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Jitendran Muthuswamy
- jit@asu.edu
- (480) 965-1599
- ISTB1 181A
Associate Professor
Faculty, TEMPE Campus, Mailcode 9709
Biography:
Jitendran (Jit) Muthuswamy is an associate professor in the School of Biological and Health System's Engineering. His research interests are in the areas of Microelectromechanical systems (MEMS) for Neural communication, and plasticity in the central nervous system. The engineering and neuroscience research efforts in his lab are primarily directed towards understanding and treating brain dysfunction. However, understanding of brain function and dysfunction is severely limited by the lack of technology that will reliably communicate with the cells in the brain for monitoring and intervention. Therefore, one of his main research interests is in the development of multi-functional Neural Prosthesis using MEMS (Micro-electromechanical Systems) technologies for precise tracking, communication, stimulation and control of neuronal function and dysfunction. Using these novel technologies in models of brain injury, Muthuswamy is interested in understanding the neurochemical and neuroelectrical dynamics that determine neurological outcome and the neuroprotective role of specific genes. There is a great potential for developing exciting new technology for enhancing repair and plasticity mechanisms in the brain after injury that will improve neurological outcomes and greatly enhance quality of lives. Projects are funded by the National Institutes of Health, the Whitaker foundation, Arizona Biomedical Research Foundation and the DARPA.
Education:
- Ph.D. Rensselaer Polytechnic Institute
- M.S. Rensselaer Polytechnic Institute
- B. Tech. Indian Institute of Technology, India
Publications:
- Jitendran Muthuswamy, M Okandan, A Gilletti, M Baker, T Jain. An array of microactuated microelectrodes for monitoring single neuronal activity in rodents. IEEE Trans Biomed Eng (2005).
- Jitendran Muthuswamy, M Okandan, N Jackson. Surface Micro-Machined Polysilicon Probes for Neurophysiology. J. Neurosci. Meth (2005).
- Jitendran Muthuswamy, M Okandan, T Jain. Electrostatic microactuators for precise positioning of Neural microelectrodes. IEEE Trans Biomed Eng (2005).
- M Khraiche, A Zhou, Jitendran Muthuswamy. Acoustic sensor for monitoring adhesion of Neuro-2A cells in real-time. J Neurosci. Meth (2005).
- Jain, T, Muthuswamy, Jitendran. Microsystems for spatiotemporal control over delivery of exogeneous molecules to adherent cells. (2005).
- Muthuswamy, Jitendran, MOkandan, M, Jackson, N. Steerable microelectrodes for neuronal communication. (2005).
- Muthuswamy, Jitendran, Okandan, M, Gilletti, A, Baker, M, Jackson, N. Movable microprobes for the brain. (2005).
- Muthuswamy, Jitendran, Okandan, M, Jackson, N. Neural microelectrodes that move. (2005).
- Saha, R, Gilletti, A, Muthuswamy, Jitendran. Tissue Micromotion Induced Stress Around Brain Implants. (2005).
- Saha, R, Muthuswamy, Jitendran. Mechanical stress in the brain tissue due to relative micromotion between implants and the brain. (2005).
- Wang, T, Ehteshami, G, Massia, S, Muthuswamy, Jitendran. GABA immobilized surfaces for assessing biofunctionality of GABA. (2005).
- Wang, T, Si, J, Muthuswamy, Jitendran. AN ACOUSTIC PLATFORM FOR STUDYING BINDING KINETICS OF NEUROTRANSMITTER -AMINOBUTYRIC ACID (GABA). (2005).
- A Zhou, Jitendran Muthuswamy. Acoustic biosensor for monitoring antibody immobilization and neurotransmitter GABA in real-time. Sensors & Actuators B:Chemical (2004).
- Muthuswamy, Jitendran. Biomedical Signal processing: An overview. Standard Handbook of Biomedical Engineering and Design (2003).
- Gilletti, A, Jain, T, Muthuswamy, Jitendran. Physiological Micromotion in the Somatosensory Cortex. (2003).
- Gilletti, A, Jain, T, Okandan, M, Muthuswamy, Jitendran. Overcoming brain micromotion in chronic neural implants. (2003).
- Khraiche, M, Muthuswamy, Jitendran. Real-time acoustic sensor for Neuronal adhesion. (2003).
- Khraiche, M, Zhou, A, Muthuswamy, Jitendran. Acoustic Sensors for Monitoring Neuronal Adhesion in Real-Time. (2003).
- Muthuswamy, Jitendran, Gilletti, A, Jain, T, Okandan, M. Microactuated Neural Probes to Compensate for Brain Micromotion. (2003).
- Stice, P, Panitch, A, Muthuswamy, Jitendran. Improved Viability of Chronic Neural Implants Using Thin Microelectrodes. (2003).
- Wang, T, Muthuswamy, Jitendran. Acoustic Immunosensor for Real-time Sensing of Neurotransmitter GABA. (2003).
- Wang, T, Muthuswamy, Jitendran. Real-time Sensing and Regeneration of GABA Sensor. (2003).
Research Activity:
- Muthuswamy,Jitendran*. Novel high-throughput technology for sorting differentiated iPSCs for regenerative medicine. (6/23/2014 - 6/22/2016).
- Muthuswamy,Jitendran*. Cyber-Biomedical Systems Curriculum (ASUF 30006199). INTEL CORP(1/1/2014 - 12/31/2015).
- Muthuswamy,Jitendran*. Autonomous MEMS probes for intracellular recording. HHS-NIH-NINDS(9/1/2013 - 8/31/2015).
- Muthuswamy,Jitendran*. Novel Bioactive Coatings for Chronically Implanted MEMS based Moveable Microelectrodes - PostDoc Arati Sridharan. HHS-NIH-NINDS(4/15/2011 - 4/14/2014).
- Muthuswamy,Jitendran*. Targeted RNAi Combinatorial Gene Suppression Using Multimodal Neurochip. AZ ADCC(7/1/2010 - 6/30/2012).
- Muthuswamy,Jitendran*. Single neuronal recordings using movable microphobes (See original title below). HHS-NIH-NINDS(9/15/2009 - 8/31/2013).
- Muthuswamy,Jitendran*. Single Neuronal Recordings Using Movable Microprobes. HHS-NIH-NINDS(3/1/2007 - 2/28/2013).
- Muthuswamy,Jitendran*. Micoractuated Microelectrodes to Assess Cortical Role in Memory Deficits. ABRC(9/1/2005 - 8/31/2008).
- Jung,Ranu*, Alexander,Gene Evans, He,Jiping, Helms Tillery,Stephen I, Hu,Jiuxiang, Marzke,Robert F, Massia,Stephen Paul, Matt,Kathleen Sharon, Moore,Michael Charles, Muthuswamy,Jitendran, Myhajlenko,Stefan, Neisewander,Janet Leigh, Nieman,Ronald A, Pauken,Christine Marie, Razdan,Anshuman, Vernon,Brent. PharmaScan 7016 In-Vivo SpectroscopyImaging System. HHS-NIH-NCRR(6/1/2005 - 5/31/2009).
- Muthuswamy,Jitendran*, Castaneda,Edward. Deep Brain Stimulation Using Microactuated Microprobes. HHS-NIH-NINDS(4/1/2005 - 3/31/2008).
- Muthuswamy,Jitendran*. Microactuated Microelectrode Arrays for Chronic Single Neuronal Monitoring. WHITAKER FDN(11/1/2004 - 10/31/2005).
- Muthuswamy,Jitendran*. Antibody Encapsulated Electrochemical Biosensor for GABA. INFRAMAT CORP(6/1/2003 - 4/26/2004).
- Muthuswamy,Jitendran*. MICROFABRICATED ELECTRODE POSITIONERS FOR STUDYING SOMATOSENSORY DEFICITS AFTER GLOBAL ISCHEMIA. WHITAKER FDN(5/1/2001 - 4/30/2004).
- Muthuswamy,Jitendran*. STEERABLE MICROFABRICATED MICROELECTRODE DRIVE. HHS-NIH-NINDS(9/21/2000 - 8/31/2004).
- He,Jiping*, Capco,David George, Farin,Gerald E, Hoppensteadt,Frank, Jassemidis,Leonidas Dimitrios, Kim,Bruce Chang-Shik, Lai,Ying-Cheng, Massia,Stephen Paul, Muthuswamy,Jitendran, Nielson,Gregory M, Panitch,Alyssa, Raupp,Gregory Bruce, Razdan,Anshuman, Si,Jennie. ADVANCED NEURAL IMPLANTS AND CONTROLS. DOD-DARPA(7/13/2000 - 5/31/2004).
| Spring 2022 | |
|---|---|
| Course Number | Course Title |
| BME 370 | Microcomputer Apps in BME |
| BME 492 | Honors Directed Study |
| BME 564 | Cyber Biomedical Systems |
| Fall 2021 | |
|---|---|
| Course Number | Course Title |
| ASU 101-BME | The ASU Experience |
| CSE 590 | Reading and Conference |
| Spring 2021 | |
|---|---|
| Course Number | Course Title |
| BME 370 | Microcomputer Apps in BME |
| BME 394 | Special Topics |
| BME 598 | Special Topics |
| Fall 2020 | |
|---|---|
| Course Number | Course Title |
| BME 394 | Special Topics |
| BME 492 | Honors Directed Study |
| BME 493 | Honors Thesis |
| BME 592 | Research |
| BME 599 | Thesis |
| BME 792 | Research |
| Spring 2020 | |
|---|---|
| Course Number | Course Title |
| BME 394 | Special Topics |
| BME 492 | Honors Directed Study |
| BME 493 | Honors Thesis |
| BME 592 | Research |
| BME 599 | Thesis |
| BME 792 | Research |
| Fall 2019 | |
|---|---|
| Course Number | Course Title |
| ASU 101-BME | The ASU Experience |
| BME 394 | Special Topics |
| BME 492 | Honors Directed Study |
| BME 493 | Honors Thesis |
| EEE 590 | Reading and Conference |
| BME 592 | Research |
| BME 598 | Special Topics |
| BME 599 | Thesis |
| BME 792 | Research |
| Spring 2019 | |
|---|---|
| Course Number | Course Title |
| BME 370 | Microcomputer Apps in BME |
| BME 394 | Special Topics |
| BME 492 | Honors Directed Study |
| BME 493 | Honors Thesis |
| BME 592 | Research |
| BME 599 | Thesis |
| BME 792 | Research |
| Fall 2018 | |
|---|---|
| Course Number | Course Title |
| ASU 101-BME | The ASU Experience |
| BME 394 | Special Topics |
| BME 492 | Honors Directed Study |
| BME 493 | Honors Thesis |
| BME 592 | Research |
| BME 598 | Special Topics |
| BME 599 | Thesis |
| BME 792 | Research |
| Summer 2018 | |
|---|---|
| Course Number | Course Title |
| BME 394 | Special Topics |
| Spring 2018 | |
|---|---|
| Course Number | Course Title |
| BME 370 | Microcomputer Apps in BME |
| BME 394 | Special Topics |
| BME 492 | Honors Directed Study |
| BME 493 | Honors Thesis |
| BME 592 | Research |
| BME 599 | Thesis |
| BME 792 | Research |
| Fall 2017 | |
|---|---|
| Course Number | Course Title |
| ASU 101-BME | The ASU Experience |
| BME 394 | Special Topics |
| BME 492 | Honors Directed Study |
| BME 493 | Honors Thesis |
| BME 598 | Special Topics |
Presentations:
- Muthuswamy, Jitendran, Castaneda, E, Okandan, M. Deep Brain Stimulation Using Microactuated Microprobes. Neural Interfaces Workshop, NINDS, NIH (Oct 2005).
- Muthuswamy, Jitendran, Okandan, M, Gilletti, A, Baker, M, Jackson, N, Jain, T. Movable microprobes for the brain. 3rd Annual IEEE EMBS Special Topic Conference on Microtechnologies in Medicine and Biology (May 2005).
- Saha, R, Gilletti, A, Muthuswamy, Jitendran. Tissue Micromotion Induced Stress Around Brain Implants. 3rd Annual IEEE EMBS Special Topic Conference on Microtechnologies in Medicine and Biology (May 2005).
- Khraiche, M, Muthuswamy, Jitendran. Acoustic Sensors for Monitoring Neuronal Adhesion in Real-Time. Annual meeting of BMES (Oct 2003).
- Wang, T, Muthuswamy, Jitendran. Real-time Sensing and Regeneration of GABA Sensor. Annual meeting of BMES (Oct 2003).
Service:
- IEEE Transactions on Neural Systems and Rehabilitation, Associate Editor (2006 - Present)
- Annual meeting of the Biomedical Engineering Society, Co-chair of session on "Neural signal and information processing, " (2005 - Present)
- Journal of Neurophysiology, Reviewer (2005 - Present)
- Friends of International students, Faculty advisor (2004 - Present)
- Graduate Committee, Member (2004 - Present)
- Annual meeting of the Biomedical Engineering society, Oct. 1-4, 2003, Co-chair of "Neural recording and stimulation," session (2003 - Present)
- Annual meeting of the IEEE Engineering in Medicine and Biology Society, Sept. 17-21, 2003, Co-chair of "Nano- and Micro-neurotechnology," session (2003 - Present)
- Chi Alpha Christian fellowship, Faculty advisor (2003 - Present)
- Annals of Biomedical Engineering, Reviewer (2000 - Present)
- Brain Research, Reviewer (2000 - Present)
- Experimental Brain Research, Reviewer (2000 - Present)
- IEEE Transactions on Biomedical Engineering, Reviewer (2000 - Present)
- Journal of Clinical Monitoring, Reviewer (2000 - Present)
- Faculty search committee (Neural and Tissue engineering), member (2005 - 2006)
- National Science Foundation, Member of IGERT pre-proposal review panel (2005 - 2005)
- Faculty search committee (Neural Prosthesis), member (2002 - 2004)