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Abhishek Shrivastava

Assistant Professor
Faculty, TEMPE Campus, Mailcode 6101
Assistant Professor
Faculty, TEMPE Campus, Mailcode 6101
Assistant Professor
Faculty, TEMPE Campus, Mailcode 6101
Biography: 

Abhishek Shrivastava develops experimental and computational tools to solve curiosity-driven questions related to the microbiome, biofilms, collective motion, chemotaxis, molecular motors, and protein secretion. One major focus of the Shrivastava lab is to find the factors that shape spatial structure of human microbial communities. They found that motile microbes of that are abundant in the human oral microbiome carry other non-motile bacteria as cargo and shape developing biofilms. Many recent reports show that changes in the human microbiome correlate with the occurrence of periodontal disease, oral and colorectal cancers, obesity, diabetes and inflammatory bowel disease. The Shrivastava lab aims to find why and how the microbiome correlates with the above diseases and how they can use this information to design therapeutic strategies.

Another major focus of the Shrivastava lab is a molecular rack and pinion machinery that couples with a bacterial Type 9 secretion system (T9SS) and enables bacterial surface navigation. Recently, they found that at the core of the T9SS is a novel rotary motor that is driven by a proton motive force. Until now, only three classes of ion-driven biological rotary motors are known: ATP synthase, the bacterial flagellar motor, and the T9SS motor. We know that the T9SS is composed of 19 different proteins but how the nuts and bolts work together to form an actively driven machinery is not clear. The Shrivastava lab aims to understand the design principles of this incredible molecular machine.

Education: 
  • Postdoctoral Fellow. Harvard University 2013-2019
  • Ph.D. University of Wisconsin-Milwaukee
Spring 2021
Course NumberCourse Title
MIC 493Honors Thesis
BIO 493Honors Thesis
MBB 493Honors Thesis
MIC 495Undergraduate Research
BIO 495Undergraduate Research
MBB 495Undergraduate Research
BIO 496Undergraduate Thesis
MIC 498Pro-Seminar
BIO 498Pro-Seminar
MIC 591Seminar
BIO 591Seminar
Spring 2020
Course NumberCourse Title
MIC 498Pro-Seminar
BIO 498Pro-Seminar
MIC 591Seminar
BIO 591Seminar
Presentations: 

Spring 2020  BIO/MIC 498 (U) and BIO/MIC 591 (G):  Programming for Biologists