011).
  • P. Dutta, R. Varghese, S. Lin, H. Yan, Y. Liu*. DNA Directed Artificial Light Harvesting Systems. J. Am. Chem. Soc (2011).
  • Q. Mei, X. Wei, F. Su, Y. Liu, C. Youngbull, R. Johnson, S. Lindsay, H. Yan*, D. Meldrum*. Stability of DNA Origami Nanoarrays in Cell Lysate. Nano Letters (2011).
  • S. Pal, Z. Deng, Y. Liu*, H. Yan*. DNA Origami Directed Self-assembly of Anisotropic Plasmonic Nanostructures. J. Am. Chem. Soc (2011).
  • S.Pal, R. Varghese, H. Yan*, Y. Liu*. Site Specific Synthesis and in-situ Immobilization of Fluorescent Silver Nanoclusters on DNA Nanoscaffolds Using Tollens Reaction. Angew Chem Int Ed (2011).
  • T. Torring, N. V. Voigt, J. Nangreave, H. Yan*, K. Gothelf*. DNA Origami: A quantum leap for self-assembly of complex structures. Chem. Soc. Rev (2011).
  • X. Liu, H. Yan, Y. Liu*, Y. Chang*. Targeted Cell-Cell Interactions by DNA Nanoscaffold-Templated Multivalent Bi-specific Aptamers. Small (2011).
  • Z. Deng, L. Tong, S. Lin, M. Flores, J. Cheng, H. Yan, Y. Liu*. High Quality Manganese-Doped Zinc Sulfide Quantum Rods with Tunable Dual-Color and Multi-Photon Emissions. J. Am. Chem. Soc (2011).
  • Z. Zhao, Y. Liu*, H. Yan*. Encapsulation of Gold Nanoparticles in a DNA Origami Cage. Angew Chem Int Ed (2011).
  • Z. Zhao, Y. Liu, H. Yan*. Organizing DNA Origami Tiles Into Larger Structures Using Pre-formed Scaffold Frames. Nano Letters (2011).
  • B. Ding*, Z. Deng, H. Yan, S. Cabrini, R. Zukerman, J. Borker*. Gold Nanoparticles Self-similar Chain Structure Organized by DNA Origami. J. Am. Chem. Soc (2010).
  • B. Ding, H. Wu, W. Xu, Z. Zhao, Y. Liu, H. Yu*, H. Yan*. Interconnecting Gold islands with DNA Origami Nanotubes. Nano Letters (2010).
  • D. Han, S. Pal, Y. Liu*, H. Yan*. Folding and Cutting DNA into Reconfigurable Topological Nanostructures. Nature Nanotechnology (2010).
  • H. Pei, N. Lu, Y. Wen, S. Song, Y. Liu, H. Yan*, C. Fan*. A DNA Nanostructure-based Biomolecular Probe Carrier Platform for Electrochemical Biosensing. Advanced Materials (2010).
  • J. Nangreave, D. Han, Y. Liu, H. Yan*. DNA Origami: A History and Current Perspective. Curr Opin Chem Biol (2010).
  • K.Lund, A. J. Manzo, N. Dabby, N. Michelotti, A. Johnson-Buck, J. Nangreave, Steven Taylor, R. Pei, M. N. Stojanovic*, N. G. Walter*, E. Winfree*, H. Yan*. Molecular Robots Guided by Prescriptive Landscapes. Nature (2010).
  • N. Stephanopoulos; M. Liu; G. Tong; Z. Li; Y. Liu; H. Yan*; M. Francis*. Immobilization and One-Dimensional Arrangement of Virus Capsids With Nanoscale Precision Using DNA Origami. Nano Lett (2010).
  • R. Chhabra, J. Sharma, Y. Liu, S. Rinker, H. Yan*. DNA Self-assembly for Nanomedicine. Advanced Drug Delivery Reviews (2010).
  • S. Pal, Z. Deng, B. Ding, H. Yan*, Y. Liu*. DNA Origami Directed Self-assembly of Discrete Silver Nanoparticle Architectures. Angew Chem Int Ed (2010).
  • S. Williams, K. Lund, C. Lin, P. Wonka*, S. Lindsay*, H. Yan*. Tiamat: A Three Dimensional Editing Tool for Complex DNA Structures. DNA Computing: Lecture Notes in Computer Science (2010).
  • Z. Deng*, O. Schulz, S. Lin, B. Ding, X. Liu, X. Wei, R. Ros, H. Yan, Y. Liu*. Aqueous Synthesis of Zinc-Blende CdTe/CdS Magic-Core/Thick-Shell Tetrahedral Shaped Nanocrystals with Emission Tunable to Near-Infrared. J. Am. Chem. Soc (2010).
  • Z. Deng, H. Yan, Y. Liu*. Controlled Colloidal Growth of Ultra-Thin Single-Crystal ZnS Nanowires with Magic-Size Diameter. Angew. Chem. Int. Ed (2010).
  • Z. Li, M. Liu, L. Wang, J. Nangreave, H. Yan, Y. Liu*. Molecular Behavior of DNA Origami in Higher Order Self-assembly. J. Am. Chem. Soc (2010).
  • Z. Zhao, H. Yan*, Y. Liu*. A Route to Scale up DNA Origami using DNA Tiles as Folding Staples. Angew Chem Int Ed (2010).
  • Z. Zhao, H. Yan*, Y. Liu*,. A Route to Scale up DNA Origami using DNA Tiles as Folding Staples,. Angew Chem Int Ed (2010).
  • A. E. Gerdon, S.-S. Oh, W. Hsieh, Y. Ke, H. Yan*, H. T. Soh*,. Controlled Delivery of DNA Origami on Patterned Surface,. Small (2009).
  • C. Andersen, M. Knudsen, R. Chhabra, Y. Liu, H. Yan*, K. Gothelf*,. Distance Dependent Interhelical Couplings of Organic Rods Incorporated in DNA 4-Helix Bundles,. Bioconjugation Chemistry (2009).
  • C. Lin, Y. Ke, Z. Li, J. Wang, Y. Liu*, H. Yan*. Mirror Image DNA Nanostructures for Chiral Supramolecular Assemblies. Nano Letters (2009).
  • C. Lin, Y. Liu, H. Yan*. Designer DNA Nanoarchitectures. Biochemistry (2009).
  • J. Nangreave, H. Yan*, Y. Liu*,. Studies of Thermal Stability of Multivalent DNA Hybridization in a Nanostructured System,. Biophys. J (2009).
  • J. Sharma, R. Chhabra, A. Cheng, J. Brownell, Y. Liu*, H. Yan*. Control of Self-Assembly of DNA?Tubules Through Integration of Gold Nanoparticles. Science (2009).
  • L. A. Stearns, R. Chhabra, J. Sharma, Y. Liu, W. T. Petuskey, H. Yan*, J. C. Chaput*,. Template-Directed Nucleation and Growth of Inorganic Nanoparticles on DNA Scaffolds,. Angew. Chem. Int. Ed (2009).
  • R. Chhabra, J. Sharma, H. Wang, S. Lin, H. Yan, S. Zou, S. Lindsay, Y. Liu*,. Distance-dependent interactions between gold nanoparticles and fluorescent molecules with DNA as tunable spacers,. Nanotechnology, (2009).
  • S. Pal, J. Sharma, H. Yan, Y. Liu*,. Stable Silver Nanoparticle-DNA Conjugates for Directed Self-assembly of Core-Satelite Silver Nanoclusters,. Chemical Communication (2009).
  • Y. Ke, J. Sharma, M. Liu, K. Jahn, Y. Liu*, H. Yan*,. Scaffolded DNA Origami of a DNA Tetrahedron Molecular Container,. Nano. Lett (2009).
  • Y. Ke, S. Douglas, M. Liu, J. Sharma, A. Cheng, A. Leung, Y. Liu, W. Shih*, H. Yan*,. Multilayer DNA Origami Packed On a Square Lattice,. J. Am. Chem. Soc (2009).
  • Z. Deng*, H. Yan, Y. Liu*,. Band Gap Engineering of Quaternary Alloyed ZnCdSSe Quantum Dots via a Facile Phosphine-Free Colloidal Method,. J. Am. Chem. Soc (2009).
  • C. Lin, H. Yan*,. Engaging Enzyme Cascades on DNA Scaffolds. (2009).
  • C. Lin, Y. Liu, H. Yan*,. Designer DNA Nanoarchitectures. (2009).
  • Y. Liu, H. Yan*,. Coordinating Corners. (2009).
  • Y. Liu, H. Yan*,. Designer Curvature. (2009).
  • C. Lin, S. Rinker, X. Wang, Y. Liu, N. C. Seeman, H. Yan*. In-vivo Cloning of DNA Nanostructures. Proc. Natl. Acad. Sci (2008).
  • C. S. Anderson, H. Yan, K. V. Gothelf. Bridging One Helical Turn in dsDNA by Templated Dimerization ?of Molecular Rods. Angew Chem Int Ed (2008).
  • J. Sharma, R. Chhabra, C. S. Anderson, K. V. Gothelf, H. Yan, Y. Liu. Toward Reliable Gold Nanoparticle Patterning on Self-assembled DNA Nanoscaffold. J. Am. Chem. Soc (2008).
  • J. sharma, R. Chhabra, H. Yan, Y. Liu*. A Facile In situ Generation of Dithiocarbamate Ligands for Stable Gold Nanoparticle-Oligonucleotide Conjugates. Chemical Communication (2008).
  • J. Sharma, Y. Ke, C. Lin, R. Chhabra, Q. Wang, J. Nangreave, Y. Liu*, H. Yan*. DNA Tile Directed Self-assembly of Quantum Dots into Two-dimensional Nanopatterns. Angew Chem Int Ed (2008).
  • S. Rinker, Y. Ke, Y. Liu*, H. Yan*. Self-assembled DNA Nanostructures for distance dependent multivalent ligand-protein binding. Nature Nanotechnology (2008).
  • Y. Xu, Q. Wang, P. He, Q. Dong, F. Liu, Y. Liu, L. Lin, H. Yan, X. Zhao. Cell Nucleus Penetration by Quantum Dots Induced by Nuclear Staining Organic Fluorophore and UV-Irradiation. Advanced Materials (2008).
  • Z. Li, Y. Ke, C. Lin, H. Yan, Y. Liu. Subtractive Assembly of DNA Nanoarchitectures Driven by Fuel Strand Displacement. Chem. Comm (2008).
  • . . Advanced Drug Delivery (2008).
  • . . Encyclopedia of Complexity and System Science (2008).
  • B Williams, K Lund, Y Liu, Hao Yan, J Chaput. Self-assembled Peptide Nanoarrays: A new approach to studying protein-protein interactions. Angew Chem It Ed (2007).
  • C Lin, Y Liu, Hao Yan. Self-assembled Combinatorial Encoding Nanoarrays for Multiplexed Biosensing. Nano Letters (2007).
  • C. Lin, Yan Liu, Hao Yan. Self-assembled Combinatorial Encoding Nanoarrays for Multiplexed Biosensing. Nano Lett (2007).
  • J Sharma, R Chhabra, Hao Yan, Y Liu. pH-driven Conformational Switch of "i-motif" DNA for Reversible Assembly of Gold Nanoparticles. Chemical Communication (2007).
  • . . Biological Studies and Applications of Engineered Nanostructures (2007).
  • Chhabra, R. (author) ,Sharma, J. (author) ,Liu, Y. (author) ,Yan, Hao (corresponding author) . . Bio-Applications of Nanoparticles (2007).
  • C Lin, E Katilius, Yan Liu, Hao Yan. Self-assembled Signaling Aptamer Nanoarrays for Protein Detection. Angew. Chem. Int. Ed (2006).
  • C Lin, M Xie, J Chen, Y Liu, Hao Yan. Rolling Circle Amplification of a DNA Nano- junction. Angew. Chem. Int. Ed (2006).
  • C Lin, M Xie, J Chen, Y Liu, Hao Yan. Rolling Circle Amplification of a DNA Nano-junction. Angew. Chem. Int. Ed (2006).
  • C Lin, Yan Liu, S Rinker, Hao Yan. DNA tile Based Self-assembly: Building Complex Nano-architectures. ChemPhysChem (2006).
  • Hao Yan, B Xu. Towards Rapid DNA Sequencing: Detecting Single-Stranded DNA with a Solid-State Nanopore. Small (2006).
  • J Sharma, R Chhabra, Yan Liu, Y Ke, Hao Yan. DNA templated self-assembly of two-dimensional and periodical gold nanoparticle arrays. Angew. Chem. Int. Ed (2006).
  • K Lund, B Williams, Y Ke, Yan Liu, Hao Yan. DNA nanotechnology: a rapidly evolving field. Current Nanoscience (2006).
  • L Lin, H Wang, Yan Liu, Hao Yan, S Lindsay. Recognition imaging with a DNA aptamer. Biophysical J (2006).
  • R Chhabra, J Sharma, Yan Liu, Hao Yan. Addressable Molecular Tweezers for DNA templated coupling reactions. Nano Lett (2006).
  • S Rinker, Y Liu, Hao Yan. Two Dimensional LNA/DNA arrays: estimating the helicity of LNA/DNA hybrid duplex. Chemical Communication (2006).
  • Y J Zhang, Yan Liu, Hao Yan. Periodic Square-like gold nanoparticle arrays templated by a DNA nanogrids on a surface. Nano Lett (2006).
  • Y Ke, Yan Liu, J Zhang, Hao Yan. A Study of DNA tube formation mechanisms using 4-, 8- and 12-helix DNA nanostructures. J. Am. Chem. Soc (2006).
  • Yan, Hao,Yan, Liu. DNA nanotechnology: an evolving field. Nanotechnology: Science and Computation (2006).
  • K Lund, Yan Liu, S Lindsay, Hao Yan. Self-assembling Molecular Pegboard. J. Am. Chem. Soc (2005).
  • Yan Liu, C Lin, H Li, Hao Yan. Aptamer directed Self-assembly of Proteins on a DNA Nanostructure. Angew. Chem. Int. Ed (2005).
  • Yan Liu, Hao Yan. Modular Self-assembly of DNA Lattice with Tunable Periodicity. Small (2005).
  • Yan Liu, Y Ke, Hao Yan. Self-assembly of symmetric finite size DNA nanoarrays. J. Am. Chem. Soc (2005).
  • . . Bioelectronics (2005).
  • . . Nanotechnology: Science and Computation (2005).
  • Reif, J, LaBean, T, Sahu, S, Yan, Hao, Yin, P. Design, Simulation, and Experimental Demonstration of Self-assembled DNA Nanostructures and Motors. Springer-Verlag (2005).
  • Seeman, N, Ding, B, Liao, S, Wang, T, Sherman, W, Constantinou, P, Kopatsch, J, Mao, C, Sha, R, Liu, F, Yan, Hao, Lukeman, P. Experiments in Structural DNA Nanotechnology: Arrays and Devices. (2005).
  • Sha, R, Zhang, X, Liao, S, Constantinou, P, Ding, B, Wang, T, Garibotti, A, Zhong, H, Israel, L, Wang, X, Wu, G, Chakraborty, B, Chen, J, Zhang, Y, Mao, C, Yan, Hao, Kopatsch, J, Zheng, J, Lukeman, P, Sherman, W, Seeman, N. Motifs and Methods in Structural DNA Nanotechnology. Mepco Schlenk Engineering College (2005).
  • Sha, R, Zhang, X, Liao, S, Constantinou, P, Ding, B, Wang, T, Garibotti, A, Zhong, H, Israel, L, Wang, X, Wu, G, Chakraborty, B, Chen, J, Zhang, Y, Yan, Hao, Shen, Z, SHen, W, Sa-Ardyen, P, Kopatsch, J, Zheng, J, Lukeman, P, Sherman, W, Mao, C, Jonoska, N, Seeman, N. Structural DNA Nanotechnology: Molecular Construction and Composition. Springer-Verlag (2005).
  • Hanying Li, Sung Ha Park, John Reif, Thomas LaBean, Hao Yan. DNA templated self-assembly of protein and nanoparticle linear arrays. J. Am. Chem. Soc (2004).
  • Hao Yan. Nucleic Acid Nanotechnology. Science (2004).
  • S Park, Hao Yan, J Reif, T LaBean, G Finkelstein. Electronic nanostructures templated on self-assembled DNA scaffolds. Nanotechnology (2004).
  • Yin Peng, Hao Yan, XiaoJu Guan, Andrew Turberfield, John Reif. An autonomous Unidirectional DNA walker. Angew. Chem. Int. Ed (2004).
  • Zhiyong Shen, Hao Yan, Tong Wang, Nadrian Seeman. Paranemic Crossover DNA: A Generalized Holliday Structure with Applications in Nanotechnology. J. Am. Chem. Soc (2004).
  • Yan, Hao, Yin, P, Park, S, Li, H, Feng, L, Guan, X, Liu, D, Reif, J, LaBean, T. Self-assembled DNA structures for nanoconstruction. (2004).
  • Hao Yan, L Feng, T LaBean, J Reif. Parallel Molecular Computation of Pair-wise Exclusive-Or (XOR) using DNA "String Tile" Self-Assembly. J. Am. Chem. Soc (2003).
  • Hao Yan, N Seeman. Edge-sharing DNA triangles and One-dimensional self-assembly. J. Supramol. Chem (2003).
  • Hao Yan, S Park, G Finkelstein, J Reif, T LaBean. DNA templated Self-assembly of Protein Arrays and Highly Conductive Nanowires. Science (2003).
  • Yan, Hao, LaBean, T, Feng, L, Reif, J. Directed Nucleation Assembly of DNA tile Complexes for Barcode Patterned Lattices. (2003).
  • Hao Yan, X Yang, Z Shen, N Seeman. A Robust Sequence-dependent Rotary DNA Device. Nature (2002).
  • X Zhang, Hao Yan, Z Shen, N Seeman. Paranemic Cohesion of Topologically-Closed DNA Molecules. J. Am. Chem. Soc (2002).
  • T LaBean, Hao Yan, J Kopatsch, F Liu, E Winfree, J Reif, N Seeman. The Construction, analysis, ligation and self-assembly of DNA Triple Crossover Molecules. J. Am. Chem. Soc (2000).
  • . . Frontiers of Nano-Optoelectronic Systems (2000).
  • D Jiang, Z Ge, H Im, C England, D Ni, J Hu, L Zhang, C Kutyreff, H Yan, Y Liu.  DNA-Origami Nanostructures.  Nature Biomed. Eng. (2018).
  • X Qi, F Zhang,* Z Su', S Jiang, D Han, B Ding, Y Liu, W Chiu, P Yin, H Yan.*  Programming Molecular Topologies from Single-Stranded Nucleic Acids.  Nature Communications (2018).
  • F Hong, S Jiang, X Lan, R Narayanan, P Sulc, F Zhang,*, Y Liu,*, H Yan.*  Layered-Crossover Tiles with Precisely Tunable Angles for 2D and 3D DNA Crystal Engineering.  J. Am. Chem. Soc.(2018).
  • X Lan, T Liu, Z Wang, A Govorov, H Yan, Y Liu.  DNA-Guided Plasmonic Helix with Switchable Chirality.  J. Am. Chem. Soc. (2018).
  • F Zhang, C Simmons, J Gates, Y Liu, H Yan.  Self-Assembly of a 3D DNA Crystal Structure with Rationally Designed Six-Fold Symmetry.  Angew Chem. Int. Ed. (2018).
  • X Liu, F Zhang, X Ling, M Pan, P Liu, W Li, B Zhu, J Li, H Chen, L Wang, J Lin, Y Liu, D Zhao, H Yan, C Fan.  Complex Silica Composite Nanomaterials Templated with DNA Origami.  Nature (2018).
  • Z Ge, Z Su, C R Simmons, J Li, S Jiang, W Li, Y Yang, Y Liu, W Chiu, C Fan, H Yan.  ACS Appl. Mater. Interfaces (2018).
  • J Li, A Johnson-Buck, Y Yang, W Shih, H Yan, N Walter.  Exploring the speed limit of toehold exchange with a cartwheeling DNA acrobat.  Nature Nanotechnology (2018).
  • S Li, Q Jiang, S Liu, Y Zhang, Y Tian, C Song, J Wang, Y Zou, G Anderson, J Han, Y Chang, Y Liu, C Zhang, L Chen, G Zhou, G Nie, H Yan, B Ding, Y Zhao.  A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo.  Nature Biotechnology (2018).
  • E Boulais, N Sawaya, R Veneziano, A Andreoni, S Lin, N Woodbury, H Yan,* M Bathe.*  Programmed coherent coupling in a DNA-based excitonic circuit.  Nature Materials (2018).
Research Activity: 
Summer 2020
Course NumberCourse Title
BDE 792Research
Spring 2020
Course NumberCourse Title
BCH 361Principles of Biochemistry
BDE 792Research
BDE 799Dissertation
Spring 2019
Course NumberCourse Title
BCH 361Principles of Biochemistry
BDE 792Research
BDE 799Dissertation
Spring 2018
Course NumberCourse Title
CHM 460Biological Chemistry
Fall 2017
Course NumberCourse Title
BIO 495Undergraduate Research
Spring 2017
Course NumberCourse Title
BCH 361Principles of Biochemistry
Fall 2016
Course NumberCourse Title
BCH 461General Biochemistry
Spring 2016
Course NumberCourse Title
BCH 361Principles of Biochemistry
Presentations: 
  • Hao Yan. Designer DNA Nanoarchitectures for Multivalency. 3rd International Symposium on Multivalency in Chemistry and Biochemistry (Oct 2014).
  • Hao Yan. Designer DNA Nanoarchitectures for Programmable Self-assembly. ACS Central Regional Meeting, Session on DNA/RNA Nanostructures (Oct 2014).
  • Hao Yan. DNA Origami and the Different Functionalization Techniques. Gordon Research Conference: Plasmonics: Manipulating Light-Matter Interaction at the Nanoscale (Jul 2014).
  • Hao Yan. Designer DNA Nanoarchitectures for Programmable Self-assembly. The Third International DNA Nanotechnology Conference, (May 2014).
  • Hao Yan. Designer DNA Nanoarchitectures for Programmable Self-assembly. International Workshop on DNA-Based Nanotechnology: Digital Chemistry (May 2014).
  • Hao Yan. Designer DNA Nanoarchitectures for Programmable Self-assembly. 40th Annual Naff Symposium on Chemistry and Molecular Biology (Apr 2014).
  • Hao Yan. Designer DNA Nanoarchitectures for Programmable Self-assembly. Department of Chemistry colloquim, U. of Michigan (Apr 2014).
  • Hao Yan. Designer DNA Nanoarchitectures for Programmable Self-assembly. Department of Chemistry colloquim, U. of Chicago (Mar 2014).
  • Hao Yan. New Innovations in Biotechnology: Molecular Design and Biomimicry. Presidential Engagement Program, Building Solutions to Grand Challenges: Creating Societal Impact Th (Mar 2014).
  • Fei Zhang, Yan Liu, Hao Yan. Complex Archimedean Tilings Self-assembled From DNA Nanostructures. 19th International Meeting on DNA Computing and Molecular Programming (Sep 2013).
  • Wei Li, Yan Liu, Hao Yan. 3-Input Majority Logic Gate and Multiple Input Logic Circuit Based on DNA Strand Displacement. 19th International Meeting on DNA Computing and Molecular Programming (Sep 2013).
  • Hao Yan. Conference Organizing Committee Chair. 19th International Meeting on DNA Computing and Molecular Programming (Sep 2013).
  • Hao Yan. Designer DNA Architectures for Programmable Self-assembly. Bio-Inspired Computing: Theories and Applications 2013 (BIC-TA 2013), Huangshan, China, July 12-14, (Jul 2013).
  • Hao Yan. Designer DNA Architectures for Programmable Self-assembly. Wyss Institute of Bioinspired Engineering, Harvard University, May 13, 2013 (May 2013).
  • Hao Yan. Designer DNA Architectures for Programmable Self-assembly. Department of Bioengineering, MIT, May 9, 2013 (May 2013).
  • Hao Yan. Designer DNA Architectures for Programmable Self-assembly. Department of Chemistry, Penn State Univ, April 3, 2013 (Apr 2013).
  • Hao Yan. Designer DNA Architectures for Programmable Self-assembly. 10th Annual Conference, Foundation of Nanoscience, Self-assembled Achitectures and Devices, Snowbird (Apr 2013).
  • Hao Yan. "Designer DNA Nanostructures",. the 14th IUPAC conference on Polymers and Organic Chemistry, Doha, Qatar, Jan. 6-9, 2012 (Nov 2012).
  • Hao Yan. "Designer DNA Architectures". DNATEC workshop, Arhus, Denmark, August 13. 2012 (Aug 2012).
  • Hao Yan. "Designer DNA Nanostructures for Nanobiotechnology". Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, (May 2012).
  • Hao Yan. "Designer DNA Nanostructures". Seminar Series in Chemical Biology, Yale University – New Heaven CT, April 4. 2012 (Apr 2012).
  • Hao Yan. "Designer DNA Nanostructures". Department of Chemistry, University of Nebraska - Lincoln, NE, April 6. 2012 (Apr 2012).
  • Hao Yan. "Designer DNA Architectures". DNA Nanotechnology Conference: From Structure to Function, Shanghai, China, March 16-19, 2012 (Mar 2012).
  • Hao Yan. "Designer DNA Architectures for Nanotechnology". the 243rd ACS National Meeting, San Diego, CA, March 25, 2012 (Mar 2012).
  • Hao Yan. Designer DNA Nanostructures. the 17th International Conference on DNA Computing and Molecular Programming (Sep 2011).
  • Hao Yan. Designer DNA Nanostructures. About time Symposium In Honor of Ned Seeman (Apr 2011).
  • Hao Yan. Designer DNA Nanostructures. Departmental seminar (Feb 2011).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. The 8th iCeMS International Symposium on Meso-Control of Functional Architecture, Kyoto, Japan (Nov 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Graduate summer school in molecular self-assembly hosted by the Interdisciplinary Nanoscience Cente (Aug 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, China (Jun 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Fifth Sino-US Nano Forum, Suzhou Institute of Nanotechnology and Nanobioncs (SINANO), Chi (Jun 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. School of Chemistry and Molecular Engineering, East China University of Science & Technology, Shangh (Jun 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Gordon Research Conference on Nobel Metal Nanoparticles, Mount Holyoke College, MA (Jun 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. School of Chemistry, Shandong University, Jinan, China (May 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Department of Biomedical Engineering, (May 2010).
  • Hao Yan. Designer DNA Nanostructures for Directed Self-assembly. Center for Nanofabrication, U. of Washington, Seattle, WA, (May 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Workshop on Bio-directed Assembly, Keystone, CO, (May 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. School of Chemistry, Shandong University, Jinan, China (May 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Symposium OO: Hierarchical Self Assembly of Functional Materials from Nanoscopic- to Mesoscopic-Leng (Apr 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Foundations of Nanoscience: Self-assembled Architectures and Devices, Snowbird, Utah, April 27-29, 2 (Apr 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Workshop on Soft Nanomaterial Synthesis, Molecular Foundry, Lawrence Berkeley National Lab (Mar 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Session on "DNA Nanomachines in Vitro and Inside Living Cells", 54th Annual Biophysical Soc (Feb 2010).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Symposium on "Probing the BioNano Self-assembly World", Pittcon 2010 (Feb 2010).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. JBiophysics Seminar, Dept. of Physics and Astronomy, Rice University, Houston, TX, (Nov 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. JnanoUtah2009: 5th Annual Utah Statewide Nanotechnology Conference, Salt Lake City, Utah, (Oct 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. Dept. of Chemical and Nuclear Engineering, U. of New Mexico, Albquerque, NM, (Sep 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. Institute of Applied Physics, CAS, Shanghai, (Jul 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. Dept. of Chemistry, Univ. of Science and Technology of China, Hefei, (Jul 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. DNA Nanotechnology workshop, National Center for Nanoscience and Technology, Beijing, (Jul 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. Materials Science and Engineering Department, Iowa State University, Ames, IA, (Apr 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. Mini-symposium of Center for DNA Nanotechnology, Duke University, Durham, NC, (Mar 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. Department of Chemistry, Florida State University, Tallahassee, FL, (Feb 2009).
  • H. Yan. "Designer DNA Nanostructures for Nanobiotechnology",. Joint MIT and Harvard Inorganic Chemistry Seminar Series, Department of Chemistry, MIT, Cambridge, M (Jan 2009).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Departments of Material Science and Mechanical Engineering , UC Santa Babara, Santa Babara, CA Oct (Oct 2008).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. the Joint Symposium of 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids ( (Sep 2008).
  • Yan, Hao. Designer DNA Nanostructures for Nanobiotechnology. SPIE Optics and Photonics Meeting (Biosensing Symposium) (Aug 2008).
  • Yan, Hao. Structural DNA Nanotechnology: Information Guided Self-assembly. Gordon Research Conference, Session on Bioorganic Chemistry (Jun 2008).
  • Yan, Hao. Designer DNA Nanostructures for Nanobiotechnology. International Symposium for DNA based nanodevices (May 2008).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. International Symposium for DNA based nanodevices, Jena, German, May 29-30, 2008 (May 2008).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Department of Chemistry, Texas A &M University, College Station, TX, April 4, 2008 (Apr 2008).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. 3rd Annual Arizona Nanotechnology Cluster Symposium, Scottsdale, AZ, April 10, 2008 (Apr 2008).
  • Hao Yan. DNA based Nanscale Scaffolds, Assembly and Molecular Robotics. Office of Naval Research Workshop on DNA based Nanofabrication, Washington DC, April 11, 2008 (Apr 2008).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. Foundations of Nanoscience: Self-assembled Architectures and Devices (FNANO08), Snowbird, Utah, Apri (Apr 2008).
  • Hao Yan. Structural DNA Nanotechnology: Information Guided Self-assembly. Departmental Seminar, Department of Chemistry and Chemical Engineering, Caltech (Mar 2008).
  • Hao Yan. Designer DNA Nanostructures for Nanobiotechnology. 2008 William H. Nichols Symposium, New York Section of the American Chemical Society, White Plains, (Mar 2008).
  • Hao Yan. Structural DNA Nanotechnology: Information Guided Self-assembly. Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah, March. 27, 2008 (Mar 2008).
  • Yan, Hao. DNA based self-assembly of nanostructures. Fall 2007 Materials Research Society National Meeting (Nov 2007).
  • Yan, Hao. Structural DNA Nanotechnology: Information Guided Self-assembly. Departmental Seminar (Oct 2007).
  • Yan, Hao. DNA based self-assembly of nanostructures. Mini-symposium on DNA based Nanotechnology (Aug 2007).
  • Yan, Hao. DNA based self-assembly of nanostructures. 234th ACS National Meeting (Aug 2007).
  • Yan, Hao. DNA based self-assembly of nanostructures. Albany 2007: The 15th conversation on biomolecular structures and dynamics (Jun 2007).
  • Yan, Hao. DNA based self-assembly of nanostructures. The Second Advanced Materials Workshop (Jun 2007).
  • Yan, Hao. DNA based self-assembly of nanostructures. Academia Sinica (May 2007).
  • Yan, Hao. DNA based self-assembly of nanostructures. NSF Center for Hierarchical Manufacturing, U. of Massachusetts (May 2007).
  • Yan, Hao. DNA based self-assembly of nanostructures. State Key Laboratory of Molecular Cancer Institute (Jan 2007).
  • Yan, Hao. Nanoparticle based multi-component and multi-functional nanostructures. State Key Laboratory of Molecular Cancer Institute (Jan 2007).
  • Yan, Hao. DNA based self-assembly of hierarchical nanostructures. Arizona Nanocluster Symposium, Organized by Quanttera Co (Nov 2006).
  • Yan, Hao. DNA based self-assembly of nanostructures. Bionanotechnology Symposium organized by canadian institute for advanced research (Oct 2006).
  • Yan, Hao. DNA based self-assembly of nanostructures. Nanoscience and Nanotechnology Session 2006 SACNAS (Oct 2006).
  • Liu, Y, Yan, Hao. DNA-based self-assembly of nanostructures. The 9th Sanken International Symposium on Nanoscience and Nanotechnology 2006 (Sep 2006).
  • Yan, Hao. Development of Self-assembled and Combinatorial Signaling Aptamer Nanoarray. 12th International Meeting on DNA Based Computers (Jun 2006).
  • Yan, Hao. DNA based self-assembly of nanostructures. (Jun 2006).
  • Yan, Hao. DNA based self-assembly of nanostructures. International Symposium on DNA-Based Nanoscale Integration (May 2006).
  • Yan, Hao. DNA based self-assembly of nanostructures. Symposium on Frontier of Nanoscience (May 2006).
  • Yan, Hao. Experimental Progress in DNA based Self-assembly. 2nd Annual Conference of Fundation of Nanoscience (FNANO) (Apr 2006).
  • Yan, Hao. DNA based self-assembly of nanostructures. NSF workshop: The Synthesis of Complex Chemical Systems (Mar 2006).
  • Yan, Hao. DNA based self-assembly of nanostructures. meeting (Mar 2006).
  • Yan, Hao. DNA based self-assembly of nanostructures. VIII Annual Linz Winter Workshop on Single Molecule Research (Feb 2006).
  • Yan, Hao. DNA based self-assembly for hierarchical nanostructures. NSF Workshop: Emerging Opportunities of Nanoscience to Energy Conversion and Storage (Nov 2005).
  • Yan, Hao. DNA Nanobiotechnology. Department of Biomedical Engineerig (Oct 2005).
  • Yan, Hao. DNA based Nanobiotechnology. (Aug 2005).
  • Yan, Hao. DNA based nanobiotechnology. 2005 Scanning Probe Microscopy, Sensors and Nanostructures Meeting (Jun 2005).
  • Yan, Hao. DNA based Nanobiotechnology. Session on Developing Nano-Bio Interfaces, 2005 MRS Spring Meeting (Mar 2005).
  • Yan, Hao. DNA based nanotechnology: pattern and motion. Engineering a DNA world, Workshop sponsored by California Institute of Technology (Jan 2005).
  • Yan, Hao. DNA based Nanobiotechnology. Structure of Nanocrystals Workshop Sponsored by Michigan State University (Dec 2004).
  • Yan, Hao. DNA based self-assembly of hierarchical nanostructures. Mini-Symposium on DNA Self Assembly and Robotics (Oct 2004).
  • Yan, Hao. DNA based Nanotechnology: Pattern and Motion. ACS Rocky mountain analytical section (Aug 2004).
  • Yan, Hao. New Structures for DNA based Nanotechnology. DNA-Based Molecular Electronics, International Symposium (May 2004).
  • Yan, Hao. DNA Nanoactuator in Self-assembly. Foundations of Nanoscience: Self-assembled Architectures and Devices (Apr 2004).
  • Yan, Hao. DNA Self-assembly, Nanoactuators and Autonomous Unidirectional DNA Motor. 320th WE-Heraeus-Seminar "Nano-Physics of DNA", Physikzentrum (Mar 2004).
  • Yan, Hao. DNA Nanoactuators in Self-assembly. DARPA IPTO Workshop for Molecular Architectures from Self-Assembled Nanostructures (Feb 2004).
  • LaBean, T, Yan, Hao, Park, S, Feng, L, Yin, P, Li, H, Ahn, S, Liu, D, Guan, X, Reif, J. Overview of New Structures for DNA-based Nanofabrication and Computation. 6th International Conference on Computational Intelligence and Natural Computing (Sep 2003).
  • Yan, Hao. Self-assembly of DNA for Computing and Molecular Robotics. (Sep 2003).
  • Yan, Hao. Self-assembly of DNA for Nanofabrication and Molecular Robotics. (Aug 2003).
  • Yan, Hao. Self-assembly of DNA for Nanofabrication, Computing and Molecular Robotics. (Aug 2003).
  • Yan, Hao. Self-assembly of DNA for Nanofabrication, Computing and Molecular Robotics. Graduate School of Engineering (Aug 2003).
  • Yan, Hao. Tutorial: Self-assembly of Nanostructures. 9th International Meeting on DNA Based Computers (Jun 2003).
  • Yan, Hao, LaBean, T, Feng, L, Reif, J. Directed Nucleation Assembly of Barcode Patterned DNA Lattices. 9th International Meeting for DNA Based Computing (Jun 2003).
  • Yan, Hao, Park, S, Feng, L, Finkelstein, G, Reif, J, LaBean, T. 4x4 DNA Tile and Lattices: Characterization, Self-Assembly and Metallization of a Novel DNA Nanostructure Motif. 9th International Meeting for DNA Based Computing (Jun 2003).
  • Yan, Hao, Park, S, Feng, L, Finkelstein, G, Reif, J, LaBean, T. 4x4 DNA Tile and Lattices: Characterization, Self-Assembly and Metallization of a Novel DNA Nanostructure Motif. Biomolecular Stereodynamics (Jun 2003).
  • Yan, Hao. Parallel Molecular Computation of Pair-wise XOR Using DNA String Tile. 9th International Meeting on DNA Based Computers (Jun 2003).
  • Yan, Hao. Molecular Robotics for DNA Nanostructures. DARPA IPTO/NSF Bio-Computation/QIS Joint PI Meeting (May 2003).
  • Yan, Hao. DNA self-assembly for nanoconstruction and molecular robotics. Dept. of Chemistry and Chemical Biology (Jan 2003).
  • Yan, Hao, Zhang, X, Seeman, N. A Robust Sequence-Dependent Rotary DNA Nanomechanical Device. Biomolecular Stereodynamics (Jun 2001).
Service: 
  • President Crow’s Academic Council, Member (2014 - Present)
  • Faculty Search Committee for Molecular Design and Biomimicry, Chair (2014 - Present)
  • Nano Research, Member of Editorial Board, (2014 - Present)
  • DNATEC14: Digital Chemistry, Dresden, Germany, Co-Organizer (2014 - Present)
  • National Science Foundation, Reviewer (2014 - Present)
  • Science, Nature Chemistry, Nature Communications, JACS, Angew Chem etc., Reviewer (2014 - Present)
  • The Third International DNA Nanotechnology Conference, Suzhou, China, Co-Organizer (2014 - Present)
  • Faculty Search Committee for the Biomimicry position, Chair (2013 - Present)
  • Center for Molecular Design and Biomimicry, Biodesign Institute, Director (2013 - Present)
  • Departmental Strategic Planning Committee, Member (2013 - Present)
  • Accounts of Chemical Research, DNA Nanotechnology Special Issue Co-editor (2013 - Present)
  • International Society for Nanoscale Science, Computation and Engineering, President (2013 - Present)
  • 19th International Meeting in DNA Cumputing and Molecular Programming, Chair of Organizing Committee (2012 - Present)
  • Biophysics Joint Biodesign-Physics Faculty Search Committee, Member (2012 - Present)
  • Departmental Strategic planning Committee, member (2012 - Present)
  • International Meeting on DNA Computing and Molecular Programming, Member of Steering Committee (2012 - Present)
  • Symposium H "Mining Smartness from Nature" of CIMTEC 2012, International Advisory Board Member (2012 - Present)
  • International Conference on Bio-Inspired Computing: Theory and Applications (BIC-TA), Member of Steering Committee (2012 - Present)
  • Langmuir, Member of Editorial Advisory Board (2012 - Present)
  • Langmuir, Editorial Advisory Board Member (2012 - Present)
  • Langmuir, Member of Editorial Advisory Board (2012 - Present)
  • Science, Nature Nanotechnology, JACS, Angew Chem, Nano Letters, ACS Nano, etc., Reviewer (2012 - Present)
  • Biophysics Joint Biodesign-Physics Faculty Search Committee, Member (2011 - Present)
  • International Meeting in DNA Cumputing and Molecular Programming, Member of Steering Committee (2011 - Present)
  • International Meeting in DNA Cumputing and Molecular Programming, Member of Steering Committee (2011 - Present)
  • Symposium "DNA nanotechnology" MRS Spring Meeting 2012, Co-Chair (2011 - Present)
  • Symposium "DNA nanotechnology" MRS Spring Meeting 2012, Co-Chair (2011 - Present)
  • Symposium "DNA nanotechnology" MRS Spring Meeting 2012, Co-organizer (2011 - Present)
  • Symposium in Honor of Ned Seeman, Snowbird, Utah, April 11 (2011)., Organizer and Chair (2011 - Present)
  • Army Research Office, Ad hoc reviewer (2011 - Present)
  • Center for Integrated Nanotechnologies, Los Alamos National Laboratory, Invited member of user proposal review panel (2011 - Present)
  • International Conference on Bio-Inspired Computing: Theory and Applications (BIC-TA), Member of Steering Committee (2011 - Present)
  • National Science Foundation, Panelist and Ad Hoc Reviewers (2011 - Present)
  • Science, Nature Nanotechnology, JACS, Angew Chem, Nano Letters, ACS Nano, etc., Reviewer (2011 - Present)
  • Symposium in Honor of Ned Seeman, Organizer and Chair (2011 - Present)
  • biological nanostructures facility at the Molecular Foundry in Lawrence Berkeley Laboratory., Invited member of user proposal review panel (2011 - Present)
  • Committe for Graduate Program, Member (2010 - Present)
  • Departmental Graduate Program Committee, Member (2010 - Present)
  • Departmental Graduate Program Committee, Member (2010 - Present)
  • International Conference on Bio-Inspired Computing: Theory and Applications (BIC-TA), Member of Steering Committee (2010 - Present)
  • Workshop on "Bio-directed assembly", Keystone, CO, May 18-19 (2010)., Chair and organizer (2010 - Present)
  • Session on "DNA Nanomachines in Vitro and Inside Living Cells", 54th Annual Biophysical Society Meeting, San Francisco, CA, Feb. 20-24 (2010)., Chair (2010 - Present)
  • Angew Chem Int Ed, Reviewer (2010 - Present)
  • J. Am. Chem. Soc, Reviweer (2010 - Present)
  • Nature, Science, Nature Nanotechnology, Nature Materials, ACS Nano, Nano Letters, Small, etc., Reviewer (2010 - Present)
  • Biodesign Institute Personnel Committee, Member (2009 - Present)
  • Biodesign Institute Personnel Committee, Member (2009 - Present)
  • Biodesign Institute Personnel Committee, Member (2009 - Present)
  • Personnel Committee, Member (2009 - Present)
  • Session on "DNA Nanomachines in Vitro and Inside Living Cells", 54th Annual, Chair (2009 - Present)
  • Angew Chem Int Ed, reviewer (2009 - Present)
  • DNA Nanotechnology Workshop, Co-organizer (2009 - Present)
  • DOE, reviewer (2009 - Present)
  • DOE, reviewer (2009 - Present)
  • Departmental Seminar Committee, Chair of the committee (2009 - Present)
  • International Workshop on DNA-based nanotechnology:, Co-organizer (2009 - Present)
  • J. Am. Chem. Soc., Reviewer (2009 - Present)
  • Nano Letters, Reviewer (2009 - Present)
  • National Science Foundation, Proposal reviewer (2009 - Present)
  • National Science Foundation, Proposal reviewer (2009 - Present)
  • Nature, reviewer (2009 - Present)
  • Nature Chemistry, Reviewer (2009 - Present)
  • Nature Materials, reviewer (2009 - Present)
  • Nature Nanotechnology, Reviewer (2009 - Present)
  • Science, Reviewer (2009 - Present)
  • Nature, Reviewer (2008 - Present)
  • Science, Reviewer (2008 - Present)
  • the 15th International meeting for DNA computing, Program Committee member (2008 - Present)
  • International Workshop on DNA-based nanotechnology, co-chair (2008 - Present)
  • NCAA self-study committee, member (2008 - Present)
  • Departmental Seminar Committee, Chair (2008 - Present)
  • Track on Self-assembled DNA nanostructures, Fifth Conference on Foundations OF Nanoscience: Self-assembled Architectures and Devices (FNANO08), Snowbird, Utah, (2008)., Program track co-chair (2008 - Present)
  • Research Cooperation, Proposal reviewer (2006 - Present)
  • Departmental Seminar Committee, Member (2006 - Present)
  • American Chemical Society Petroleum Fund, Proposal reviewer (2006 - Present)
  • National Science Foundation, Proposal reviewer (2006 - Present)
  • Journal of American Chemical Society, Reviewer (2006 - Present)
  • Journals of: PNAS, Small, Nanotechnology, Advanced Materials, Chem. Commun, Reviewer (2006 - Present)
  • Chemistry of Materials, Reviewer (2005 - Present)
  • Nano Letter, Reviewer (2005 - Present)
  • Departmental Septannual Review, Member (2005 - Present)
  • Proc. Natl. Acad. Sci, Reviewer (2005 - Present)
  • Small, Reviewer (2005 - Present)
  • ACS petroleum fund, Ad Hoc Reviewer (2005 - Present)
  • J. Am. Chem Soc, Reviewer (2005 - Present)
  • The Seventh International Meeting on Scanning Probe Microscopy, Cancun, Mexico, Session Chair (2005 - Present)
  • Angew Chem. Int. Ed, Reviewer (2005 - Present)
  • Biomacromolecules, Reviewer (2005 - Present)
  • National Science Foundation, Panelist (2005 - Present)
  • Program Committee, The 11th International meeting for DNA computing, London, Ontario, Canada, Member (2005 - Present)
  • Advanced Material, Reviewer (2005 - Present)
  • Scientific advisory board, Nanoscience Technologies Inc, Member (2004 - Present)
  • International Society for Nanoscale Science, Computation and Engineering, President (2013 - 2015)
  • Department of Energy, Proposal reviewer (2013 - 2013)
  • International Meeting on DNA Computing and Molecular Programming, Member of Steering Committee (2013 - 2013)
  • National Science Foundation, Proposal reviewer (2013 - 2013)
  • Science, Nature Chemistry, Nature Communications, JACS, Angew Chem etc., Reviewer (2013 - 2013)
  • 19th International Meeting in DNA Computing and Molecular Programming, Chair of the Organizing Committee (2013 - 2013)
  • Departmental Seminar Committee, Chair (2009 - 2010)
  • Program Committee , 13th International meeting for DNA computing, Memphis, Co-Chair (2007 - 2007)
  • Program Committee , 12th International meeting for DNA computing, Seol, Korea, Member (2006 - 2006)
  • Faculty Search Committee for biophysical theory position, Member (2005 - 2006)
  • Program Committee , 11th International meeting for DNA computing, London, Ontario, Canada, Member (2005 - 2005)
  • The Seventh International Meeting on Scanning Probe Microscopy, Cancun, Mexico, Session Chair (2005 - 2005)
  • National Institute of Health, Panelist (2004 - 2004)
  • Program Committee , 10th international meeting on DNA-based Computers, Milano, Italy, Member (2004 - 2004)
  • Program Committee , 8th Int'l Conference on Knowledge-Based Intelligent Information & Engineering Systems, Wellington, New Zealand, Member (2004 - 2004)
  • Angew. Chem. Int. Ed, Reviewer (2004)
  • J. Am. Chem. Soc, Reviewer (2004)
  • NIH/Nanoscience and Nanotechnology in Biology and Medicine, Review Panelist (2004)
  • NSF/Nanotechnology Exploratory Research Review Panel, Review Panelist (2004)
  • Science, Reviewer (2004)
  • the 10th international meeting on DNA-based Computers, Milano, Italy, Program Committee member (2004)
  • Reviewer (Present)
  • 3rd International Conference on “Smart Materials,Structures and Systems”--Symposium E: “Mining Smartness from Nature”, International Advisory Board Member (Present)
  • Natural Computing: Special Issue: DNA computing conference 2007, Springer, guest co-editor (Present)
  • the 12th International meeting for DNA computing, Program committee member (Present)
  • the 13th International meeting for DNA computing, Program committee co-chair (Present)
Expertise Areas: 
Analytical Chemistry
Biochemistry
Inorganic Chemistry
Materials Science
Energy
Nanoscience