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Neal Woodbury

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ASU Knowledge Enterprise
Vice President of Research, Chief Science + Technology Officer & Professor
Administrative, TEMPE Campus, Mailcode 7205
School of Molecular Sciences
Interim Executive Vice President + Technology Officer
Faculty w/Admin Appointment, TEMPE Campus, Mailcode 7205
Lincoln Center Applied Ethics
Lincoln Center Affiliated Faculty
Faculty, TEMPE Campus, Mailcode 7205
Biography: 

Neal Woodbury is vice president for research and chief science and technology officer for ASU’s Knowledge Enterprise. In this capacity, he advances ASU’s high-level research initiatives and activities. 

Throughout the course of his 33-year tenure with ASU, Woodbury has been a trusted resource and advocate for ASU’s research enterprise, regularly advising ASU leadership on issues related to the university’s major research activities. He has been responsible for developing new, large-scale, collaborative projects, as well as facilitating broad interactions between the Knowledge Enterprise and ASU’s academic units.

Woodbury is concurrently a senior global futures scientist with the Julie Ann Wrigley Global Futures Laboratory and a faculty member in the Biodesign Center for Innovations in Medicine, the School of Molecular Sciences and the Global Security Initiative. He previously served as deputy director of the Biodesign Institute and has a well earned reputation as an astute and engaged leader. Woodbury is also past CEO of Science Foundation Arizona, a role in which he helped advance the goals of SFAz as a force for promoting science, high-tech industry and STEM education across Arizona. 

An esteemed researcher, Woodbury has published more than 165 scientific works. He is an expert in electron transfer and photosynthesis, and he has expanded his vast research repertoire as a human disease detective, co-founding HealthTell with ASU Professor Stephen Johnston. HealthTell focused on a diagnostic technology known as immunosignaturing, which involves fabrication of large numbers of peptides or related heteropolymers on silicon wafers. The resulting peptide arrays are the basis of a diagnostic platform that generates a comprehensive profile of circulating antibodies. 

In addition to his academic and research achievements, Woodbury is a fellow of the National Academy of Inventors and holds seven patents. He completed his PhD in biochemistry at the University of Washington and holds a bachelor’s degree in biochemistry from the University of California at Davis.

CV
Binary Data Curriculum Vitae
Education: 
  • Ph.D. Biochemistry, University of Washington 1986
  • B.S. Biochemistry, University of California-Davis 1979

 

Research Website URL: 
https://biodesign.asu.edu/neal-woodbury
Research Interests: 

Chemical Diversity: A major competency of BON is in the creation, generation and searching of chemical space. We have multiple methods for accomplishing this. We are currently using the technique of mRNA display to search libraries of peptides and proteins as large as 1013-14 and select those with the desired traits. We have also developed the capability to synthetically create libraries on the order of 106 peptides or other synthetic chemical structures using the kind of light directed synthesis that is used in the generation of DNA chips. We have generalized the chemistry to be used for other kinds of compounds that can be constructed from building block components.

Synthetic Antibodies (Synbodies): We are collaborating with the Biodesign Institute's Center for Innovations in Medicine to apply our chemical diversity capability to the production of synthetic antibodies. Here, we use various methods to search chemical space for weak binders and then orient them to create systems with high affinity and specificity, mimicking antibody function.

Creation Generation of Catalysts for Energy Conversion using Patterned Synthesis: We have utilized our directed synthetic chemical diversity platform (described above) to create tens of thousands of potential electro-catalysts directly on electrodes. We are synthesizing libraries of metal binding peptides to search for new water splitting catalysts that mimic the activity of the oxygen evolving complex of photosystem II in collaboration with ASU professors James Allen and JoAnn Williams of the chemistry and biochemistry department and Trevor Thornton of the electrical engineering department.

Optically Directed Cellular Evolution: We are also extending our optical patterning of chemistry to cells. We have developed a means of patterning cell growth on a surface using the photolyase repair system to affect light activated rescue from cell death. This makes it possible to observe a large number of cells on a surface and then select a subset to allow to grow while killing the remainder.

Ultrafast Laser Spectroscopy and Microscopy: BON members manage ASU�"s ultrafast laser spectroscopy and microscopy facility, and this represents another of our key competencies. The facility is well equipped with state-of-arts ultrafast lasers and detection systems, including 2 transient absorption spectrometers, a kilohertz femtosecond up-conversion apparatus, a single photon counting system, a streak camera fluorescence FLIM spectrometer, 2 microscope systems for single molecule spectroscopy. Here it is possible to perform femtosecond timescale spectroscopy in many different forms (absorbance, fluorescence, etc.) both in solution, on surfaces, in living cells or tissues and at the single molecule level.

The Role of Protein Dynamics in Photosynthetic Electron Transfer: We have a fundamental program in the study of the ultrafast electron transfer reactions of bacterial photosynthetic reaction centers. This work utilizes ASU�"s ultrafast laser facility to follow these electron transfer reactions on the femtosecond to picosecond timescale. Recently, we have discovered that the kinetics of electron transfer in this system is directly limited by protein motion and we are continuing to explore how this complex protein dance serves to mediate biochemical reaction.

Analyzing the Structure and Dynamics of Chromatin: The critical role of chromatin structure in controlling gene expression is becoming more and more evident. Of particular interest to us is the dynamics of the DNA/protein interaction in the nucleosome, the most elemental chromatin structural component. We are using single molecule spectroscopy and AFM to explore the structure and dynamics of these particles as a function of DNA sequence and under the influence of transcription factors that affect gene expression. This work is done in collaboration with the Biodesign Institute's Center for Single Molecule Biophysics (Stuart Lindsay and with Dennis Lohr in ASU's chemistry and biochemistry department).

Publications: 
  • Taguchi, A.T., Boyd, J., Diehnelt, C.W., Legutki, J.B., Zhao, Z-G, Woodbury, N.W., Comprehensive Prediction of Molecular Recognition in a Combinatorial Chemical Space Using Machine Learning.  ACS Combinational Science (2020).
  • Singh, A., Mandal, S., Carey, A-M, Liu, M., Chen, S., Seo, D-K, Yan, H., Woodbury, Neal.  Interfacing Photosystem I Reaction Centers with a Porous Antimony-Doped Tin Oxide Electrode to Perform Light Driven Redox Chemistry.  Biophysical Journal (2019).
  • Mandal, S., Zhou, X., Lin, S., Yan, H., Woodbury, Neal.  Directed Energy Transfer through DNA-Templated J-Aggregates.  Bioconjugate Chemistry (2019).
  • Zhou, X., Mandal, S., Jiang, S., Lin, S., Yang, J., Liu, Y., Whitten, D.G., Woodbury, N.W., Yan, H.  Efficient Long-Range, Directional Energy Transfer through DNA-Templated Dye Aggregates. Journal of American Chemical Society (2019). 
  • Boulais, E. Sawaya, N. P. D. Veneziano, R. Andreoni, A. Banal, J. L. Kondo, T. Mandal, S. Lin, S. Schlau-Cohen, G. S. Woodbury, N. W. Yan, H. Aspuru-Guzik, A. Bathe, M. Programmed coherent coupling in a synthetic DNA-based excitonic circuit. Nature Materials (2018).
  • Mandal, S., Espiritu, E., Akram, N., Lin, S., Williams, J.C.,  Allen, J.P., Woodbury, N.W.  Influence of the Electrochemical Properties of the Bacteriochlorophyll Dimer on Triplet Energy-Transfer Dynamics in Bacterial Reaction Centers.  Journal of Physical Chemistry B (2018).
  • Mieritz, D., Liang, R., Zhang, H., Carey, A-M, Chen, S., Volosin, A., Lin, S., Woodbury, N., Seo, D-K.  Thickness-Dependent Bioelectrochemical and Energy Applications of Thickness-Controlled Meso-Macroporous Antimony-Doped Tin Oxide.  Coatings (2018).
  • Mandal, S., Zhou, X., Fahmi, N.E., Lin, S., Yan, H., Woodbury, N.  Quantum Dot-based Fluorescence Resonance Energy Transfer through Exciton Dynamics in SDNA-Templated J-Aggregates.  Biophysical Journal (2018).
  • Boulais, E., Sawaya, N.P.D., Veneziano, R., Andreoni,  A., Banal, J.L., Kondo, T., Mandal, S., Lin, S., Schlau-Cohen, G.S., Woodbury, N.W., Yan, H., Aspuru-Guzik, A., Bathe, M.  Programmed coherent coupling in a synthetic DNA-based excitonic circuit.  Nature Materials (2018).
  • Zhao, Z. G. Cordovez, L. A. Johnston, S. A., Woodbury, N. Peptide Sequencing Directly on Solid Surfaces Using MALDI Mass Spectrometry. Scientific Reports (2017).
  • Zhang, H. J. Carey, A. M. Jeon, K. W. Liu, M. H. Murrell, T. D. Locsin, J. Lin, S. Yan, H. Woodbury, N. Seo, D. K. A highly stable and scalable photosynthetic reaction center-graphene hybrid electrode system for biomimetic solar energy transduction. Journal of Materials Chemistry A (2017).
  • Mandal, S. Carey, A. M. Locsin, J. Gao, B. R. Williams, J. C. Allen, J. P. Lin, S. Woodbury, N. W. Mechanism of Triplet Energy Transfer in Photosynthetic Bacterial Reaction Centers. J Phys Chem B (2017).
  • Carey, A. M. Zhang, H. Liu, M. Sharaf, D. Akram, N. Yan, H. Lin, S. Woodbury, N. W. Seo, D. K. Enhancing Photocurrent Generation in Photosynthetic Reaction Center-Based Photoelectrochemical Cells with Biomimetic DNA Antenna. ChemSusChem (2017).
  • Andreoni, A. Lin, S. Liu, H. Blankenship, R. E. Yan, H. Woodbury, N. W. Orange Carotenoid Protein as a Control Element in an Antenna System Based on a DNA Nanostructure. Nano Lett (2017).
  • Zhao, Z. Fu, J. L. Dhakal, S. Johnson-Buck, A. Liu, M. H. Zhang, T. Woodbury, N. W. Liu, Y. Walter, N. G. Yan, H. Nanocaged enzymes with enhanced catalytic activity and increased stability against protease digestion. Nature Communications (2016).
  • Sun, C. Carey, A. M. Gao, B. R. Wraight, C. A. Woodbury, N. W. Lin, S. Ultrafast Electron Transfer Kinetics in the LM Dimer of Bacterial Photosynthetic Reaction Center from Rhodobacter sphaeroides. Journal of Physical Chemistry B (2016).
  • Pan, J. Saer, R. Lin, S. Beatty, J. T. Woodbury, N. W. Electron Transfer in Bacterial Reaction Centers with the Photoactive Bacteriopheophytin Replaced by a Bacteriochlorophyll through Coordinating Ligand Substitution. Biochemistry (2016).
  • Liu, M. H. Fu, J. L. Qi, X. D. Wootten, S. Woodbury, N. W. Liu, Y. Yan, H. A Three-Enzyme Pathway with an Optimised Geometric Arrangement to Facilitate Substrate Transfer. Chembiochem (2016   ).
  • Carey, A. M. Zhang, H. Mieritz, D. Volosin, A. Gardiner, A. T. Cogdell, R. J. Yan, H. Seo, D. K. Lin, S. Woodbury, N. W. Photocurrent Generation by Photosynthetic Purple Bacterial Reaction Centers Interfaced with a Porous Antimony-Doped Tin Oxide (ATO) Electrode. ACS Appl Mater Interfaces (2016).
  • Boulais, E. Sawaya, N. Veneziano, R. Andreoni, A. Lin, S. Woodbury, N. Yan, H. Aspuru-Guzik, A. Bathe, M. A DNA-Based Building Block for Designer Excitonic Circuits. Biophysical Journal (2016).
  • Andreoni, A. Lin, S. Liu, H. J. Yan, H. Blankenship, R. E. Woodbury, N. W. Light-Activated Photo Protection in an Artificial Antenna System. Biophysical Journal (2016).
  • Wang, Wei; Woodbury, Neal W. Unstructured interactions between peptides and proteins: Exploring the role of sequence motifs in affinity and specificity. Acta Biomaterialia (2015).
  • Driscoll, B.; Lunceford, C.; Lin, S.; Woronowicz, K.; Niederman, R. A.; Woodbury, N. W. Energy transfer properties of Rhodobacter sphaeroides chromatophores. PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2014).
  • Dutta, Palash; Levenberg, Symon; Loskutov, Andrey; Jun, Daniel; Saer, Rafael; Beatty, J.; Lin, Su; Liu, Yan; Woodbury, Neal; Yan, Hao. A DNA-Directed Light-Harvesting/Reaction Center System. : Journal of the American Chemical Society (2014).
  • Dutta, Palash; Lin, Su; Loskutov, Andrey; Levenberg, Symon; Jun, Daniel; Saer, Rafael; Beatty, John; Liu, Yan; Yan, Hao; Woodbury, Neal. Reengineering the Optical Absorption Cross-section of Photosynthetic Reaction Centers. Journal of the American Chemical Society (2014).
  • Fu, Jinglin; Yang, Yuhe Renee; Johnson-Buck, Alexander; Liu, Minghui; Liu, Yan; Walter, Nils G.; Woodbury, Neal W.; Yan, Hao. Multi-enzyme complexes on DNA scaffolds capable of substrate channelling with an artificial swinging arm. NATURE NANOTECHNOLOGY (2014).
  • Legutki, Joseph Barten;Zhao, Zhan-Gong;Greving, Matt;Woodbury, Neal; Johnston, Stephen Albert; Stafford, Phillip. Scalable high-density peptide arrays for comprehensive health monitoring. NATURE COMMUNICATIONS (2014).
  • Navalkar, Krupa Arun; Johnston, Stephen Albert; Woodbury, Neal; Galgiani, John N.; Magee, D. Mitchell; Chicacz, Zbigniew; Stafford, Phillip. Application of Immunosignatures for Diagnosis of Valley Fever. CLINICAL AND VACCINE IMMUNOLOGY (2014).
  • Stafford, Phillip; Cichacz, Zbigniew; Woodbury, Neal W.; Johnston, Stephen Albert. Immunosignature system for diagnosis of cancer. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014).
  • Wang W. Woodbury NW. Selective protein–peptide interactions at surfaces. Acta Biomater (2014).
  • Guo, Zhi; Lin, Su; Woodbury, Neal W. Utilizing the Dynamic Stark Shift as a Probe for Dielectric Relaxation in Photosynthetic Reaction Centers During Charge Separation. JOURNAL OF PHYSICAL CHEMISTRY (2013).
  • LeBard DN, Martin DR, Lin S, Woodbury NW, Matyushov DV. Protein dynamics to optimize and control bacterial photosynthesis. Chemical Science (2013).
  • Liu MH, Fu JL, Heejesen C, Yang YH, Woodbury NW, Gothelf K, Liu Y, Yan H. A DNA tweezer-actuated enzyme nanoreactor. Nature Communications (2013).
  • Pan J, Saer RG, Lin S, Guo Z, Beatty JT, Woodbury NW. The Protein Environment of the Bacteriopheophytin Anion Modulates Charge Separation and Charge Recombination in Bacterial Reaction Centers. Journal of Physical Chemistry B (2013).
  • Saer, Rafael G.; Pan, Jie; Hardjasa, Amelia; Lin, Su; Rosell, Federico; Mauk, A. Grant; Woodbury, Neal W.; Murphy, Michael E. P.; Beatty, J. Thomas. Structural and kinetic properties of Rhodobacter sphaeroides photosynthetic reaction centers containing exclusively Zn-coordinated bacteriochlorophyll as bacteriochlorin cofactors. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2013).
  • H Wang, Y Hao, J Ying, S Lin, NW Woodbury. Role of Protein Dynamics in Guiding Electron-Transfer Pathways in Reaction Centers from Rhodobacter sphaeroides. Journal of Physical Chemistry B (2012).
  • H Wang, Y Jiang, Y Hao, S Lin, NW Woodbury. Role of Protein Dynamics in Guilding Electron-Transfer Pathways in Reaction Centers from Rhodobacter sphaeroides. J. Phys. Chem. B (2012).
  • J Fu, M Liu, Y Liu, NW Woodbury and H Yan. Interenzyme Substrate Diffusion for an Enzyme Cascade Organized on Spatially Addressable DNA Nanostructures. J. Am. Chem. Soc (2012).
  • J Pan, S Lin, NW Woodbury. Bacteriochlorophyll Excited-State Quenching Pathways in Bacterial Reaction Centers with the Primary Donor Oxidized. J Phys Chem B (2012).
  • Z Guo, S Lin, J Pan, N Woodbury. Protein Dielectric Environment Modulates the Electron Transfer Pathway in Photosynthetic Reaction Centers. Biophysical Journal (2012).
  • J Pan, S Lin, JP Allen, JC Williams, HA Frank, NW Woodbury. Carotenoid Excited-State Properties in Photosynthetic Purple Bacterial Reaction Centers: Effects of the Protein Environment. JOURNAL OF PHYSICAL CHEMISTRY B (2011).
  • JL Fu, J Reinhold, NW Woodbury. Peptide-Modified Surfaces for Enzyme Immobilization. PLOS ONE (2011).
  • Z Guo, S Lin, YY Xin, HY Wang, RE Blankenship, NW Woodbury. Comparing the Temperature Dependence of Photosynthetic Electron Transfer in Chloroflexus aurantiacus and Rhodobactor sphaeroides Reaction Centers. JOURNAL OF PHYSICAL CHEMISTRY B (2011).
  • Greving MP, Kumar P, Zhao ZG, Woodbury NW. Feature-level MALDI-MS characterization of in situ-synthesized peptide microarrays. Langmuir 2010 (2010).
  • J Fu, K Cai, SA Johnston, NW Woodbury. Exploring peptide space for enzyme modulators. J Am Chem Soc (2010).
  • MP Greving, P Kumar, ZG Zhao, NW Woodbury. Feature-level MALDI-MS characterization of in situ-synthesized peptide microarrays. Langmuir (2010).
  • MP Greving, PE Belcher, CD Cox, D Daniel, CW Diehnelt and NW Woodbury. High-throughput screening in two dimensions: binding intensity and off-rate on a peptide microarray. Biochemistry (2010).
  • MP Greving, PE Belcher, CW Diehnelt, MJ Gonzalez-Moa, J Emery, J Fu, SA Johnston, NW Woodbury. Thermodynamic additivity of sequence variations: an algorithm for creating high affinity peptides without large libraries or structural information. PLoS One (2010).
  • Allen JP, Cordova JM, Jolley CC, Murray TA, Schneider JW, Woodbury NW, Williams JC, Niklas J, Klihm G, Reus M, Lubitz W. EPR, ENDOR, and special TRIPLE measurements of P(*+) in wild type and modified reaction centers from Rb. sphaeroides. Photosynth Res (2009).
  • L Kelbauskas, J Yodh, NW Woodbury, D Lohr. Intrinsic promoter nucleosome stability/dynamics variations support a novel targeting mechanism. Biochemistry (2009).
  • Lin S, Jaschke PR, Wang H, Paddock M, Tufts A, Allen JP, Rosell FI, Mauk AG, Woodbury NW, Beatty JT. Electron transfer in the Rhodobacter sphaeroides reaction center assembled with zinc bacteriochlorophyll. Proc Natl Acad Sci U S A (2009).
  • Williams BA, Diehnelt CW, Belcher P, Greving M, Woodbury NW, Johnston SA, Chaput JC. Creating protein affinity reagents by combining peptide ligands on synthetic DNA scaffolds. J Am Chem Soc (2009).
  • Chaput JC, Woodbury NW, Stearns LA, Williams BA. Creating protein biocatalysts as tools for future industrial applications. Expert Opin Biol Ther (2008).
  • L Kelbauskas, J Sun, NW Woodbury, D Lohr. Nucleosomal stability and dynamics vary significantly when viewed by internal versus terminal labels. Biochemistry (2008).
  • T Northen, MP Greving, N Woodbury. Combinatorial screening of biomimetic protein affinity materials. Advance Materials (2008).
  • Gibasiewicz K, Ramesh VM, Lin S, Redding K, Woodbury NW, Webber AN. Two equilibration pools of chlorophylls in the Photosystem I core antenna of Chlamydomonas reinhardtii. Photosynth Res (2007).
  • Katilius E, Flores C, Woodbury NW. Exploring the Sequence Space of a DNA Aptamer Using Microarrays. Nucleic Acids Research (2007).
  • Katilius E, Flores C, Woodbury NW. Exploring the sequence space of a DNA aptamer using microarrays. Nucleic Acids Res (2007).
  • L Kelbauskas, N Chan, R Bash, J Yodh, N Woodbury, and D.Lohr. Sequence-dependent nucleosome structure and stability variations detected by Fo¨rster Resonance Energy Transfer. Biochemistry (2007).
  • L Kelbauskas, N Chan, R Bash, P DeBartolo, J Sun, N Woodbury, and D Lohr. Sequence-dependent variations associated with H2A/H2B depletion of nucleosomes. Biophys J (2007).
  • Wang H, Lin S, Allen JP, Williams JC, Blankert S, Laser C, Woodbury NW. Protein dynamics control the kinetics of initial electron transfer in photosynthesis. Science (2007).
  • E katilius, Neal Woodbury. Multi-photon Excitation of Flourescent DNA Base Analogs. J.Biomed.Opt (2006).
  • E Katilius, Neal Woodbury. Multi-photon exitation of fluorescent DNA base analogs. J.Biomed.Opt (2006).
  • E katilius, Z Katiliene, Neal Woodbury. Signaling Aptamers Created Using Fluorescent Nucleotide Analogs. Analytical Chemistry (2006).
  • E Katilius, Z Katiliene, Neal Woodbury. Singlaling aptamers created using fluorescent nucleotide analogs. Analytical Chemistry (2006).
  • H Wang, S Lin, Neal Woodbury. Electronic Transitions od the Soret Band of Reaction Centers from Rhodobacter Sphaeroides Studied by Femtosecond Transient Absorbance Spectroscopy. J.Phys.Chem B (2006).
  • H Wang, S Lin, Neal Woodbury. Electronic Transitions of the Soret Band of Reaction Centers from Rhodobacter sphaeroides Studied by Femtosecond Transient Absorbance Spectroscopy. J. Phys. Chem B (2006).
  • S Lin, E Katilius, R IIagan, G Gibson, H Frank, Neal Woodbury. Mechanism of Cartenoid Singlet Excited State Energy Transfer in Modified Bacterial Reation Centers. J.Phys.Chem.B (2006).
  • S Lin, E Katilius, R Ilagan, G Gibson, H Frank, Neal Woodbury. Mechanism of carotenoid singlet excited state energy transfer in modified bacterial reaction centers. J. Phys. Chem. B (2006).
  • T Northen, D Brune, Neal Woodbury. Synthesis and Characterization of Peptide Grafted Porous Polymer Microstructures. Biomacromolecules (2006).
  • A Haffa, S Lin, R LoBrutto, J Williams, A Taguchi, J Allen, Neal Woodbury. Environmental Control of Primary Photochemistry in a Mutant Bacterial Reaction Center. Journal of Physical Chemistry B (2005).
  • A Scruggs, C Flores, Rebekka Wachter, Neal Woodbury. Development and Characterization of Green Fluorescent Protein Mutants with Altered Lifetimes. Biochemistry (2005).
  • D LoVullo, D Daniel, J Yodh, Dennis Lohr, Neal Woodbury. A Fluorescence resonance energy transfer-based probe to monitor nucleosome structure. Analytical Biochemistry (2005).
  • T Northen, Neal Woodbury. Light-Directed Movement of Polymer Microstructures. Langmuir (2005).
  • Katilius, E, Woodbury, Neal Walter. Purple bacteria: Electron Acceptors and Donors. Encyclopedia of Biological Chemistry (2004).
  • A Haffa, Su Lin, J Williams, B Bowen, A Taguchi, J Allen, Neal Woodbury. Controlling the Pathway of Photosynthetic Charge Separation in Bacterial Reaction Centers. J. Phys. Chem. B (2004).
  • B Bowen, A Scruggs, J Enderlein, M Sauer, Neal Woodbury. Implementation of neural networks for the identification of single-molecules. J. Phys. Chem. A (2004).
  • E Katilius, J Babendure, S Lin, Neal Woodbury. Electron Transfer Dynamics in Rhodobacter sphaeroides Reaction Center Mutants with a Modified Ligand for the Monomer Bacteriochlorophyll on the Active Side. Photosynth. Res (2004).
  • E Katilius, Neal Woodbury. Multi-Photon Excitation Fluorescence Correlation Spectroscopy of Fluorescent DNA Base Analogs. Proc. of SPIE (2004).
  • R Sension, A Cole, A Harris, C Fox, Neal Woodbury, S Lin, E Marsh. Photolysis and Recombination of Adenosylcobalamin Bound to Glutamate Mutase. J. Phys. Chem. B (2004).
  • Z Katiliene, G Uyeda, Evaldas Katilius, J Williams, Neal Woodbury. Increasing the rate of energy transfer between the LHI antenna and the reaction center in the photosynthetic bacterium Rhodobacter sphaeroides. J. Phys. Chem. B (2004).
  • . . Encyclopedia of Biological Chemistry (2004).
  • A Freiberg, M Ratsep, K Timpmann, G Trinkunas, Neal Woodbury. Self-trapped excitons in LH2 antenna complexes between 5 K and ambient temperature. Journal of Physical Chemistry B (2003).
  • A Haffa, S Lin, J Williams, A Taguchi, J Allen, Neal Woodbury. High yield of long-lived B-side charge separation at room temperature in mutant bacterial reaction centers. Journal of Physical Chemistry B (2003).
  • A Scruggs, Neal Woodbury. Optical Processing of Bacterial Libraries for Directed Evolution. Biotechnology and Bioengineering (2003).
  • B Bowen, J Enderlein, Neal Woodbury. Single-molecule Fluorescence Spectroscopy of TOTO on Poly-AT and Poly-GC DNA. Photochemistry and Photobiology (2003).
  • B Bowen, Neal Woodbury. Single-Molecule Fluorescent Lifetime and Anisotropy Measurements of the Red Fluorescent Protein, DsRed, in Solution. Photochemistry and Photobiology (2003).
  • B Bowen, Neal Woodbury. TOTO Binding Affinity Analysis Using Single-Molecule Fluorescence Spectroscopy. Photochemistry and Photobiology (2003).
  • E Katilius, J Bever, Z Katiliene, S Lin, A Taguchi, Neal Woodbury. Manipulations of the B-Side Charge-Separated States Energetics in the Rhodobacter sphaeroides Reaction Center. Journal of Physical Chemistry (2003).
  • G Montano, B Bowen, J LaBelle, Neal Woodbury, V Pizziconi, R Blankenship. Characterization of Chlorobium tepidum chlorosomes- A calculation of bacteriochlorophyll c per chlorosome and oligomer modeling. Biophysical Journal (2003).
  • J Babendure, Dennis Lohr, Neal Woodbury, P Liddell, R Bash, D LoVullo, T Schiefer, M Williams, D Daniel, M Thompson, A Taguchi. Development of a Fluorescent Probe for the Study of Nucleosome Assembly and Dynamics. Analytical Biochemistry (2003).
  • K Gibasiewicz, V Ramesh, S Lin, K Redding, Neal Woodbury, A Webber. Excitonic interactions in wild-type and mutant PSI reaction centers. Biophys. J (2003).
  • S Lin, E Katilius, A Taguchi, Neal Woodbury. Excitation energy transfer from carotenoid to bacteriochlorophyll in the photosynthetic purple bacterial reaction center of Rhodobacter sphaeroides. Journal of Physical Chemistry (2003).
  • Z Katiliene, E Katilius, Neal Woodbury. Energy Trapping and Detrapping in Reaction Center Mutants from Rhodobacter sphaeroides. Biophysical Journal (2003).
  • Z Katiliene, E Katilius, Neal Woodbury. Single Molecule Detection of DNA Looping by NgoMIV Restriction Endonuclease. Biophysical Journal (2003).
  • A Haffa, S Lin, E Katilius, J Williams, A Taguchi, J Allen, Neal Woodbury. The dependence of the initial electron-transfer rate on driving force in Rhodobacter sphaeroides reaction Centers. J. Phys. Chem. B (2002).
  • D Daniel, M Thompson, Neal Woodbury. DNA-binding interactions and conformational fluctuations of Tc3 transposase DNA binding domain examined with single molecule fluorescence spectroscopy. Biophys. J (2002).
  • E Katilius, Z Katiliene, S Lin, A Taguchi, Neal Woodbury. B side electron transfer in a Rhodobacter sphaeroides reaction center mutant in which the B side monomer bacteriochlorophyll is replaced with bacteriopheophytin: Low-temperature study and energetics of charge-separated states. J. Phys. Chem. B (2002).
  • E Katilius, Z Katiliene, S Lin, A Taguchi, Neal Woodbury. B-side electron transfer in the HE(M182) reaction center mutant from Rhodobacter sphaeroides. J. Phys. Chem. B (2002).
  • J Yodh, Neal Woodbury, L Shlyakhtenko, Y Lyubchenko, Dennis Lohr. Mapping nucleosome locations on the 208-12 by AFM provides clear evidence for cooperativity in array occupation. Biochemistry (2002).
  • K Gibasiewicz, V Ramesh, S Lin, Neal Woodbury, A Webber. Excitation dynamics in eukaryotic pS I from Chlamydomonas reinhardtii CC 2696 at 10 K. Direct detection of the reaction center exciton states. J. Phys. Chem. B (2002).
  • J Williams, A Haffa, J McCulley, Neal Woodbury, James Allen. Electrostatic interactions between charged amino acid residues and the bacteriochlorophyll dimer in reaction centers from Rhodobacter sphaeroides. Biochemistry (2001).
  • K Gibasiewiez, V Ramesh, A Melkozernov, S Lin, Neal Woodbury, R Blankenship, A Webber. Excitation dynamics in the core antenna of PSI from Chlamydomonas reinhardtii CC 2696 at room temperature. J. Phys. Chem. B (2001).
  • K Timpmann, Z Katiliene, Neal Woodbury, A Freiberg. Exciton self trapping in one-dimensional photosynthetic antennas. J. Phys. Chem. B (2001).
  • M Thompson, Neal Woodbury. Thermodynamics of specific and nonspecific DNA binding by two DNA-binding domains conjugated to fluorescent probes. Biophys. J (2001).
  • R Bash, J Yodh, Y Lyubchenko, Neal Woodbury, D Lohr. Population analysis of subsaturated 172-12 nucleosomal arrays by atomic force microscopy detects nonrandom behavior that is favored by histone acetylation and short repeat length. J. Biol. Chem (2001).
  • S Devanathan, S Lin, M Cusanovich, Neal Woodbury, G Tollin. Early photocycle kinetic behavior of the E46A and Y42F mutants of photoactive yellow protein: Femtosecond spectroscopy. Biophys. J (2001).
  • Su Lin, Evaldas Katilius, A Haffa, A Taguchi, Neal Woodbury. Blue light drives B-side electron transfer in bacterial photosynthetic reaction centers. Biochemistry (2001).
  • D Daniel, M Thompson, Neal Woodbury. Fluorescence intensity fluctuations of individual labeled DNA fragments and a DNA binding protein in solution at the single molecule level: A comparison of photobleaching, diffusion, and binding dynamics. J. Phys. Chem. B (2000).
  • J Eastman, A Taguchi, S Lin, J Jackson, Neal Woodbury. Characterization of a Rhodobacter capsulatus reaction center mutant that enhances the distinction between spectral forms of the initial electron donor. Biochemistry (2000).
  • K Timpmann, Neal Woodbury, A Freiberg. Unraveling exciton relaxation and energy transfer in LH2 photosynthetic antennas. J. Phys. Chem. B (2000).
  • S Devanathan, S Lin, M Cusanovich, Neal Woodbury, G Tollin. Early intermediates in the photocycle of the Glu46Gln mutant of photoactive yellow protein: Femtosecond spectroscopy. Biophys. J (2000).
  • D Mieritz, R Liang, H Zhang, A M Carey, S Chen, A Volosin, S Lin, Neal Woodbury, D K Seo.  Thickness-dependent bioelectrochemical and energy applications of thickness-controlled meso-macroporous antimony-doped tin oxide.  Coatings (2018).
  • S Mandal, E Espiritu, N Akram, S Lin, J C Williams, J P Allen, Neal Woodbury.  Influence of the Electrochemical Properties of the Bacteriochlorophyll Dimer on Triplet Energy-Transfer Dynamics in Bacterial Reaction Centers.  J Phys Chem B (2018).
  • E Boulais, N P D Sawaya, R Veneziano, A Andreoni, J L Banal, T Kondo, S Mandal, S Lin, G S Schlau-Cohen, Neal Woodbury, H Yan, A Aspuru-Guzik, M. Bathe.  Programmed coherent coupling in a synthetic DNA-based excitonic circuit.  Nature Materials (2018).
Research Activity: 
Fall 2021
Course NumberCourse Title
BCH 494Special Topics
BIO 495Undergraduate Research
BCH 598Special Topics
Summer 2021
Course NumberCourse Title
BDE 792Research
Spring 2021
Course NumberCourse Title
PHY 792Research
BDE 792Research
PHY 799Dissertation
BDE 799Dissertation
Fall 2020
Course NumberCourse Title
BIO 495Undergraduate Research
Summer 2020
Course NumberCourse Title
BDE 792Research
Spring 2020
Course NumberCourse Title
CHM 584Internship
CHM 590Reading and Conference
BCH 592Research
CHM 592Research
BCH 593Applied Project
CHM 595Continuing Registration
BCH 599Thesis
CHM 599Thesis
PHY 792Research
BCH 792Research
CHM 792Research
BDE 792Research
CHM 795Continuing Registration
PHY 799Dissertation
BCH 799Dissertation
CHM 799Dissertation
BDE 799Dissertation
Fall 2019
Course NumberCourse Title
BIO 495Undergraduate Research
CHM 501Current Topics in Chemistry
CHM 584Internship
BCH 592Research
CHM 592Research
BCH 593Applied Project
CHM 593Applied Project
BCH 599Thesis
CHM 599Thesis
CHM 784Internship
CHM 790Reading and Conference
BCH 792Research
CHM 792Research
CHM 795Continuing Registration
CHM 799Dissertation
BCH 799Dissertation
Summer 2019
Course NumberCourse Title
CHM 584Internship
BCH 592Research
CHM 592Research
CHM 593Applied Project
CHM 599Thesis
CHM 784Internship
CHM 790Reading and Conference
PHY 792Research
BCH 792Research
CHM 792Research
CHM 795Continuing Registration
BCH 799Dissertation
CHM 799Dissertation
Spring 2019
Course NumberCourse Title
CHM 584Internship
CHM 590Reading and Conference
BCH 592Research
CHM 592Research
CHM 593Applied Project
BCH 593Applied Project
CHM 595Continuing Registration
BCH 599Thesis
CHM 599Thesis
CHM 790Reading and Conference
PHY 792Research
BDE 792Research
CHM 792Research
BCH 792Research
CHM 795Continuing Registration
PHY 799Dissertation
BCH 799Dissertation
CHM 799Dissertation
BDE 799Dissertation
Fall 2018
Course NumberCourse Title
BIO 495Undergraduate Research
CHM 501Current Topics in Chemistry
CHM 584Internship
BCH 592Research
CHM 592Research
BCH 593Applied Project
CHM 593Applied Project
BCH 599Thesis
CHM 599Thesis
CHM 784Internship
CHM 790Reading and Conference
BCH 792Research
CHM 792Research
CHM 795Continuing Registration
CHM 799Dissertation
BCH 799Dissertation
Summer 2018
Course NumberCourse Title
CHM 584Internship
CHM 592Research
BCH 592Research
CHM 593Applied Project
CHM 599Thesis
CHM 784Internship
CHM 790Reading and Conference
PHY 792Research
CHM 792Research
BCH 792Research
CHM 799Dissertation
BCH 799Dissertation
Spring 2018
Course NumberCourse Title
BCH 462General Biochemistry
CHM 584Internship
CHM 590Reading and Conference
CHM 592Research
BCH 592Research
CHM 593Applied Project
BCH 593Applied Project
CHM 595Continuing Registration
BCH 599Thesis
CHM 599Thesis
CHM 790Reading and Conference
CHM 792Research
PHY 792Research
BCH 792Research
CHM 795Continuing Registration
PHY 799Dissertation
BCH 799Dissertation
CHM 799Dissertation
Fall 2017
Course NumberCourse Title
BCH 462General Biochemistry
BIO 495Undergraduate Research
CHM 501Current Topics in Chemistry
CHM 584Internship
BCH 592Research
CHM 592Research
BCH 593Applied Project
CHM 593Applied Project
BCH 599Thesis
CHM 599Thesis
CHM 784Internship
CHM 790Reading and Conference
BCH 792Research
CHM 792Research
CHM 795Continuing Registration
PHY 799Dissertation
CHM 799Dissertation
BCH 799Dissertation
Summer 2017
Course NumberCourse Title
CHM 584Internship
CHM 592Research
BCH 592Research
CHM 593Applied Project
CHM 599Thesis
CHM 784Internship
CHM 790Reading and Conference
PHY 792Research
CHM 792Research
BCH 792Research
CHM 799Dissertation
BCH 799Dissertation
Spring 2017
Course NumberCourse Title
BCH 462General Biochemistry
BIO 495Undergraduate Research
CHM 584Internship
CHM 590Reading and Conference
CHM 592Research
BCH 592Research
CHM 593Applied Project
BCH 593Applied Project
CHM 595Continuing Registration
BCH 599Thesis
CHM 599Thesis
CHM 790Reading and Conference
CHM 792Research
BCH 792Research
PHY 792Research
CHM 795Continuing Registration
PHY 799Dissertation
BCH 799Dissertation
CHM 799Dissertation
Service: 
  • Global Institute of Sustainability, Senior Sustainability Scientist (2014 - 2999)
  • Center for Innovations in Medicine; Biodesign Institute at ASU, co-Director (2011 - 2999)
  • Global Institute of Sustainability, Senior Sustainability Scientist (2011 - 2999)
  • Global Institute of Sustainability, Senior Sustainability Scientist (2011 - 2999)
  • The Biodesign Institute at ASU, Executive Committee, member (2014 - 2999)
  • Mesa Biotech Academy, guest presenter (2012 - Present)
  • NSF MCB panel, panel member (2011 - Present)
  • CTE Biotech Highschool, guest presenter (2011 - Present)
  • Peggy Payne Academy at McClintock High School, guest speaker (2010 - Present)
  • Biodesign Institute Personnel Committee, member (2007 - Present)
  • Chemistry Advisory Committee, member (2006 - Present)
  • IGERT Program in Biomolecular Nanotechnology, Director (2006 - Present)
  • NSF Biophysics Panel, Panel Member (2006 - Present)
  • NSF Biophysics Panel, Panel member (2006 - Present)
  • NSF IGERT Panel, Member (2006 - Present)
  • NSF-MPS-MCB Joint Review Panel, Panel Member (2006 - Present)
  • NSF-MPS-MCB Joint Review Panel, Panel Member (2006 - Present)
  • Regents' Professor Nominating Committee, Chair (2006 - Present)
  • Biomolecular Nanotechnology, NSF, IGERT, Director (2000 - Present)
  • Department of Chemistry, Awards committee, Chair (2014 - 2015)
  • Department of Chemistry, Search committee, organic chemistry, member (2014 - 2015)
  • Department of Chemistry, search committee, biochemistry, member (2014 - 2015)
  • NSF Physics of Life Panel, Panel Member (2014 - 2014)
  • The Biodesign Institute at ASU, Directorate member (2014 - 2014)
  • AZ Science Center, Speaker (2014 - 2014)
  • NSF Engineering Biocatalyst Panel, Panel Member (2014 - 2014)
  • NSF MCB panel, Panel Member (2014 - 2014)
  • Search Committee, Chemistry, Biomimetic position, member (2013 - 2014)
  • NSF Physics of Life Panel, Panel Member (2014 - 2014)
  • Center for Innovation in Medicine, Biodesign, Co-director (2013 - 2013)
  • NSF Engineering Catalyst Panel, Panel member (2012 - 2012)
  • NSF Physics of Life Panel, Panel member (2012 - 2012)
  • The Biodesign Institute at ASU, Directorate member (2012 - 2012)
  • NSF Physics of Life panel, Panel member (2012 - 2012)
  • The Biodesign Institute at ASU, Directorate member (2011 - 2011)
  • The Biodesign Institute, Chief Scientific Officer (2011 - 2011)
  • Peggy Payne Academy at McClintock High School, Monthly Guest Speaker (2010 - 2011)
  • Biodesign Institute at ASU, Chief Scientific Officer (2010 - 2010)
  • Biodesign Institute at ASU, Deputy Director (2008 - 2010)
  • Spirit of the Senses, Presenter (2010 - 2010)
  • ASU Biodesign Institute AzTE/Biodesign, Committee (2009 - 2009)
  • ASU Biodesign Intercenter Biosignatures Committee, member (2009 - 2009)
  • ASU Biodesign Synergy Committee, member (2009 - 2009)
  • ASU Biological Design PhD. Program, Executive Committee (2009 - 2009)
  • ASU Biological Physics Faculty, member (2009 - 2009)
  • Center for Bioenergy & Photosynthesis Executive Committee, member (2009 - 2009)
  • Center for BioOptical Nanotechnology, Biodesign Institute at ASU, Director (2004 - 2009)
  • Spirit of the Senses speaker, Presenter (2009 - 2009)
  • President’s Community Enrichment Program, Presenter (2009 - 2009)
  • Chair search committee, member (2006 - 2006)
  • American Chemical Society, Panel Member (2006 - 2006)
  • Biodesign Institute Personel Committee, Chair (2006 - 2006)
  • Center for BioOptical Nanotechnology, The Biodesign Institute, Director (2006 - 2006)
  • Junior Faculty Committee Member, Chair (2006 - 2006)
  • Junior Faculty Mentor, mentor of Chaput, Ghirlanda, Wachter, Yan, Levitus (2006 - 2006)
  • Photochemistry and Photobiology, Associate Editor (2002 - 2006)
  • Regent's Professors Nominating Committee, Chair (2006 - 2006)
  • KAET Channel 8- HORIZION, Guest (2006 - 2006)
  • Search Committee for Department Chair, member (2005 - 2006)
  • Personnel Committee, Chair (2005 - 2006)
  • Marlyn Nutraceuticals v. Wong, Expert Witness (2006 - 2006)
  • National Academy of Science Workshop I - Chemical Imaging Committee, Member (2005 - 2005)
  • Excecutive committee, Photosynthesis Center, member (2003 - 2005)
  • Executive committee, The Biodesign Institute, member (2003 - 2005)
  • Radiation Protection Committee, Member (2003 - 2005)
  • NSF MPS-MCB Joint Review Panel, Panel Member (2005 - 2005)
  • National Academy of Science Workshop IV- Chemical Imaging Committee, Member (2005 - 2005)
  • National Academy of Science Workshop III - Chemical Imaging Committee, Member (2005 - 2005)
  • National Academy of Science Workshop II - Chemical Imaging Committee, Member (2005 - 2005)
  • American Chemical Society, Panel Member "Molecular Basis of Life" (2004 - 2004)
  • Awards Committee, member (2003 - 2004)
  • NSF Joint grant review panel on Biophysics, panel member (2003 - 2004)
  • Connolly Middle School, presenter (2003)
  • Personnel committee, member (2003)
  • search committee, chair (2003)
  • NSF RTG Optical Biomolecular Dev. Program, Director (1996 - 2002)
  • ASU Biodesign Institute AzTE/Biodesign, Committee (Present)
  • ASU Biodesign Institute Chromatin Committee, Co-chair (Present)
  • ASU Biodesign Intercenter Biosignatures Committee, member (Present)
  • ASU Biodesign Synergy Committee, member (Present)
  • ASU Biological Design Ph.D. Program, Executive Committee (Present)
  • ASU Biological Physics Faculty, member (Present)
  • Center for Bioenergy & Phtosynthesis Executive Committee, member (Present)
  • NSF Biophysics Panel, Panel Member (Present)
Expertise Areas: 
Biochemistry
Biophysics
Photosynthesis
Physical Chemistry