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George Poste

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Chf Scientist & Regent's Prof
Administrative, TEMPE Campus, Mailcode 9908
Chf Scientist & Regent's Prof
Faculty, TEMPE Campus, Mailcode 9908
Biography

Dr. George Poste is Chief Scientist, Complex Adaptive Systems Initiative (CASI) (http://www.casi.asu.edu/), Regents’ Professor and Del E. Webb Chair in Health Innovation at Arizona State University. He assumed this post in February 2009. This program links expertise across the university in research on synthetic biology, ubiquitous sensing and healthcare informatics for personalized medicine. 

He founded the Biodesign Institute at ASU (www.biodesign.asu.edu/) and served as Director for 2003 to 2009. In creating this Institute, Dr. Poste designed and built 400,000 sq. ft. of new facilities, achieved cumulative research funding of $300 million and recruited over 60 faculty, including three members of the National Academies of Science and Engineering.
 
He serves on the Board of Directors of Monsanto (since 2003), Exelixis (since 2004), Caris Life Sciences (since 2005), and the Scientific Advisory Board of Synthetic Genomics (since 2009).  From 1992 to 1999 he was Chief Science and Technology Officer and President, R&D of SmithKline Beecham (SB).  During his tenure at SB he was associated with the successful registration of 31 drug, vaccine and diagnostic products.  In 2004 he was named as ‘R&D Scientist of the Year’ by R&D Magazine, in 2006 he received the Einstein award from the Global Business Leadership Council and in 2009 received the Scrip Lifetime Achievement award voted by the leadership of the global pharmaceutical industry.

He has published over 350 research papers and edited 14 books on pharmaceutical technologies and oncology. He has received honorary degrees in science, law and medicine for his research contributions and was honored in 1999 by HM Queen Elizabeth II as a Commander of the British Empire for his contributions to international healthcare and security.

He is a Fellow of the Royal Society, the Royal College of Pathologists and the UK Academy of Medicine, a Distinguished Fellow at the Hoover Institution, Stanford University and a member of the Council for Foreign Relations.  He served as a member of the Defense Science Board from 2003 to 2009 and Health Board of the US Department of Defense (DoD) and is currently a member of the US Institute of Medicine Board on Global Health.  He has served as a member of Advisory Committees for multiple U.S. Government Agencies in areas of defense, national security and healthcare.

Publications
  • Claudia Acquisti, George Poste, David Curtiss, Sudhir Kumar. Nullomers: really a matter of natural selection?. PLoS ONE (2007).
  • Poste, George Henry. Issues in Bioterrorism and Defense: A View of the Future in Technology Futures and Global Power, Wealth and Conflict. (2006).
  • P Hotez, R Gupta, R Mahoney, George Poste. Incorporating appropriate technology into North American schools of public health. Pan Am J Public Health (2005).
  • George Poste. Statement on Scientific Publication and Security. Nature (2003).
  • Poste, George. Genes and Molecular Medicine. Cambridge (2003).
  • George Poste. Biotechnology, Bioterrorism and Biosecurity. Drug Discovery World (2002).
  • George Poste. Facing Reality in Preparing for Biological Warfare. Health Affairs (2002).
  • George Poste. Molecular diagnostics: a powerful new component of the healthcare value chain. Expert Rev. Mol. Diag (2001).
  • George Poste. Biotechnology and the Evolution of Molecular Medicine. J. Biolaw and Bus Supplement (2000).
  • R Fears, D Roberts, George Poste. Rational or rationed medicine? The promise of genetics for improved clinical practice. BMJ (2000).
  • Hirst, Damient, Burn, Gordon, Poste, George Henry. Revealing Reality Within a Body of Imaginary Things. Essays for Theories, Models, Methods, Approaches, Assumptions and Findings. (2000).
Research Activity
Presentations
  • Poste, George. Biological Threats: New Military Capabilities and Strategic Challenges for National Security. St. Michaels Forum III, US Intelligence Science Board (Oct 2005).
  • Poste, George. The Increasing Importance of the Life Sciences in Defense Technologies and National Security. Cordia Symposium (Oct 2005).
  • Poste, George. Challenges in the Commercial Development of New Drugs and Vaccines. University of Texas Medical Branch Symposium: Facing the Future. Biodefense and Emerging Infectious Diseases (Aug 2005).
  • Poste, George. Countermeasures and Responses to Bioterrror and Emerging Infectious Diseases. (Jun 2005).
  • Poste, George. The Increasing Importance of the Life Sciences in Defense Technologies and National Security. Fubini Lecture, Lincoln Laboratories, MIT (Jun 2005).
  • Poste, George. Bugs Damn Bugs! Where we are Now in the Fight Against Superbugs. Sophie Meeting (Jun 2005).
  • Poste, George. Biotechnology and Computing: The Principal Drivers of Change in Healthcare. Transforming American Healthcare Symposium (Apr 2005).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. Symposium on Global Challenges (Apr 2005).
  • Poste, George. Global Urbanization: Environment, Epidemics and Emerging Infectious Diseases. Keynote address at Landscape Architecture Foundation Symposium, Remaking Metropolis: Global Environmental Challenges to the Urban Landscape (Apr 2005).
  • Poste, George. The Imperative for Curriculum Reform in Medical Education in the Early 21st Century. Gubernatorial Commission on Medical Education (Mar 2005).
  • Poste, George. Preparedness for Bioterrorism and other Mass Casualty Incidents. Keynote Address, Second Annual World Security Conference (Feb 2005).
  • Poste, George. The Strategic Environment for Pharmaceutical and Biotechnology Companies. Healthcare Executive Leadership Forum (Dec 2004).
  • Poste, George. The Urgent Imperative for Innovative R&D Programs to Control the Growing Threat from Infectious Diseases. (Oct 2004).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. Bioterrorism Session with Mayor Bloomberg (Oct 2004).
  • Poste, George. Personalized Medicine. (Sep 2004).
  • Poste, George. Policy, Pricing and Regulatory Issues in the Pharmaceutical Industry. Atlas Ventures Life Sciences Meeting (Sep 2004).
  • Poste, George. The Strategic Environment of Innovation in Healthcare: Evolving New Business Models for Pharmaceutical and Biotechnology Companies. Keynote Address, Global Pharma R&D Summit (Sep 2004).
  • Poste, George. Trends in Biotechnology Implications for Defense Policy and National Security. CSIS Symposium on Technology Frontiers (Jun 2004).
  • Poste, George. Synthetic Biology: Charting Rational Public Policies for the Oversight and Regulation of Vanguard Technologies. (Jun 2004).
  • Poste, George. Risk, Reward and Regulation: Charting Rational Public Policies for Vanguard Technologies. Keynote Address: The International Biotechnology Summit (May 2004).
  • Poste, George. Surviving in a Hazardous World: Risk, Response, Regulation and Responsibility. Keynote Address, Health Protection Agency Anniversary Dinner (Apr 2004).
  • Poste, George. Molecular Medicine: Computing and the Evolution of Healthcare. BioIT Conference (Mar 2004).
  • Poste, George. Genetics and Computing: The Evolution of Molecular Medicine and e.health. HIMSS Conference (Feb 2004).
  • Poste, George. The Past, Present and Future of Pharmacogenomics in Clinical R&D. Keynote address, Life Sciences Pharamcogenomics Conference (Feb 2004).
  • Poste, George. The Biotechnology Sector: Aspirations and Adaptability in Challenging Times. Keynote Address, AdvancePCS Annual Healthcare Conference (Jan 2004).
  • Poste, George. Comprehending Complex Biological Systems: Harnessing Nature's Designs for Innovations in Healthcare, Engineering and Security. CSBI Symposium (Jan 2004).
  • Poste, George. A Look at R&D: Priming the Pump or A Well Run Dry?. (Dec 2003).
  • Poste, George. Systems Biology: The Convergence of Biology, Engineering and Computing. Department of Trade and Industry Symposium (Nov 2003).
  • Poste, George. The Competitive Challenge in Biotechnology. (Nov 2003).
  • Poste, George. The Challenge of Translational Research. Biofunding Summit 2003 (Oct 2003).
  • Poste, George. Genetics, Informatics and the Evolution of Molecular Medicine. Keynote Address, Scientific American Biosilico (Oct 2003).
  • Poste, George. Defining the Pharmaceutical R&D Problem and Prescription for Remedy. Windover Pharmaceutical Strategic Alliances Conference: Deal Making for Pragmatic Times (Sep 2003).
  • Poste, George. Value Creation in Biotechnology. 2003 Atlas Ventures Life Sciences CEO Forum (Sep 2003).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. 2003 Dorsey Hughes Symposium (Jul 2003).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. MPM Capital Annual Healthcare Conference (Jun 2003).
  • Poste, George. Policy Formulation in Addressing the Global Challenge of Biosecurity. Joint Symposium: International Institute for Strategic Studies, Chemical and Biological Arms Control Institute and Institute of Medicine, Forum on Emerging Infections (Jun 2003).
  • Poste, George. The Productivity and Paradox in Pharmaceutical R&D. The Biopharmaceutical Conference in Europe (Jun 2003).
  • Poste, George. The Path Towards Personalized Medicine. Amersham Lecture (Apr 2003).
  • Poste, George. Genes and Molecular Medicine. The Golden Double Helix: 50 Years of DNA Conference (Apr 2003).
  • Poste, George. Optimizing R&D Strategies and Productivity in the Pharmaceutical and Biotechnology Indsutries: Adaptive Incremental Change? Or Radical Revision?. R&D Leaders Forum (Apr 2003).
  • Poste, George. Strategic Challenges for the Industry: Molecular Medicine, Political Activism and the Rise of Bioterrorism. (Mar 2003).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. (Mar 2003).
  • Poste, George. International Philanthropy and Meeting the Challenge of Combating Global Disease. Hever 8 (Mar 2003).
  • Poste, George. Molecular Medicine and the Evolution of Healthcare Delivery. AdvancePCS Client Conference (Mar 2003).
  • Poste, George. New National Security Challenges Posed by Advances in Biotechnology. NRO (Mar 2003).
  • Poste, George. The Life Sciences: A Crucial New Element in the Calculus of National Security and Foreign Affairs. (Mar 2003).
  • Poste, George. The Increasing Importance of the Life Sciences in National Security and Foreign Affairs. (Jan 2003).
  • Poste, George. The Technological Drivers of Molecular Medicine. Financial Times Biotechnology Conference (Nov 2002).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. Keynote address, S.G. Cowan Annual Healthcare Conference (Nov 2002).
  • Poste, George. The Impact of New Genetic Technologies on Clinical Medicine. Financial Times Global Biotechnology Conference (Nov 2002).
  • Poste, George. The Promise and Peril of the Biotechnology Revolution. World Medical Association 54th General Assembly (Oct 2002).
  • Poste, George. Systems Biology: Where Are We, Where Are We Going?. The Biotech Meeting at Laguna Niguel (Oct 2002).
  • Poste, George. The Critical Role of Diagnostic Tests in Bioterrorism Defense. Washington G-2 Reports Lab Institute Annual Symposium (Oct 2002).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. Keynote Address, Atlas Ventures Annual Life Sciences Conference (Oct 2002).
  • Poste, George. Science and Technology in an Era of Terrorism. Chemical and Biological Arms Control Institute (Oct 2002).
  • Poste, George. Systems Biology: Understanding the Design Principles of Complex Biological Networks. Keynote Address, Novo Biosummit (Sep 2002).
  • Poste, George. Science in the Service of the Nation: Strategic Concepts in Biodefense. Defense Science Board Symposium (Aug 2002).
  • Poste, George. The National Security Implications of Advances in Genomics, Robotics, Artificial Intelligence and Nanotechnology (GRAIN). NATO Conference (Jul 2002).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. Keynote address, 6th International Biotech and Infotech Summit (Jun 2002).
  • Poste, George. Bioterrorism, Biotechnology and Biosecurity. Jean Shanks Lecture (May 2002).
  • Poste, George. Leveraging Internet Based Relationships to Improve R&D Strategies. Keynote Address. ePharma Summit (May 2002).
  • Poste, George. New World Order: Threat or Opportunity for the Pharmaceutical Industry. World Pharmaceutical Industry R&D Directors Meeting (Hever 7) (May 2002).
  • Poste, George. Biotechnology, Bioterrorism and Biosecurity. (May 2002).
  • Poste, George. The Rise of Molecular Medicine. Keynote Address. Advance PCS Annual Healthcare Meeting (Apr 2002).
  • Poste, George. The Elucidation of Regulatory Networks in Complex Biological Systems: The Convergence of Biology. Medicine and Computing (Mar 2002).
  • Poste, George. Molecular Diagnostics: A Powerful New Value Driver in Healthcare and Bioterrorism Defense. Bank of America Diagnostics Conference (Mar 2002).
  • Poste, George. Biotechnology and the Emergence of Molecular Medicine. Advance PCS 2002 Client Conference (Mar 2002).
  • Poste, George. Sensors and Sensing: Technical Realities Versus Political Desires. SAIC:DARPA Meeting (Feb 2002).
  • Poste, George. Bioterrorism, Biotechnology and Biosecurity. J.P. Morgan / Hamrecht and Quist Annual Biotechnology Conference (Jan 2002).
  • Poste, George. Biotechnology and the Bioterrorism Dilemma. (Jan 2002).
  • Poste, George. The Challenge of Bioterrorism. Merrill Lynch 2001 Biotechnology Retreat (Nov 2001).
  • Poste, George. The Collision of Business Necessities and Political Realities. 12th Annual Financial Times World Pharmaceutical Conference (Nov 2001).
  • Poste, George. Genomics, Proteomics and Systems Biology: Managing Platform and Information Overload. 12th Annual Financial Times World Pharmaceutical Conference (Nov 2001).
  • Poste, George. Bioterrorism: Implications for the Biotechnology Industry. 14th Annual Biotechnology CEO Conference (Oct 2001).
  • Poste, George. The Challenge of Bioterrorism. Management Executive Society Meeting (Oct 2001).
  • Poste, George. On Vision: Directions and Dimensions in Life Sciences Research. Atlas Ventures 9th Annual Life Sciences Conference (Sep 2001).
  • Poste, George. The Informational Implications of Genomics, Molecular Medicine and Internet-Based Healthcare Delivery. BIO 2001 (Jun 2001).
  • Poste, George. Future Threats: How Might Philanthropists Best Address Global Infectious Disease?. (May 2001).
  • Poste, George. Genomics, Molecular Medicine and e.Health. Keynote Address Bank of America Securities Healthcare Conference (Mar 2001).
  • Poste, George. Life at the Leading Edge: The Harsh Cusp of Darwinian Selection. Life Science Ventures Conference (Mar 2001).
  • Poste, George. The Internet and the Future Evolution of Healthcare Delivery. Innovation 2001 (Mar 2001).
  • Poste, George. Pharmacogenomics, Molecular Medicine, and the Evolution of Healthcare. ASU College of Pharmacy Conference (Jan 2001).
  • Poste, George. Advances in Biotechnology: Promise and Peril. Second National Symposium on Bioterrorism (Nov 2000).
  • Poste, George. Genetics and Computing: The Drivers of Systems Biology, Molecular Medicine and e.Health. Scientific American BioSilico 2000 (Oct 2000).
  • Poste, George. Genetics and Computing: The Forces Shaping the Evolution of Systems Biology and Molecular Medicine. Nuffield Department of Clinical Medicine, University of Oxford, Retirement Symposium for Sir David Weatherall (Sep 2000).
  • Poste, George. Genetics, Informatics and the Evolution of Molecular Medicine. Plenary Lecture, Biotechnology 2000 (Sep 2000).
  • Poste, George. Regulatory and Legislative Considerations in the Therapeutic Applications of Cloning and Stem Cells. Royal Society of Edinburgh Conference on Cloning, Stem Cells and Stem Therapy (Sep 2000).
  • Poste, George. The Pharmaceutical Industry and the Evolution of Molecular Medicine. Awards Ceremony Lecture at British Pharmaceutical Conference (Sep 2000).
  • Poste, George. Molecular Medicine, Population Genetics and the Future of Healthcare Delivery. Datta Lecture, 18th International Congress of Biochemistry and Molecular Biology (Jul 2000).
  • Poste, George. Predictions for the Use of Genomics. AACP Annual Meeting (Jul 2000).
  • Poste, George. The Biotechnology Sector: Aspirations, Alliances and Adaptability. 11th Annual Financial Times Pharmaceuticals Conference (Jun 2000).
  • Poste, George. The Future of Public Health. Keynote Address, US Public Health Service Annual Conference (Jun 2000).
  • Poste, George. Genomics and Internet-Based Healthcare : The Key Drivers of Radical Change in Medicine and Healthcare. Nasdaq 2000 Conference: Into the 21st Century -Genomics and Beyond (Jun 2000).
  • Poste, George. Genomics, Molecular Medicine and e.Health. Keynote address, Life Sciences e.Health Partnering and Investment Meeting (Jun 2000).
  • Poste, George. Genomics and Informatics : The Key Technology Drivers for the Evolution of Molecular Medicine. Keynote Address, Pharmaceutical Research and Manufacturers of America Annual Scientific Symposium (May 2000).
  • Poste, George. Promoting Innovative R&D in Infectious Diseases: Research, Regulations, Reward and Responsibility. The Royal Society Antimicrobial Resistance Conference (May 2000).
  • Poste, George. New Dual Use Technologies and Bioterrorism. Keynote Address, National Military Intelligence Association Annual Symposium (May 2000).
  • Poste, George. The Key Drivers of Radical Change in Healthcare. USP Quinquennial Meeting Symposium (Apr 2000).
  • Poste, George. The Convergence of Genetics and Computing: The Key Drivers of Business Opportunities in Healthcare. Wharton Business School's New Ventures in Healthcare Conference (Apr 2000).
  • Poste, George. Regenerative Medicine. HealthCare Ventures LLC 2000, Scientific Advisory Board Millennium Retreat (Mar 2000).
  • Poste, George. Healthcare - What Next?. The National Council of Women's Millennium Seminar (Mar 2000).
  • Poste, George. Molecular Medicine and the Future Healthcare Delivery. Eighth Glaxo Wellcome Lecture (Mar 2000).
  • Poste, George. Pharmacogenomics and the Evolution of Rational Healthcare. The 2nd Annual Pharmacogenomics Event (Jan 2000).
  • Poste, George. What is Biotechnology. Foreign Commercial Service of the Embassy of the USA (Jan 2000).
Service
  • Sloan Foundation Expert Advisory Group on Influenza Pandemic Preparedness, Member (2009 - Present)
  • Synthetic Genomics, Scientific Advisory Board (2009 - Present)
  • Editorial Board, Bioterrorism and Biosecurity, Member (2008 - Present)
  • Caris Life Sciences, Vice Chairman (2005 - Present)
  • Burrill and Company, Advisory Board (2004 - Present)
  • Exelixis, Board Member (2004 - Present)
  • Exelixis, Board Member (2004 - Present)
  • Monsanto, Board Member (2003 - Present)
  • The Institute of Medicine of The National Academies, Forum on Microbial Threats, Member (2003 - Present)
  • Orchid Biosciences, Chairman (2002 - Present)
  • Defense Health Board, US Department of Defense, Member (2008 - 2009)
  • Defense Science Board, US Department of Defense, Member (2003 - 2009)
  • Orchid Biosciences, Chairman (2002 - 2009)
  • Sloan Foundation Task Force on Synthetic Biology, Member (2008 - 2008)
  • The Institute of Medicine of The National Academies, Committee Member (2006 - 2006)
  • Institute of Medicine of The National Academies, Committee Member (2005 - 2006)
  • Institute of Medicine: National Research Council, US National Academy of Sciences, Member (2005 - 2006)
  • The Institute of Medicine of The National Academies, Committee Member (2005 - 2005)
  • Threat Reduction Advisory Committee, United States Department of Defense, Member (2001 - 2005)
  • AdvancePCS, Board Member (2002 - 2003)
  • Board of Trustees; The International Vaccine Institute, Seoul, Korea, Member (2000 - 2003)
  • Illumina, Board Member (2000 - 2003)
  • Maxygen, Board Member (2000 - 2003)
  • Structural GenomiX, Chairman (2000 - 2003)
  • diaDexus, Chairman (1997 - 2003)
  • Governing Board, Beckman Center for Molecular and Genetic Medicine, Stanford University, Member (1993 - 2003)
  • Financial Times Annual Biotechnology Conference London, Chair (2003 - 2003)
  • Rand Critical Technologies Task Force on The Hybrid Carbon Silicon Brain, Committee Member (1998 - 2001)
  • Rand Critical Technologies Task Force on The Hybrid Carbon Silicon Brain, Member (1998 - 2001)
  • BP Technology Advisory Council, Member (1998 - 2000)
  • Board of Medical Governors, World Economic Forum, Davos, Member (1998 - 2000)
  • Advisory Committee on International Economic Policy, United States State Department, Member (Present)
  • Biological Weapons Working Group, National Academy of Sciences, Member (Present)
  • Board of Trustees; The International Vaccine Institute, Seoul, Korea, Member (Present)
  • Board on Global Health, National Academy of Sciences Institute of Medicine, Member (Present)
  • Committee on Advances in Technology and Next Generation Biowarfare Threats. Institute of Medicine: National Research Council, US National Academy of Sciences, Member (Present)
  • Defense Science Board, United States Department of Defense, member (Present)
  • Editorial Board, Bioterrorism and Biosecurity, Member (Present)
  • Editorial Board, Current Opinion in Biotechnology, Member (Present)
  • Editorial Board, Expert Opinion on Investigational Drugs, Member (Present)
  • Editorial Board, Expert Opinion on Molecular Diagnostics, Member (Present)
  • Editorial Board, Journal of Commercial Biotechnology, Member (Present)
  • Editorial Board, Nature Bio/Technology, Member (Present)
  • Editorial Board, Pharmacogenomics, Member (Present)
  • Editorial Board, Polymers in Medicine and Biotechnology, Member (Present)
  • Editorial Board, The Journal of Biolaw and Business, Member (Present)
  • Senior Advisory Panel, Current Drugs, Member (Present)