Brent Vernon

Biological and Health Systems Engineering

Associate Professor

Faculty, TEMPE Campus, Mailcode 9709

School of Life Sciences Interdisciplinary Graduate faculty

Faculty, TEMPE Campus, Mailcode 9709

Biography

Brent Vernon is an associate professor and undergraduate program chair in biomedical engineering in the School of Biological and Health Systems Engineering and the director of the Center for Interventional Biomaterials at Arizona State University. His research utilizes the principles of polymer science and chemistry to design and develop in situ gelling materials for drug delivery, tissue engineering and tissue reconstruction.

Curriculum Vitae

Education

Ph.D. Bioengineering, University of Utah 1999

Publications

Brennecka C, Preul MC, Vernon BL. In vitro delivery, cytotoxicity, swelling, and degradation behavior of a liquid-to-solid gelling polymer system for cerebral aneurysm embolization. Journal of Biomedical Materials Research, Part B (2012).
Overstreet D, Dutta D, Stabenfeldt SE*, Vernon BL*. Injectable hydrogels. Journal of Polymer Science Part B: Polymer Physics (2012).
Bearat H, Valdez Macias J, Vernon BL. Synthesis, characterization and properties of a physically and chemically gelling polymer system using poly(NIPAAm-co-HEMA-acrylate) and poly(NIPAAm-co-cysteamine). Journal of Biomaterials Science, Polymer Edition (2011).
Cui Z, Pauken C, Lee BH, Vernon BL. Degradation, cytotoxicity and biocompatibility of NIPAAm-based thermosensitive, injectable and bioresorbable polymer hydrogels. Journal of Biomedical Materials Research: Part A (2011).
Lee BH, Leon C, McLemore R, Macias JV, Vernon BL. Synthesis and characterization of thermo-sensitive radio-opaque poly(N-isopropylacrylamide-co-PEG-2-iodobenzoate). Journal of Biomaterials Science, Polymer Edition (2011).
Miller RB, McLaren AC, Leon CM, Vernon BL, McLemore R. Surfactant-stablized emulsion increases gentamicin elution from bone cement. Clinical Orthopaedics and Related Research (2011).
Riley CM, McLemore R, Preul MC, Vernon BL. Gelling process in reverse emulsion, in situ gelling polymeric materials formulated with liquid radio-opaque agents. Journal of Biomedical Materials Research Part B (2011).
Blakley B, Lee BH, Riley C, McLemore R, Vernon BL. Formulation and mechanical, kinetic and visual characterization of radio-opaque conjugated in situ-gelling materials. Journal of Biomedical Materials Research Part A (2010).
Overstreet DJ, Dhruv HD, Vernon BL. Bioresponsive copolymers of poly(N-isopropylacrylamide) with enzyme-dependent lower critical solution temperatures. Biomacromolecules (2010).
Henderson E, Lee BH, Cui Z, McLemore R, Brandon TA, Vernon BL. In vivo evaluation of temperature-sensitive polymer with time dependent LCST. Journal of Biomedical Materials Research (2009).
Leon C, Lee BH, Preul M, McLemore R, Vernon BL. Synthesis and characterization of radiopaque thermosensitive poly(NIPAAm-EDBEA-2,3,5-triiodobenzamide). Polymer International (2009).
McLaren AC, Nugent M, Economopoulos K, Kaul H, Vernon BL, McLemore R. Hand-mixed and premixed antibiotic-loaded bone cement have similar homogeneity. Clinical Orthopaedics and Related Research (2009).
McLemore R, Lee BH, Vernon BL. Surfactant effects on the kinetics of Michael-type addition reaction in reverse emulsion polymeric systems. Journal of Biomedical Materials Research (2009).
McLemore R, Robb SA, Lee BH, Caplan MR, Vernon BL. Michael-type addition reactions in NIPAAm-cysteamine copolymers follow second order rate laws with steric hindrance. Annals of Biomedical Engineering (2009).
Bae Hoon Lee, Bianca West, Brent Vernon. An In situ Injectable Physically and Chemically Gelling NIPAAm-based Copolymer System for Embolization. Biomacromolecules (2006).
R McLemore, M Preul, Brent Vernon. Controlling Delivery Properties of a Waterborne, In Situ-Forming Material. Journal of Biomedical Materials Research: Part B-Applied Biomaterials (2006).
B Lee, Brent Vernon. Copolymers of N-isopropylacrylamide, HEMA-lactate and acrylic acid with time-dependent lower critical solution temperature as a bioresorbable carrier. Polymer International (2005).
B Lee, Brent Vernon. In Situ-Gelling, Erodible N-isopropylacrylamide Copolymers. Macromolecular Biosciences (2005).
Brent Vernon, A Martinez. Gel strength and solution viscosity of temperature-sensitive, in situ-gelling polymers for endovascular embolization. Journal of Biomaterial Science: Polymer Edition (2005).
F Solis, R Weiss-Malik, Brent Vernon. Local monomer activation model for phase behavior and calorimetric properties of LCST gel-forming polymers. Macromolecules (2005).
M Birdno, Brent Vernon. Mechanical optimization of an arteriovenous malformation embolization material: A predictive model analysis. Annals of Biomedical Engineering (2005).
R McLemore, G Aerni, T Brandon, K Roy, Brent Vernon. Tubal sterilization using a water-borne poly(ethylene glycol) in situ cross-linking material: A non-surgical approach. Fertility and Sterility (2005).
Curd, T, Vernon, Brent, Pauken, C, Sundararajan, R. Optimization of Electroporation Parameters for Human Ovarian Cancer Cells. (2005).

Research Activity

Vernon,Brent*. An Agitation Pump to Facilitate EPIC Using Chemotherapy-loaded Microbeads. MAYO CLINIC SCOTTSDALE(7/16/2015 - 7/15/2016).
Vernon,Brent*. Surface-covering Gel for Broad-Spectrum Antimicrobial Protection in Open Fractures. (9/15/2014 - 12/31/2015).
Vernon,Brent*. Occular Drug Delivery System Development. (6/30/2014 - 6/29/2016).
Vernon,Brent*. In situ forming and resorbable antimicrobial-releasing gels for prevention of infection in total joint arthroplasty. (9/6/2013 - 8/31/2014).
Caplan,Michael Ryckman*, Vernon,Brent*, Vernon,Brent, Vernon,Brent*, Vernon,Brent*. Understanding Antimicrobial and Fluid Distribution in Orthopaedic Wounds for the Management of Infection and Trauma. Banner Good Sam(7/1/2011 - 6/30/2013).
Caplan,Michael Ryckman*, Vernon,Brent. Understanding Antimicrobial and Fluid Distribution in Orthopaedic Wounds for the Management of Infection and Trauma. Banner Good Sam(7/1/2010 - 6/30/2013).
Vernon,Brent*. Optimizing In Situ-gelling Emulsions for Arteriovenous Malformation and Aneurysm Embolization - year 3. AMER HEART ASSN(7/1/2009 - 6/30/2010).
Vernon,Brent*. Improved Materials for Endovascular Embolization. ABRC(7/1/2007 - 12/30/2010).
Vernon,Brent*. Optimizing In Situ-gelling Emulsions for Arteriovenous Malformation and Aneurysm Embolization. AMER HEART ASSN(7/1/2007 - 6/30/2009).
Vernon,Brent*. Cement Particle Morphology Research Study. DePuy(3/1/2007 - 6/30/2008).
Vernon,Brent*. Transmucosal Delivery of Erythromycin to Treat Gastroparesis. MAYO CLINIC SCOTTSDALE(7/1/2006 - 6/30/2009).
Jung,Ranu*, Alexander,Gene Evans, He,Jiping, Helms Tillery,Stephen I, Hu,Jiuxiang, Marzke,Robert F, Massia,Stephen Paul, Matt,Kathleen Sharon, Moore,Michael Charles, Muthuswamy,Jitendran, Myhajlenko,Stefan, Neisewander,Janet Leigh, Nieman,Ronald A, Pauken,Christine Marie, Razdan,Anshuman, Vernon,Brent. PharmaScan 7016 In-Vivo SpectroscopyImaging System. HHS-NIH-NCRR(6/1/2005 - 5/31/2009).
Vernon,Brent*, Pauken,Christine Marie. POLYMERS WITH TIME-DEPENDENT PROPERITIES FOR DRUG DELIVER. HHS-NIH-NIGMS(7/1/2003 - 6/30/2009).
Vernon,Brent*. pH Sensitive Microspheres for Oral Vaccine Delivery. MAYO CLINIC SCOTTSDALE(6/1/2003 - 5/31/2004).
Vernon,Brent*. pH Sensitive Microspheres for Oral Vaccine Delivery. BARROWS INSTIT/ST JOES HOSP(6/1/2003 - 5/31/2004).
Vernon,Brent*. In Situ Gelling Materials for Arteriovenous Malformation Treatment. MAYO CLINIC SCOTTSDALE(6/1/2003 - 12/31/2004).
Gust,John Devens*, Arntzen,Charles, Bieber,Allan Leroy, Blankenship,Robert E, Brophy,Colleen M, Brune,Daniel Charles, Capco,David George, Chandler,Douglas E, Francisco,Wilson Alex, Hu,Qiang, Jacobs,Bertram Lewis, Leket-Mor,Tsafrir Shlomo, Lindsay,Stuart, Lorson,Christian L, Massia,Stephen Paul, Misra,Rajeev, Moore,Ana L, Moore,Thomas Andrew, Panitch,Alyssa, Sommerfeld,Milton R, Trelease,Richard Norman, Vermaas,Willem F J, Vernon,Brent, Williams,Peter, Woodbury,Neal Walter. PURCHASE OF A MALDI-TOF MASS SPECTROMETER. NSF-MPS(2/1/2002 - 1/31/2005).
Vernon,Brent*. ADVANCED POLYMERS FOR ENDOVASCULAR EMBOLIZATION. AMER HEART ASSN(7/1/2001 - 6/30/2003).

Courses

Fall 2019
Course Number	Course Title
BME 382	Biomedical Prod Dsgn & Dev III
BME 394	Special Topics
BME 484	Internship
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 494	Special Topics
BME 592	Research
BME 598	Special Topics
BME 599	Thesis
BME 792	Research

Summer 2019
Course Number	Course Title
BME 200	Conservation Principles in BME

Spring 2019
Course Number	Course Title
BME 200	Conservation Principles in BME
BME 382	Biomedical Prod Dsgn & Dev III
BME 394	Special Topics
BME 484	Internship
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 592	Research
BME 599	Thesis
BME 792	Research

Fall 2018
Course Number	Course Title
ASU 101-BME	The ASU Experience
BME 394	Special Topics
BME 484	Internship
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 592	Research
BUS 593	Applied Project
BME 598	Special Topics
BME 599	Thesis
BME 792	Research

Summer 2018
Course Number	Course Title
BME 200	Conservation Principles in BME
BME 394	Special Topics

Spring 2018
Course Number	Course Title
BME 200	Conservation Principles in BME
BME 394	Special Topics
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 592	Research
BME 599	Thesis
BME 792	Research

Fall 2017
Course Number	Course Title
ASU 101-BME	The ASU Experience
BME 200	Conservation Principles in BME
BME 394	Special Topics
BME 492	Honors Directed Study
BME 493	Honors Thesis
BUS 593	Applied Project
BME 598	Special Topics

Summer 2017
Course Number	Course Title
BME 200	Conservation Principles in BME
BME 394	Special Topics

Spring 2017
Course Number	Course Title
BME 200	Conservation Principles in BME
BME 394	Special Topics
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 590	Reading and Conference
BME 593	Applied Project

Fall 2016
Course Number	Course Title
ASU 101-BME	The ASU Experience
BME 200	Conservation Principles in BME
BME 394	Special Topics
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 592	Research
BME 593	Applied Project

Summer 2016
Course Number	Course Title
BME 200	Conservation Principles in BME

Spring 2016
Course Number	Course Title
BME 200	Conservation Principles in BME
BME 394	Special Topics
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 590	Reading and Conference
BME 593	Applied Project

Fall 2015
Course Number	Course Title
ASU 101-BME	The ASU Experience
BME 200	Conservation Principles in BME
BME 394	Special Topics
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 593	Applied Project

Summer 2015
Course Number	Course Title
BME 200	Conservation Principles in BME

Spring 2015
Course Number	Course Title
BME 200	Conservation Principles in BME
BME 394	Special Topics
BME 492	Honors Directed Study
BME 493	Honors Thesis
BME 590	Reading and Conference
BME 593	Applied Project

Presentations

McLemore, R, Preul, M, Vernon, Brent. Controlling in situ gelation of waterborne, phase-segregated precursors for vascular embolization. 2005 BMES Annual Meeting (Oct 2005).
Curd, T, Vernon, Brent, Pauken, C, Sundararajan, R. Optimization of Electroporation Parameters for Human Ovarian Cancer Cells. Electrostatics Society of America 2005 Annual Meeting (Jun 2005).
Cui, Z, Lee, B, Vernon, Brent. N-isopropylacrylamide copolymer with dimethyl-gamma-butryolactone acrylate with hydrolysis-dependent lower critical solution temperature. 2005 MRS Spring Meeting (Mar 2005).
Solis, F, Larance, J, Weiss-Malik, R, Vernon, Brent. Experimental determination and modeling of phase and calorimetric properties of gel-forming polymers with a lower critical solution temperature (LCST). 2005 MRS Spring Meeting (Mar 2005).

Service

Curriculum&Academic Programs, member (2007 - Present)
Harrington Department of Bioengineering Graduate Program, Chair (2006 - Present)
Faculty Search Committee, Chair (2005 - Present)
Faculty Senate, Member (2005 - Present)
Advanced Functional Materials, Referee (2005 - Present)
Biomaterials, Referee (2005 - Present)
Journal of Physical Chemistry, Referee (2005 - Present)
Polymer, Referee (2005 - Present)
Chemistry of Materials, Referee (2005 - Present)
Institutional Use and Care of Animals Committee (IUCAC), Member (2005 - Present)
Journal of the American Chemical Society, Referee (2005 - Present)
Biomacromolecules, Referee (2004 - Present)
Annals of Biomedical Engineering, Referee (2004 - Present)
Advanced Materials, Referee (2004 - Present)
ASTM International, Member (2003 - Present)
Chemical Inventory Lab Implementation Team, Member (2003 - Present)
Sci-Quest Chemical Inventory Focus Group, Member (2003 - Present)
Mesa Unified School District, Science Fair Judge (2002 - Present)
Materials Research Society, Member (2002 - Present)
Society for Biomaterials, Member (2000 - Present)
American Chemical Society, Member (1998 - Present)
Controlled Release Society, Member (1998 - Present)
Biomedical Engineering Society, Member (1996 - Present)
Graduate Committee, Member (2003 - 2006)
Society of Biomaterials Drug Delivery Special Interest Group, Reporter (2004 - 2005)

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Brent Vernon