Arul Mozhy Varman is an assistant professor of chemical engineering in the School for Engineering of Matter, Transport and Energy at Arizona State University. He received his doctorate in energy, environmental and chemical engineering from Washington University in St. Louis. He then worked as a postdoctoral researcher in the Department of Biomass Science and Conversion Technologies at Sandia National Laboratories, California.
Varman's research interests include metabolic engineering and synthetic biology for the sustainable production of chemicals, fuels, and pharmaceuticals from renewable resources.
Education
Ph.D. Energy, Environmental and Chemical Engineering, Washington University in St. Louis
M.S. Energy, Environmental and Chemical Engineering, Washington University in St. Louis
M.Tech. Chemical Engineering, Indian Institute of Technology Bombay
B.Tech. Chemical Engineering, Pondicherry University, India
Metabolic engineering and synthetic biology for the sustainable production of chemicals, fuels, and pharmaceuticals from renewable resources.
Publications
Selected Publications:
Varman AM, Follenfant R, Liu F, et.al. Hybrid phenolic-inducible promoters towards construction of self-inducible systems for microbial lignin valorization. Biotechnology for biofuels. 2018. 11 (1), 182.
Machas, M., Kurgan, G., Jha, A. K., et.al. Emerging tools, enabling technologies, and future opportunities for the bioproduction of aromatic chemicals. Journal of Chemical Technology & Biotechnology. 2018. 94: 38-52.
Wu W, Dutta T, Varman AM, et.al. Lignin valorization: two hybrid biochemical routes for the conversion of polymeric lignin into value-added chemicals. Scientific reports. 2017. 7.
Varman AM, He L, Follenfant R, et.al. Decoding how a soil bacterium extracts building blocks and metabolic energy from ligninolysis provides road map for lignin valorization. Proceedings of the National Academy of Sciences. 2016. 113 (40) E5802-E5811.
Hollinshead W*, Varman AM*, et.al. Boosting D-lactate production in engineered cyanobacteria using sterilized anaerobic digestion effluents. Bioresource Technology. 2014. 169: 462-467. * equal contribution.
Varman AM, He L, You L, et.al. Elucidation of intrinsic biosynthesis yields using 13C-based metabolism analysis. Microbial Cell Factories. 2014. 12:117.
Varman AM, Yu Y, You L, Tang YJ. Photoautotrophic production of D-lactic acid in an engineered cyanobacterium. Microbial Cell Factories. 2013. 12:117.
Varman AM, Xiao Y, Pakrasi H, Tang YJ. Metabolic engineering of Synechocystis sp. strain PCC 6803 for isobutanol production. Applied Environmental and Microbiology. 2013. 79(3): 908-914.
Xiao Y, Ruan Z, Liu Z, Wu SG, Varman AM, Liu Y, Tang YJ. Engineering Escherichia coli to convert acetic acid to free fatty acids, Biochemical Engineering Journal. 2013. 76: 60-69.
Yi X*, Feng X*, Varman AM*, et.al. Kinetic modeling and isotopic investigation of isobutanol fermentation by two engineered Escherichia coli strains. Industrial & Engineering Chemistry Research. 2012. 51 (49):15855–15863. * equal contribution.
Varman AM, Xiao Y, Leonard E, Tang YJ. Statistics-based model for prediction of chemical biosynthesis yield from Saccharomyces cerevisiae. Microbial Cell Factories. 2011. 10:45.
Colletti P, Goyal Y, Varman AM, et.al. Evaluating factors that influence microbial synthesis yields by regression with numerical and categorical variables. Biotechnology and Bioengineering. 2011. 108(4):893-901.