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Yuval Mazor

Yuval Mazor

Associate Professor,
School of Molecular Sciences
Other ASU affiliations
Applied Structural Discovery Researchers
Biodesign Center for Applied Structural Discovery
  • Yuval.Mazor@asu.edu
  • Biodesign A230B 1001 S. McAllister Ave. Tempe, AZ 85281
  • Mail code: 1604
    Campus: Tempe
  • ‌
Biography Research Teaching
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Long Bio

Yuval Mazor received his Ph.D. and M.Sc. from the department of microbiology and biotechnology in Tel Aviv University doing research on the genetic basis of telomere maintenance and epigenetic gene silencing. He then joined the lab of Professor Nathan Nelson, also in Tel Aviv University, where he studied the structure of large photosynthetic complexes in cyanobacteria and plants. 

Mazor is currently assistant professor at Arizona State University's School of Molecular Sciences and The Biodesign Institute. He has previously taught BCH598/BCH494, Photosynthesis Past and Present, as well as BCH 561, A Lecture on the Structural Biology of Photosynthetic Systems.

Education

Ph.D., Tel Aviv University, 2009

CV
Curriculum Vitae
Research Interests

Our primary focus is the structural biology of the membrane complexes involved in oxygenic photosynthesis. Photosynthetic organisms contain elaborate membrane systems called thylakoid membranes. In these membranes large reaction centers convert light into chemical energy. The photosynthetic reaction centers contain hundreds of light harvesting pigments, such as chlorophylls and carotenoids, oriented in a way which ensures efficient light harvesting. Around these reaction centers an elaborate system of antenna proteins and other enzymatic activities ensure a balance between beneficial chemical reactions, essential for the survival of the organism and unavoidable side reactions with toxic products. We want to develop a mechanistic understanding of these pathways based on structural, biochemical and genetic analysis. 

Publications
  1. Dobson, Z, Ahad, S, Vanlandingham, J, Toporik, H, Vaughn, N, Vaughn, M, Williams, D, Reppert, M, Fromme, P, Mazor, Y.  "The structure of photosystem I from a high-light-tolerant cyanobacteria," eLIFE, 2021.
  2. Toporik, H, Khmelnitskiy, A, Dobson, Z, Riddle, R, Williams, D, Lin, S, Jankowiak, R, Mazor, Y.  "The structure of a red-shifted photosystem I reveals a red site in the core antenna," Nature Communications, 2020 11 (1).
  3. Khmelnitskiy, A, Toporik, H, Mazor, Y, Jankowiak, R.  "On the Red Antenna States of Photosystem I Mutants from Cyanobacteria Synechocystis PCC 6803," Journal of Physical Chemistry B, 2020 124(39) 8504-5215.
  4. Toporik H, Li J, Williams D, Chiu PLC, Mazor Y. “The structure of the stress-induced photosystem I-IsiA antenna supercomplex”, Nature Structural and Molecular biology, 2019, 26(6):443-449.
  5. Marco P, Kozuleva M, Eilenberg H, Mazor Y, Gimeson P, Kanygin A, Redding K, Weiner I, Yacoby I.” Binding of ferredoxin to algal photosystem I involves a single binding site and is composed of two thermodynamically distinct events.”, Biochim Biophys Acta, 2018, 1859(4), 234.
  6. Mazor Y, Borovikova A, Caspy I, Nelson N. (2017) “The structure of plant photosystem I supercomplex at 2.6 Å resolution.” Nature Plants 3, 17014.
  7. Mazor Y, Borovikova A, Nelson N. (2015) “The structure of plant photosystem I super-complex at 2.8 Å resolution.” eLife, e07433.
  8. Mazor Y, Nataf D, Toporik H, Nelson N. (2014) “Crystal structures of virus-like photosystem I complexes from the mesophilic cyanobacterium Synechocystis PCC 6803.” eLife, e01496.
  9. Mazor Y, Greenberg I, Toporik H, Beja O, Nelson N. (2012) “The evolution of photosystem I in light of phage-encoded reaction centres.". Phil. Trans. R. Soc. B, 367(1608)3400:5.
  10. Mazor Y, Toporik H, Nelson N. (2012) "Temperature-sensitive PSII and promiscuous PSI as a possible solution for sustainable photosynthetic hydrogen production". BBA, 1817(8):1122-6.
  11. Omer S, Kovacs A, Mazor Y, Gophna U. (2009) "Complex integration does not impair fitness in an experimental model of lateral gene transfer." Mol Biol Evol, 27(11):2441-5.
  12. Mazor Y, Kupiec M. (2009) "Developmentally regulated MAPK pathways modulate heterochromatin in Saccharomyces cerevisiae". NAR, Vol. 37(14):4839-49.
  13. Parnas O, Zipin-Roitman A, Mazor Y, Liefshitz B, Ben-Aroya S, Kupiec M. (2009) "The ELG1 clamp loader plays a role in sister chromatid cohesion." PLoS ONE 4(5): e5497.
  14. Smolikov S, Mazor Y, Krauskopf A.  (2004) "ELG1, a regulator of genome stability, has a role in telomere length regulation and in silencing." Proc Natl Acad Sci U S A. 101: 1656-1661.
  15. Marco P, Kozuleva M, Eilenberg H, Mazor Y, Gimeson P, Kanygin A, Redding K, Weiner I, Yacoby I.  (2018) "Binding of ferredoxin to algal photosystem I involves a single binding site and is composed of two thermodynamically distinct events."  BBA 1859:  234.
Courses
2025 Summer
Course Number Course Title
CHM 392 Intro to Research Techniques
2025 Spring
Course Number Course Title
BCH 492 Honors Directed Study
BCH 493 Honors Thesis
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 392 Intro to Research Techniques
BCH 367 Elementary Biochemistry Lab
CHM 392 Intro to Research Techniques
CHM 492 Honors Directed Study
CHM 493 Honors Thesis
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
CHM 392 Intro to Research Techniques
BCH 392 Intro to Research Techniques
BCH 392 Intro to Research Techniques
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
CHM 392 Intro to Research Techniques
2024 Fall
Course Number Course Title
BCH 392 Intro to Research Techniques
BCH 492 Honors Directed Study
BCH 493 Honors Thesis
CHM 392 Intro to Research Techniques
CHM 492 Honors Directed Study
BIO 495 Undergraduate Research
CHM 493 Honors Thesis
BCH 392 Intro to Research Techniques
CHM 392 Intro to Research Techniques
2024 Spring
Course Number Course Title
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
2023 Fall
Course Number Course Title
BIO 495 Undergraduate Research
BCH 462 General Biochemistry
2023 Spring
Course Number Course Title
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
2022 Fall
Course Number Course Title
BIO 495 Undergraduate Research
BCH 462 General Biochemistry
2021 Fall
Course Number Course Title
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BIO 495 Undergraduate Research
BCH 462 General Biochemistry
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
2021 Spring
Course Number Course Title
BCH 462 General Biochemistry
2020 Fall
Course Number Course Title
BIO 495 Undergraduate Research
2020 Spring
Course Number Course Title
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
BCH 367 Elementary Biochemistry Lab
Expertise Areas
Biosystems Structure and Function
Genetics
Photosynthesis
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