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Rajeev Misra

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School of Life Sciences
Professor
Faculty, TEMPE Campus, Mailcode 4501
Biodesign Center for Fundamental & Applied Microbiomics
Professor
Faculty, TEMPE Campus, Mailcode 4501
Biography: 

Misra is a microbial geneticist who studies how proteins, synthesized in the cytoplasm, are targeted to the bacterial outer membrane. His research focuses on a particular class of outer membrane proteins that form beta-barrels and mediate solute transport and protein assembly. A central component of the assembly machinery is conserved in all Gram-negative bacteria and in mitochondria and chloroplasts of eukaryotes, the two organelles of bacterial origin.

A second project in his laboratory examines the mechanism of drug resistance, with an emphasis on the major multi-drug efflux pump system of clinical relevance. His research employs classical genetics and molecular biology approaches to investigate membrane biology and drug resistance.

CV
Binary Data Curriculum Vitae
Education: 

PhD Adelaide University, Australia

Publications: 
  • Weeks, J.W., V.N. Bavro, and R. Misra. 2014. Genetic assessment of the role of AcrB β-hairpins in the assembly of the TolC-AcrAB multidrug efflux pump of Escherichia coli. Mol. Microbiol. 91:965-975.
  • Misra, R., Stikeleather, R., and R. Gabriele. 2015. In vivo roles of BamA, BamB and BamD in the biogenesis of BamA, a core protein of the β-barrel assembly machine of Escherichiacoli. J. Mol. Biol. 427:1061-1074.
  • Misra, R., K.D. Morrison, H.-J. Cho, T. Khuu. 2015. Importance of real-time assays to distinguish multidrug efflux pump inhibiting and Outer Membrane destabilizing activities in Escherichia coli. J. Bacteriol. 197:2479-2488.
  • Misra, R. 2015. Entry and exit of bacterial outer membrane proteins. Trends Microbiol. http://dx.doi.org/10.1016/j.tim.2015.07.001.
  • Soparkar, K., A.D. Kinana, J.W. Weeks, K.D. Morrison, H. Nikaido, and R. Misra. 2015. Reversal of the drug binding pocket defects of the AcrB multidrug efflux pump protein of Escherichia coli. J. Bacteriol. doi:10.1128/JB.00547-15.

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  • Misra, R., R. Stikeleather, and R. Gabriele. In vivo roles of BamA, BamB and BamD in the biogenesis of BamA, a core protein of the ß-barrel assembly machine of Escherichia coli. Journal of Molecular Biology (2014).
  • Weeks, J. V. Bavro, and R. Misra. Genetic assessment of the role of AcrB ß-hairpins in the assembly of the TolC-AcrAB multidrug efflux pump of Escherichia coli. Molecular Microbiololy (2014).
  • Leiser, O.P., E.S. Charlson, H. Gerken, and R. Misra. Reversal of the delta-degP phenotypes by a novel rpoE allele of Escherichia coli K-12. PLoS One (2012).
  • Leonard-Rivera, M., and R. Misra. Conserved residues of the putative L6 loop of Escherichia coli BamA play a critical role in the assembly of beta-barrel outer membrane proteins, including BamA itself. Journal of Bacteriology (2012).
  • Misra, R. Assembly of the ß-barrel outer membrane proteins in Gram-negative bacteria, mitochondria and chloroplasts. ISRN Molecular Biology (2012).
  • Tellez, R. Jr., and R. Misra. Substitutions in the BamA ß-barrel domain overcome the conditional lethal phenotype of adelta-bamB delta-bamE strain of Escherichia coli. Journal of Bacteriology (2012).
  • Workman, P., K. Heide, N. Giuliano, N. Lee, J. Mar, P. Vuong, D. Bennion, and R. Misra. Genetic, biochemical and molecular characterization of the BamA POTRA 1 domain of Escherichia coli. Journal of Bacteriology (2012).
  • Rajeev Misra. Assembly of the ß-barrel outer membrane proteins in Gram-negative bacteria, mitochondria and chloroplasts. (2012).
  • Tellez, R. Jr., and R. Misra. Substitutions in the BamA ß-barrel domain overcome the conditional lethal phenotype of a ?bamB ?bamE strain of Escherichia coli. Journal of Bacteriology (2011).
  • Vuong, P., and R. Misra. Guide to genome-wide bacterial transcription factor binding site prediction using OmpR as model. Selected Works in Bioinformatics (2011).
  • Bennion, D., E.S. Charlson, E. Coon, and R. Misra. Dissection of ß-barrel outer membrane protein assembly pathways through characterizing BamA POTRA 1 mutants of Escherichia coli. Molecular Microbiology (2010).
  • Gerken, H., and R. Misra. MzrA-EnvZ interactions in the periplasm influence the EnvZ-OmpR two-component regulon. Journal of Bacteriology (2010).
  • Gerken, H., O. Leiser, D. Bennion, and R. Misra. Involvement and necessity of the CpxAR two-component regulon in the event of aberrant assembly of ß-barrel outer membrane proteins. Molecular Microbiology (2010).
  • Weeks, J.W., T. Celaya-Kolb, S. Pecora, and R. Misra. AcrA suppressor alterations reverse the drug hypersensitivity phenotype of a TolC mutant by inducing TolC aperture opening. Molecular Microbiology (2010).
  • Gerken, H., E.S. Charlson, E.M. Cicirelli, L.J. Kenney, and R. Misra. MzrA, a novel modulator of the EnvZ/OmpR two-component regulon. Mol. Microbiol (2009).
  • Masi, M., G. Duret, A.H. Delcour, and R. Misra. Folding and trimerization of signal sequence-less mature TolC in the cytoplasm of Escherichia coli. Microbiology (2009).
  • Misra, R., and V.N. Bavro. Assembly and transport mechanism of tripartite drug efflux systems. Biochim. Biophys. Acta (2009).
  • Bavro, V.N., Z. Pietras, N. Furnham, L. Pérez-Cano, J. Fernández-Recio, X. Yuan Pei, R. Misra and B. Luisi. Channel opening and allostery in a bacterial drug efflux machine. Molecular Cell (2008).
  • Vuong, P., D. Bennion, J. Mantei, D. Frost, and R. Misra. Analysis of YfgL and YaeT Interactions through Bioinformatics, Mutagenesis, and Biochemistry. Journal of Bacteriology (2008).
  • G. Perry, Anne Stone, N. Dominy, K. Claw, A. Lee, J. Werner, F. Villanea, Rajeev Misra, R. Misra, C. Lee. Diet and the evolution of amylase gene copy number variation among human populations. Nature Genetics (2007).
  • Rajeev Misra. First glimpse of the crystal structure of YaeT’s POTRA domains. Chemical Biology (2007).
  • Rajeev Misra, J. Mountain, R. Misra, N. Carter, C. Lee, A. Stone., G. Perry, N. Dominy, K. Claw, A. Lee, H. Fiegler, R. Redon, J. Werner, F. Villanea. Diet and the evolution of copy number variation of the human amylase gene. Nature Genetics (2007).
  • Rajeev Misra, M. Masi, P. Vuong, M. Humbard, K. Malone, R. Misra. Initial steps of colicin E1 import across the outer membrane of Escherichia coli. Journal of Bacteriology (2007).
  • J Malinverni, J Werner, S Kim, J Sklar, D Kahne, Rajeev Misra, T Silhavy. YfiO stabilizes the YaT complex and is essential for outer membrane protein assembly in E. coli. Molecular Microbiology (2006).
  • M Castillo-Keller, P Vuong, Rajeev Misra. Novel mechanism of Escherichia coli porin regulation. Journal of Bacteriology (2006).
  • S Charlson, J Werner, Rajeev Misra. Differential effects of yfgL mutation on the biogenesis of Escherichia coli outer membrane proteins and lipopolysaccharide. J. Bacteriol (2006).
  • German, G J (Author) ,Misra, Rajeev (Author) ,Kropinski, A (Author) . The T1-like bacteriophages. The Bacteriophages (2006).
  • J Werner, Rajeev Misra. YaeT (Omp85) affects the assembly of lipid-dependent and lipid-independent outer membrane proteins of Escherichia coli. Molecular Microbiology (2005).
  • A Augustus, T Celaya, F Husain, M Humbard, Rajeev Misra. Antibiotic sensitive TolC mutants and their suppressors. Journal of Bacteriology (2004).
  • F Husain, M Humbard, Rajeev Misra. Interaction between the TolC and AcrA proteins of a multidrug efflux system of Escherichia coli. Journal of Bacteriology (2004).
  • H Gerken, Rajeev Misra. Genetic evidence for AcrB-dependent functional interactions between TolC and AcrA proteins of a major antibiotic efflux pump of Escherichia coli. Molecular Microbiology (2004).
  • J Werner, A Augustus, Rajeev Misra. Assembly of TolC, a structurally unique and multifunctional outer membrane protein of Escherichia coli K-12. Journal of Bacteriology (2003).
  • Maria CastilloKeller, Rajeev Misra. Protease-deficient DegP suppresses lethal effects of a mutant OmpC protein by its capture. Journal of Bacteriology (2003).
  • C Landers, O Cohavy, Rajeev Misra, H Yang, Y Lin, J Braun, S Targan. Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto- and microbial antigens. Gastroenterology (2002).
  • A Kloser, J Reading, T McDermott, R Stidham, Rajeev Misra. Intragenic suppressors of an OmpF assembly mutant and assessment of the roles of various OmpF residues in assembly through informational suppressors. J. Bacteriol (2001).
  • G German, Rajeev Misra. The TolC protein of Escherichia coli serves as a receptor for the newly characterized TLS bacteriophage. J. Mol. Biol (2001).
  • H Vakharia, G German, Rajeev Misra. Isolation and characterization of Escherichia coli tolC mutants defective in secreting enzymatically active a-hemolysin. J. Bacteriol (2001).
  • O Cohavy, D Bruckner, L Gordon, Rajeev Misra, M Eggena, S Targan, J Braun. Colonic bacteria express an ulcerative colitis pANCA-ralated protein epitope. Infect. Imm (2000).
  • Rajeev Misra, M CastilloKeller, M Deng. Overexpression of protease deficient DegPS210A rescues the lethal phenotype of Escherichia coli OmpF assembly mutants in a degP background. J. Bacteriol (2000).
Research Activity: 
Fall 2021
Course NumberCourse Title
BIO 495Undergraduate Research
MBB 495Undergraduate Research
MIC 495Undergraduate Research
MBB 499Individualized Instruction
MIC 501Foundations in Microbiology
Spring 2021
Course NumberCourse Title
MIC 442Bacterial Genetics Laboratory
MBB 493Honors Thesis
MIC 493Honors Thesis
MIC 495Undergraduate Research
MBB 495Undergraduate Research
BIO 495Undergraduate Research
Fall 2020
Course NumberCourse Title
MIC 360Bacterial Physiology
MIC 492Honors Directed Study
MIC 495Undergraduate Research
BIO 495Undergraduate Research
MBB 495Undergraduate Research
MBB 499Individualized Instruction
MIC 501Foundations in Microbiology
Summer 2020
Course NumberCourse Title
MIC 495Undergraduate Research
Spring 2020
Course NumberCourse Title
MIC 442Bacterial Genetics Laboratory
BIO 492Honors Directed Study
MBB 493Honors Thesis
MIC 493Honors Thesis
MIC 495Undergraduate Research
MBB 495Undergraduate Research
BIO 495Undergraduate Research
Fall 2019
Course NumberCourse Title
MIC 360Bacterial Physiology
MIC 492Honors Directed Study
MIC 495Undergraduate Research
BIO 495Undergraduate Research
MBB 495Undergraduate Research
MBB 499Individualized Instruction
MIC 501Foundations in Microbiology
Summer 2019
Course NumberCourse Title
MIC 495Undergraduate Research
Spring 2019
Course NumberCourse Title
MIC 442Bacterial Genetics Laboratory
MBB 493Honors Thesis
MIC 493Honors Thesis
MIC 495Undergraduate Research
MBB 495Undergraduate Research
BIO 495Undergraduate Research
Fall 2018
Course NumberCourse Title
MIC 360Bacterial Physiology
MIC 492Honors Directed Study
BIO 495Undergraduate Research
MBB 495Undergraduate Research
MIC 495Undergraduate Research
MBB 499Individualized Instruction
Summer 2018
Course NumberCourse Title
MIC 495Undergraduate Research
Spring 2018
Course NumberCourse Title
MIC 442Bacterial Genetics Laboratory
MBB 493Honors Thesis
MIC 493Honors Thesis
MIC 495Undergraduate Research
MBB 495Undergraduate Research
BIO 495Undergraduate Research
Fall 2017
Course NumberCourse Title
MIC 360Bacterial Physiology
MIC 492Honors Directed Study
BIO 495Undergraduate Research
MBB 495Undergraduate Research
MIC 495Undergraduate Research
MBB 499Individualized Instruction
Summer 2017
Course NumberCourse Title
MIC 495Undergraduate Research
Spring 2017
Course NumberCourse Title
MIC 442Bacterial Genetics Laboratory
MBB 493Honors Thesis
MIC 493Honors Thesis
MIC 495Undergraduate Research
MBB 495Undergraduate Research
BIO 495Undergraduate Research
Presentations: 
  • Rajeev Misra. Outer Membrane Protein Assembly and Envelope Stress: two sides of the same coin. Department of Microbiology Seminar, University of Illinois, Urbana-Champaign (Oct 2014).
  • Rajeev Misra. In vivo Investigation of Bacterial Multidrug Efflux Pumps. University of Kentucky, Department of Chemistry (Sep 2014).
  • Rajeev Misra. Biogenesis of BamA (Omp85), a core protein of the ß-barrel assembly machine of Gram negative bacteria, mitochondria and chloroplasts. Wind River Conference on Prokaryotic Biology, Estes Park, CO (Jun 2014).
  • Hyun Jae Cho and Rajeev Misra. Mutational activation of drug efflux pump genes in Escherichia coli. Arizona/Nevada Chapter of American Society for Microbiology (Los Vegas, Nevada) (Apr 2014).
  • Keith Morrison, Rajeev Misra and Lynda Williams. Mechanistic basis of antibacterial activities of clays. Arizona/Nevada Chapter of American Society for Microbiology (Los Vegas, Nevada) (Apr 2014).
  • Rajeev Misra. Multidrug Resistance Bugs: why should we care?. Karcher/Barton Seminar, Department of Chemistry and Biochemistry, University of Oklahoma (Apr 2014).
  • Rajeev Misra. Biogenesis of BamA (Omp85), a core protein of the ß-barrel assembly machine of Gram negative bacteria, mitochondria and chloroplasts. Departmental seminar, Chemistry and Biochemistry, University of Oklahoma, Noman (Apr 2014).
  • Ryan Stikeleather and Rajeev Misra. Biochemical Analysis of the Highly Conserved ß-Barrel Assembly Machine. Arizona/Nevada Chapter of American Society for Microbiology (Tucson) (Apr 2013).
  • Eric Linden, Dan Muongpack and Rajeev Misra. The Functional Analysis of TolC-AcrAB Tripartite Efflux and Operations of Channel Opening/Closing. Arizona/Nevada Chapter of American Society for Microbiology (Tucson) (Apr 2013).
  • Rajeev Misra. Suppressors: easy to isolate, not always easy to interpret. Meeting on Genetic Approaches to Understanding Complex Biological Problems (Mar 2013).
  • Jon Weeks and Rajeev Misra. Genetic interactions among the antibiotic efflux components. Arizona/Nevada Chapter of American Society for Microbiology (at ASU) (Apr 2012).
  • Maggie Leonard-Rivera and Rajeev Misra. A conserved mechanism of beat-barrel outer membrane protein assembly from bacteria to human. Arizona/Nevada Chapter of American Society for Microbiology (at ASU) (Apr 2012).
  • Hosnah Maududi, Jon Weeks and Rajeev Misra. Functional assembly of a major drug efflux system in Escherichia coli. Arizona/Nevada Chapter of American Society for Microbiology (at ASU) (Apr 2012).
  • Misra, R. (Attended the meeting). Gordon Research Conference on Protein Secretion Across Cell Membranes (Apr 2012).
  • Rajeev Misra, Owen P. Leiser, Emily S. Charlson, and Henri G. Gerken. A novel sigma factor gene allele overcomes the conditional lethal phenotype of a strain lacking the major periplasmic protease of Escherichia coli. 55th Wind River Conference on Prokaryotic Biology, CO (Jun 2011).
  • Jon Weeks and Rajeev Misra. Genetic Analysis of AcrAB-TolC, the multidrug Efflux Complex of E coli. Annual General American Society for Microbiology, New Orleans (May 2011).
  • Owen Leiser and Rajeev Misra. Envelope Homeostasis in Escherichia coli. Arizona/Nevada Chapter ASM (Northern Arizona University, Falgstaff, AZ) (Apr 2011).
  • Rene Tellez Jr and Rajeev Misra. Conditional Lethal Phenotype of ?bamB ?bamE is Overcome by Alterations in the ß-barrel Domain of BamA. Arizona/Nevada Chapter ASM (Northern Arizona University, Falgstaff, AZ) (Apr 2011).
  • Rajeev Misra and Owen Leiser. Novel aspects of envelope stress response. Gordon Research Conference on Protein Secretion Across the Membranes, Galveston (Mar 2011).
  • Rajeev Misra. Transport across membranes: Multiple drug resistance, mechanisms and new tools. 462th WE Heraeus Seminar, Jacobs University Bremen, Germany (Jul 2010).
  • Rajeev Misra, Henri Gerken, Owen Leiser and Drew Bennion. New insights into bacterial envelope stress response. Gordon Research Conference on Bacterial Cell Surfaces, New Hamshire (Jun 2010).
  • Jon Weeks and Rajeev Misra. Genetic Analysis of the Role of TolC's Periplasmic Turn 1 in Antibiotic Efflux. Molecular Genetics of Bacteria and Phage (Madison WI) (Aug 2009).
  • Qwen Leiser and Rajeev Misra. Envelope Stress Response in Escherichia coli. Molecular Genetics of Bacteria and Phage (Madison WI): (Aug 2009).
  • Jon Weeks and Rajeev Misra. Genetic Analysis of the Role of TolC's Periplasmic Turn 1 in Antibiotic Efflux. Annual General American Society for Microbiology, Philadelphia (May 2009).
  • Owen Leiser and Rajeev Misra. Relief of Envelope Stress in Escherichia coli. Arizona/Nevada Chapter ASM (Tucson AZ) (Mar 2009).
  • Jon Weeks and Rajeev Misra. Investigation of the Role of AcrB Hairpin Loops in Antibiotic Efflux, presentation. Arizona/Nevada Chapter ASM (Tucson AZ) (Mar 2009).
  • H. Gerken, E. Charlson, R. Misra. A novel protein, MzrA, links the two two-component envelope regulatory systems of Escherichia coli. Molecular Genetics of Bacteria and Phages, Cold Spring Harbor, NY (Aug 2008).
  • O.P. Leiser, and R. Misra. Stress responses and outer membrane biogenesis in E coli. Molecular Genetics of Bacteria and Phages, Cold Spring Harbor, NY (Aug 2008).
  • R. Misra, H. Gerken, E. Charlson. A novel protein, MzrA, links the two two-component envelope regulatory systems of Escherichia coli. Gordon Research Conference (Jun 2008).
  • J. Weeks, and R. Misra. Opening and closing of TolC's aperture during antibiotic efflux. West Coast Biological Sciences Undergraduaet Research Conferences (Apr 2008).
  • J. Weeks and R. Misra. Import of colicin E1. American Society for Microbiology, AZ and NV branch (Apr 2008).
  • Gerken, H., Charlson, E., Misra, R., Misra, Rajeev. Suppressor Analysis of Escherichia coli Lacking Periplasmic Protease DegP and Assembly Factor YfgL. Molecular Genetics of Bacteria and Phages (Aug 2007).
  • Leiser, O., Misra, Rajeev. Role of YfgC in Outer Membrane Biogenesis and Periplasmic Stress Response in Escherichia coli. Molecular Genetics of Bacteria and Phages (Aug 2007).
  • Masi, M., Misra, R., Misra, Rajeev. Signal sequenceless TolC in Escherichia coli: in vivo biogenesis, in vitro activity and suppressor analysis. Molecular Genetics of Bacteria and Phages (Aug 2007).
  • Misra, Rajeev. Identification of YfgL residues that are important for interaction with YaeT. Molecular Genetics of Bacteria and Phages (Aug 2007).
  • Treuer, R., Weeks, J., Misra, R., Misra, Rajeev. Interaction between TolC and AcrA Proteins of the Major Antibiotic Efflux System of Escherichia coli. Molecular Genetics of Bacteria and Phages (Aug 2007).
  • Masi, M, Vuong, P, Humbard, M, Malone, K, Misra, Rajeev. Initial steps of colicin E1 import across the outer membrane of Escherichi coli. Gordon Conference of Bacterial Cell Surfaces (Jun 2007).
  • Al-Khatib, S, Husian, F, Misra, Rajeev. Genetic analysis of the role of AcrB hairpin loop in antibiotic efflux. American Society for Microbiology Annual Meeting, AZ-NV Branch (Feb 2006).
  • Charlson, E, Werner, J, Coon, E, Misra, Rajeev. Selective role of YfgL in Escherichia coli outer membrane protein biogenesis. American Society for Microbiology Annual Meeting, AZ-NV Branch (Feb 2006).
  • Kob, T, Pecora, S, Treuer, R, Misra, Rajeev. Importance of TolC periplasmic turns in protein-protein interactions. American Society for Microbiology Annual Meeting, AZ-NV Branch (Feb 2006).
  • CastilloKeller, M, Wong, F, Misra, Rajeev. A novel mechanism of regulating porin gene expression in Escherichia coli. Molecular Genetics of Bacteria and Phages (Aug 2005).
  • Charlson, E, Werner, J, Coon, E, Misra, Rajeev. Parallel but converging pathways of outer membrane protein assembly in Escherichia coli. Molecular Genetics of Bacteria and Phages (Aug 2005).
  • Kolb, T, Husain, F, Pecora, S, Al-Khatib, S, Misra, Rajeev. Importance of TolC turns and AcrB hairpins in protein-protein interactions. Molecular Genetics of Bacteria and Phages (Aug 2005).
  • Werner, J, Charlson, E, Coon, E, Misra, Rajeev. New factors in Escherichia coli outer membrane assembly. Gordon Research Conference (Jun 2005).
  • Pecora, S, Celaya, T, Husain, F, Misra, Rajeev. Loops and turns of TolC, an outer membrane component of the bacterial antibiotic efflux pump. American Society for Microbiology, Arizona-Navada Branch (Apr 2005).
  • Charlson, E, Coon, E, Werner, J, Misra, Rajeev. Genetics of outer membrane protein assembly in Escherichia coli. American Society for Microbiology (Apr 2005).
  • Husain, Fasahath, Gerken, Henri, Misra, Rajeev. Interaction between TolC and AcrA components of a multidrug efflux pump of E. coli. Molecular Genetics of Bacteria and Phages Annual Meeting (Jul 2004).
  • Werner, John, Misra, Rajeev. The essential E. coli protein YaeT is involved in the assembly of outer membrane proteins. Molecular Genetics of Bacteria and Phages Annual Meeting (Jul 2004).
  • Werner, John, Misra, Rajeev. Unique assembly pathway of a multifunctional TolC protein of E. coli. American Society for Microbiology Annual Meeting (May 2004).
  • Husain, Fasahath, Gerken, Henri, Misra, Rajeev. Suppression of the antibiotic sensitivity phenotype of mutant TolC proteins by mutations that alter AcrA structure or its expression. American Society for Microbiology Annual Meeting (May 2004).
  • CastilloKeller, Maria, Misra, Rajeev. A samll regulatory RNA affects expression of porin expression in Escherichia coli. American Society for Microbiology Annual Meeting (May 2004).
  • Misra, Rajeev. Assembly of a multifunctional outer membrane protein. Molecular Genetics of Bacteria and Phages (Aug 2003).
  • Misra, Rajeev. The role TolC in antibiotic efflux and colicin import. Molecular Genetics of Bacteria and Phages (Aug 2003).
  • Misra, Rajeev. The T1-like TolC & LPS-specific (TLS) pahge genome & the evolution and taxonomy of virulent phages. American Society for Microbiology (May 2003).
  • Misra, Rajeev. Two novel multicopy suppressors rescue mutant OmpC lethlaity. American Society for Microbiology (May 2003).
Service: 
  • Microbiome Faculty Search Committee, Member (2014 - Present)
  • National Science Foundation, Graduate Research Fellowship, Genomics, Proteomics and Bioinformatics, Panel member (2014 - Present)
  • Biotechnology and Biological Sciences Research Council, United Kingdom, Expert Reviewer (2014 - Present)
  • American Society for Microbiology, Arizona and Southern Nevada Branch, Student talks Judge (2014 - Present)
  • NIH, Transformative Research Award, Expert Reviewer (2014 - Present)
  • National Science Foundation, Graduate Research Fellowship, Microbiology Panel, Panel member (2013 - Present)
  • Standing Review Committee, Office of Knowledge Enterprise Development, Member (2013 - Present)
  • Standing Review Committee, Office of Knowledge Enterprise Development, Member (2013 - Present)
  • NIH, Special Emphasis Panel: Topics in Drug Resistance, Member (2013 - Present)
  • NIH, Special Emphasis Panel: collaborations for macromolecular interactions in cells, Expert Reviewer (2013 - Present)
  • Nature, PNAS(USA), Genetics, Expert Reviewer (2013 - Present)
  • School of Life Sciences Undergraduate Committee, Member (2013 - Present)
  • Cellular and Molecular Biosciences Faculty Personnel Committee, Committee member (2012 - Present)
  • Cellular and Molecular Biosciences Faculty Personnel Committee, Committee member (2012 - Present)
  • Cellular and Molecular Biosciences Faculty Personnel Committee, Committee member (2012 - Present)
  • Current Microbiology; Biochemistry; PLoS ONE, Membrane Molecular Biology, Reviewer (2012 - Present)
  • Molecular Microbiology, Editorial Board Member (2012 - Present)
  • NIH, IDM-A 80S (Bacterial Pathogenesis Focus), Panel Member (2011 - Present)
  • PLoS ONE, Academic Editor (2011 - Present)
  • PLoS ONE, Academic Editor (2011 - Present)
  • National Science Foundation, Grant Proposal Reviewer (2011 - Present)
  • Pasteur Institute, Grant Reviewer (2011 - Present)
  • NIH, Special Emphasis Panel, Bacterial Pathogenesis (R21 proposals), Panel Member (2011 - Present)
  • DFG, Germany, Grant Proposal Reviewer (2011 - Present)
  • Wellcome Trust, UK, Grant Proposal Reviewer (2011 - Present)
  • Mol Microbiol, J. Bact., JBC, PLoS ONE, FASEB, Microbiology, AEM, Chem & Biol (Cell), Expert Reviewer (2011 - Present)
  • Microbiology Graduate Program, Member (2008 - Present)
  • Microbiology Graduate Program, Member (2008 - Present)
  • Microbiology Graduate Program, Executive Committee Member (2008 - Present)
  • Microbiology Graduate Program Committee, Member (2008 - Present)
  • Microbiology, Expert Reviewer (2007 - Present)
  • Antimicrobial and Chemptherapy, Reviewer (2006 - Present)
  • Molecular Microbiology, Expert reviewer (2006 - Present)
  • Executive Committee/School of Life Sciences, Member (2005 - Present)
  • Nature, Reviewer (2005 - Present)
  • Bacterial Pathogenesis Faculty Search Committee, Member (2005 - Present)
  • National Graduate Fellowship Award Panel, National Science Foundation, Panel Member (2005 - Present)
  • CMB Personnel Committee, Member (2004 - Present)
  • Molecular and Cellular Biology Colloquium, Organizer (2004 - Present)
  • Mycobacterium tuberculosis Faculty Search Committee, Member (2004 - Present)
  • Journal of Bacteriology, Editorial Board Member (2000 - 2015)
  • Molecular Microbiology, Editorial Board Member (2012 - 2014)
  • PLoS ONE, Academic Editor (2011 - 2014)
  • NIH, Special Emphasis Panel, Bacterial Pathogenesis, Panel Member (2011 - 2014)
  • American Society for Microbiology, Arizona and Southern Nevada Branch, President (2012 - 2013)
  • American Society for Microbiology, Arizona and Southern Nevada Branch, President (2012 - 2013)
  • Molecular Microbiology, Editorial Board Member (2012 - 2013)
  • PLoS ONE, Academic Editor (2011 - 2013)
  • Journal of Bacteriology, Editorial Board Member (2000 - 2012)
  • Journal of Bacteriology, Member Editorial Board (2000 - 2012)
  • Quality of Instruction, Member (2009 - 2012)
  • Microbiology Graduate Program, Member (2008 - 2012)
  • NIH, Special Emphasis Panel, Bacterial Pathogenesis, Panel Member (2011 - 2011)
  • Quality of Instruction, Member (2009 - 2011)
  • Microbiology Graduate Program, Member (2008 - 2011)
  • Applied and Environmental Microbiology, Reviewer (2010 - 2010)
  • BMC Microbiology, Reviewer (2010 - 2010)
  • Biochemistry, Reviewer (2010 - 2010)
  • Genetics, Reviewer (2010 - 2010)
  • Molecular Microbiology, Expert Reviewer (2010 - 2010)
  • NIH, Topics in Microbiology, Special Emphasis Panel, Member (2010 - 2010)
  • NIH, Prokaryote Cellular and Molecular Biology Study Section, National Institutes of Health, Permanent Panel Member (2005 - 2010)
  • CMB Personnel Committee, Member (2004 - 2010)
  • Immunology/Virology Faculty Search Committee, Member (2009 - 2010)
  • Microbiology, Expert Reviewer (2009 - 2009)
  • Molecular Microbiology, Expert Reviewer (2009 - 2009)
  • Journal of Bacteriology, Member Editorial Board (2000 - 2009)
  • Executive Committee, Member (2005 - 2008)
  • Graduate Programs, School of Life Sciences, Associate Director (2005 - 2008)
  • Journal of Bacteriology (American Society for Microbiology), Editorial Board Member (2000 - 2006)
  • Research and Training Initiative, Member (2003 - 2005)
  • Evolutionary and Systems Biology Faculty Search Committee, Committee Member (2003 - 2004)
  • NIGMS Study Section MBC II, Ad Hoc Member (2002 - 2004)
  • Journal of Applied and Environmental Microbiology, Peer reviewer (2004)
  • Mutation, Peer reviewer (2004)
  • National Institutes of Health, Ad Hoc Panel Member (MCB-I Section) (2004)
  • National Science Foundation, Ad Hoc Grant Reviewer (2004)
  • Prokaryote Cellular and Molecular Biology Section, National Instiutes of Health, Panel Member (2004)
  • See ASU, Organizer of lab research exhibits (2004)
  • School of Life Sciences Graduate Program Re-organization Committee, Member (2003 - 2003)
  • Microbiology Graduate Program, Director (2000 - 2003)
  • Graduate Program, Director (2003)
  • Jounal of Bacteriology, Editororial Board Member (2003)
  • National Institutes of Health, Ad Hoc grant reviewer (2003)
  • National Science Foundation, Grant reviewer (2003)
  • Seminar Committee, Committee Member (2003)
  • University & College Academic Assembly, Senator (1999 - 2002)
  • NSF Microbial Genetics Panel, Member (2001 - 2001)
  • American Society for Microbiology, Arizona & Nevada branch, President (2000 - 2001)
  • Department Septennial Review Committee, Chair (2000 - 2001)
  • Quality of Instruction Committee, CLAS, Member (1999 - 2001)
  • Virology Search Committee, Member (1999 - 2000)
  • Department's Budget & Personal Committee, Member (1997 - 2000)
Expertise Areas: 
Bacteria
Genetics
Microbes
Microbiology
Proteins