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Carolyn Compton
- Carolyn.Compton@asu.edu
- (480) 965-8060
- School of Life Sciences, LSC 278 427 E Tyler Mall Tempe
Biography:
Dr. Carolyn Compton is an academic pathologist specializing in gastrointestinal disease and is board certified in both anatomic and clinical pathology. She is a professor of Life Sciences at Arizona State University and a professor of laboratory medicine and pathology at the Mayo Clinic. She is also an adjunct professor of pathology at both the University of Arizona and Johns Hopkins University. She is the Chief Medical Officer of the National Biomarkers Development Alliance, a member of the Biodesign Institute at ASU, and the Chief Medical Officer of the Complex Adaptive Systems Institute. She is a former professor of pathology at Harvard Medical School, chief of Gastrointestinal Pathology at Massachusetts General Hospital and pathologist-in-chief of the Boston Shriners Children’s Hospital. More recently she has served as the CEO and president of the Critical Path Institute (2012), the director of Biorepositories and Biospecimen Research and the Innovative Molecular Analysis Technologies program at the National Cancer Institute (2005-2011), and the Strathcona Professor and chair of the Department of Pathology at McGill University and pathologist-in-chief of the McGill University Health Center (2000-2005). She is a past chair of the Cancer Committee of the College of American Pathologists and the immediate past chair of the American Joint Committee on Cancer (AJCC). Currently, she is the chair of the Precision Medicine Core of the AJCC and chair of the Pre-analytics for Precision Medicine Project Team at the College of American Pathologists. She has authored more than 500 scientific manuscripts, review articles, books and chapters.
Education:
- Ph.D..Harvard Graduate School of Arts & Sciences 1977
- M.D. Harvard Medical School 1977
- B.A. Bryn Mawr College 1969
Google Scholar URL:
Research Interests:
extracellular vesicles, preanalytics, colon cancer, medical prediction, cancer staging, biomarker development
Research Group:
Multiplexed in-solution serological test for SARS-CoV-2, human coronaviruses and other respiratory pathogens
Self-actualized Biopsy Integrity Management System Ensuring Pathological Accuracy
Publications:
- GTEx Consortium. The genotype-Tissue Expression (GTEx) Project. NatGenetics 2013;45:580-5.
- Goldman M, Compton C, Mittleman BB. Public-private Partnerships as Driving Forces in the Quest for Innovative Medicines. Clin Transl Med 2013;2:2.
- Mucci NR, Moore HM, Brigham LE, Goldthwaite CA, Little AR, Lockhart NC, Scott MP, Struewing JP, Vincent Sl, Compton CC, for the cancer Human Biobank (caHUB). Acquisition of Normal Tissue Subgroup, National Cancer Institute Biopreservation and Biobanking. 2013 Apr;11:77-82.
- Hayes DF, Allen J, Compton C, Gustavsen G, Leonard DGB, McCormack R, Newcomer L, Pothier K, Ransohof D, Schilsky RL, Sigal E, Taube SE, Tunis SR. Breaking a Vicious cycle. Science Transl Med 2013;5:1-7.
- Warren RS, Atreya CE, Niedzwiecki D, Weinberg V, Donner DB, Mayer RJ, Goldberg RM, Compton C, Zuraek MB, Ye X, Saltz LB, Bertagnolli MM. Association of TP53 Mutational Status and Gender with Survival After Adjuvant Treatment for Stage III Colon Cancer: Results of CALGB 89803. Clin Cancer Research 2013 Epub ahead of print.
- Compton CC, Byrd DR, Garcia-Aguilar J, Kurtzman SH, Olawaiye A, Washington MK (eds). AJCC Staging Atlas. 2nd Edition. A Companion to the seventh Editions of the AJCC Staging Manual and Handbook.. New York, Springer, 2012.
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- 243. Webber C, Gospodarowicz M, Sobin LH, Greene FL, Masson MD, Compton C, Brierley J, Groome PA. Improving the TNM classification: Findings from a 10-year continuous literature review. Int J Cancer (2014).
- 244. Barker AD, Compton CC, Poste G. The National Biomarker Development Alliance accelerating the translation of biomarkers to the clinic. Biomark Med (2014).
- 245. David KA, Unger FT, Uhlig P, Juhl H, Moore HM, Compton C, Nashan B, Dörner A, de Weerth A, Zornig C. Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue. Oncotarget (2014).
- Webber C, Gospodarowicz M, Sobin LH, Wittekind C, Greene FL, Mason MD, Compton C, Brierley J, and Groome PA. Improving the TNM classification: findings from a 10-year continuous literature review. Int J Cancer (2014).
- Goldman M, Compton C, Mittleman BB. Public-private Partnerships as Driving Forces in the Quest for Innovative Medicines. Clin Transl Med (2013).
- Groelz D, Sobin L, Branton P, Compton C, Wyrich R, Rainen L. Non-formalin fixative versus formalin-fixed tissue: A comparison of histology and RNA quality. Exp Mol Pathol (2013).
- GTEx Consortium. The genotype-Tissue Expression (GTEx) Project. Nat Genetics (2013).
- Hayes DF, Allen J, Compton C, Gustavsen G, Leonard DGB, McCormack R, Newcomer L, Pothier K, Ransohof D, Schilsky RL, Sigal E, Taube SE, Tunis SR. Breaking a Vicious Cycle. Transl Med (2013).
- Mucci NR, Moore HM, Brigham LE, Goldthwaite CA, Little AR, Lockhart NC, Scott MP, Struewing JP, Vincent Sl, Compton CC, for the cancer Human Biobank (caHUB). Acquisition of Normal Tissue Subgroup, National Cancer Institute. Biopreservation and Biobanking (2013).
- Warren RS, Atreya CE, Niedzwiecki D, Weinberg V, Donner DB, Mayer RJ, Goldberg RM, Compton C, Zuraek MB, Ye X, Saltz LB, Bertagnolli MM. Association of TP53 Mutational Status and Gender with Survival After Adjuvant Treatment for Stage III Colon Cancer: Results of CALGB 89803. Clin Cancer Research (2013).
| Spring 2022 | |
|---|---|
| Course Number | Course Title |
| BIO 394 | Special Topics |
| BIO 492 | Honors Directed Study |
| HON 493 | Honors Thesis |
| BIO 493 | Honors Thesis |
| BIO 494 | Special Topics |
| Fall 2021 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
| BIO 394 | Special Topics |
| BIO 492 | Honors Directed Study |
| BIO 494 | Special Topics |
| BIO 495 | Undergraduate Research |
| Spring 2021 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
| BIO 394 | Special Topics |
| BIO 492 | Honors Directed Study |
| BIO 493 | Honors Thesis |
| HON 493 | Honors Thesis |
| BIO 494 | Special Topics |
| Fall 2020 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
| BIO 492 | Honors Directed Study |
| HON 492 | Honors Directed Study |
| BIO 494 | Special Topics |
| BIO 495 | Undergraduate Research |
| Spring 2020 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
| BIO 394 | Special Topics |
| BIO 492 | Honors Directed Study |
| BIO 493 | Honors Thesis |
| BIO 494 | Special Topics |
| BIO 495 | Undergraduate Research |
| BIO 499 | Individualized Instruction |
| Fall 2019 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
| BIO 394 | Special Topics |
| BIO 492 | Honors Directed Study |
| BIO 498 | Pro-Seminar |
| Spring 2019 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
| BIO 394 | Special Topics |
| BIO 492 | Honors Directed Study |
| Fall 2018 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
| Spring 2018 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
| BIO 493 | Honors Thesis |
| BIO 591 | Seminar |
| Fall 2017 | |
|---|---|
| Course Number | Course Title |
| BIO 302 | Cancer-Mother of All Diseases |
Presentations:
- Compton CC. Biospecimens, Biomarkers and Genomics: What’s the Issue and Why Does It Matter?. NBDA Convergence Conference on Genomics (Dec 2014).
- Compton CC. Biospecimens, Biomarkers and Proteomics: What’s the Issue and Why Does It Matter. NBDA Convergence Conference on Proteomics (Dec 2014).
- Compton CC. Perspectives on Tissue Management Issues for Pathologist when Sending Tissue for Genomic Testing. College of American Pathologists Personalized healthcare Committee Meeting (Nov 2014).
- Compton CC. Challenge, Convergence, Complexity and Change in Cancer Care: Are We Ready?. American College of Surgeons Annual Meeting (Oct 2014).
- Compton CC. Biospecimens and Biomarkers: What Will It Take to Get to Precision Medicine?. World Congress on Skin Cancer (Sep 2014).
- Compton CC. Biobanking and Precision Medicine for Cancer. Leaders in Biobanking Congress (Sep 2014).
- Compton CC. The Right Stuff for Translational Biomedical Research: Garbage In, Garbage Out. Embracing Change: Enhancing Clinical Research Practices Conference (Sep 2014).
- Compton CC. The Crisis in Biomarker Development for Cancer: What Will It Take to Get to Precision Medicine?. Annual Research Day, University of Dundee, Scotland (Sep 2014).
- Compton CC. Leveraging Genomics In Oncology Clinical Development: Current And Future Benefits And Challenges. ASCO Annual Meeting (May 2014).
- Compton CC. Technology Development, Disruptive Innovation and the Future of Oncology. American radium Society Annual Meeting (Apr 2014).
- Compton CC. Accelerated FDA Approvals: What the Future Holds". CED Life Sciences Conference, Raleigh, SC (Feb 2014).
Honors / Awards:
Aesulapian Society – Harvard Medical School 1972
President’s Award – College of American Pathologist 2000
Frank W. Harman Award – College of American Pathologists 2003
Award of Merit – NIH (Group award for the Biorepository Coordinating Committee – chaired by Dr. Compton) 2006
Award of Merit – NIH (Group award for the Biorepository and Biospecimen Research – directed by Dr. Compton) 2006
America’s Top Physicians – Consumers’ Research Council of Americ 2007
America’s Top Pathologists – Consumers’ Research Council of America 2007
America’s Top Pathologists – Consumers’ Research Council of America 2008
America’s Top Pathologists – Consumers’ Research Council of America 2009
NIH Director’s Award - NIH Group Award for the NCI Community Cancer Centers Program 2009
America’s Top Pathologists – Consumers’ Research Council of America 2010
NIH Director’s Award - NIH Group Award for the NCI Community Cancer Centers Program 2011
NIH 2011 Gold Plain Language/Clear Communication Award - NIH 2011
Honorary Director Tissue Bank Consortium of Asia - Tissue Bank Consortium of Asia 2011
ISBER Award for Outstanding Achievement in Biobanking 2011
Women of Influence - Tucson, AZ
Pathology Power List – Top 100 pathologists of 30,000 worldwide
AACR Team Science Award
CFA Culling Memorial Lecture Award, National Society for Histopathology
ASU SUN (Serving University Needs) Award 2012, 2015 and 2016, 2020
Outstanding Medical Educator of the Year – University of Massachusetts Medical School
Outstanding Medical Educator of the Year – University of Massachusetts Medical School
Faculty Prize for Excellence in Teaching – Harvard Medical School
Faculty Prize for Excellence in Teaching – Harvard Medical School
Editorships:
Biopreservation and Biobanking Editorial Board
Journal of Molecular Nanotechnology and Nanomedicine Editorial Board
Immunome Research Journal Editorial Board
Gastrointestinal Cancer: Research and Therapy Editorial Board
Pharmacogenomics and Personalized Medicine Editorial Board
Extracellular Vesicles and Circulating Nucleic Acids Editorial Board
Professional Associations:
American Joint Committee on Cancer, Executive Committee
College of American Pathologists, Chair, Preanalytics for Precision Medicine Project Team
American Association of Cacer Research, Pathology Committee
Blood Profilig Atlas in Cancer (BloodPAC), CAP representative
Graduate Faculties / Mentoring History:
At ASU:
Chair, ASU PhD Thesis Committee: Eric Woolf
Faculty Advisor: ASU Chapter, American Women’s Medical Association
Faculty Advisor: ASU Chapter, Feed My Starving Children
Faculty Advisor: ASU Chapter, Stand Up To Cancer
PhD Thesis Committee – James Abraham
Faculty Director: The Making of a COVID Lab
Multidisciplinary Team Barrett Honors Project
Documentary Video: https://youtu.be/QKoko2QZIMM
PBS: https://azpbs.org/horizon/2021/06/asu-lab-stepped-up-to-help-az-through-the-pandemic/
Book
Work History:
Assistant Professor of Pathology – University of Massachusetts Medical School
Staff Pathologist and Acting Chief – Hospital Pathology, Department of Pathology, University of Massachusetts Medical Center
Director – Surgical Pathology, Autopsy Pathology, Residency Program, University of Massachusetts Medical Center
Assistant Professor of Medicine – University of Massachusetts Medical School, Worchester, MA
Assistant Pathologist – Department of Pathology, Massachusetts General Hospital, Boston, MA
Assistant Professor of Pathology – Harvard Medical School, Boston, MA
Chief of Gastrointestinal Pathology – Department of Pathology, Massachusetts General Hospital, Boston, MA
Assistant Histochemist – Department of Surgery, Massachusetts General Hospital, Boston, MA
Assistant Pathologist – Department of Pathology, Shriners Burns Hospital, Boston, MA
Associate Histochemist – Department of Surgery, Massachusetts General Hospital, Boston, MA
Associate Pathologist – Department of Pathology, Massachusetts General Hospital, Boston, MA
Associate Pathologist - Department of Pathology, Shriners Burns Hospital, Boston, MA
Associate Professor of Pathology – Harvard Medical School, Boston, MA
Pathologist – Department of Pathology, Massachusetts General Hospital, Boston, MA
Pathologist – Department of Pathology, Shriners Burns Hospital, Boston, MA
Histochemist – Department of Surgery, Massachusetts General Hospital, Boston, MA
Pathologist-in Chief, Director of Laboratories – Department of Pathology, Shriners Burns Hospital, Boston, MA
Consultant in Gastrointestinal Pathology – National Cancer Institute, Bethesda, MD
Professor of Pathology – Harvard Medical School, Boston, MA
Member/Pathologist – Dana Farber – Harvard Cancer Center
Professor of Oncology – Department of Oncology, McGill University, Montreal, Quebec, Canada
Strathcona Professor and Chairman – Department of Pathology, McGill University, Montreal, Quebec, Canada
Pathologist-in-Chief – McGill University Health Center, Montreal, Quebec, Canada
Director of Office of Biorepositories and Biospecimen Research - National Cancer Institute, Office of the Director
Pathologist – Department of Pathology, National Cancer Institute Clinical Center
Acting Director – Office of Technology and Industrial Relations, National Cancer Institute, Bethesda, MD
Executive Director – The Cancer Human Biobank, (caHUB®), National Cancer Institute, Bethesda, MD
Adjunct Professor of Pathology, Johns Hopkins School of Medicine
CEO and President – Critical Path Institute
CMO - National Biomarker Development Alliance
CMO – Complex Adaptive Systems Institute, ASU
Professor of Laboratory Medicine and Pathology, Mayo Clinic School of Medicine
Affiliated Scholar – ASU Center for Health Care Delivery and Policy
Honorary Professional Fellow, Queen Mary University London - Barts Hopsital
Service:
- Volitile Organic Compinds project of the Physical Sciences Oncology Centers program at the NCI, Scientific Advisor (2103 - 2021)
- Member Nominating Committee, American Joint Committee on Cancer Chair,, Chair (2013 - 2021)
- Feed My Starving Children, Faculty Sponsor (2013 - 2021)
- Precision Medicine Core Committee, American Joint Committee on Cancer, Chiar (2013 - 2021)
- American Joint Committee on Cancer, 8th Edition Cancer Staging Manual, Editorial Board (2012 - Present)
- International Union for Cancer Control, TNM Committee, USA AJCC representative and member (2008 - 2020)
- Accreditation Committee, Commission on Cancer, American College of Surgeons, Member (2008 - 2018)
- Institute of Medicine, National Academy of Sciences, Expert Reviewer for IOM study: Management of The Air Force Health Study Data and Specimens - Report to Congress (2014 - 2014)
- HealthTell, Board of Directors (2014 - 2014)
- American Joint Committee on Cancer, Editorial Board of the 8th Edition of the Cancer Staging Manual (2014 - 2014)
- American Joint Committee on Cancer, Executive Committee (2014 - 2014)
- Commission on Cancer, American College of Surgeons, Executive Committee member (2014 - 2014)
- Complex adaptive Systems Initiative, Chief Medical Officer (2014 - 2014)
- Feed My Starving Children, Faculty Sponsor (2014 - 2014)
- Indivumed GMBH, scientific consultant (2014 - 2014)
- International Union for Cancer Control, USA representative to the TNM Staging Committee (2014 - 2014)
- National Biomarker Development Alliance, Chief Medical Officer (2014 - 2014)
- Precision Medicine Core of the American Joint Committee on Cancer, Chair (2014 - 2014)
- Sun Devils for Public Health, Faculty Sponsor (2014 - 2014)
- National Human Genome Research Institute, Expert Advisory Panel (2014 - 2014)
- Summer Bridge Program, Lecturer/instrictor (2014 - 2014)
- Clinical Data Interchange Standards Consortium, Board of Directors (2012 - 2013)
- American Joint Committee on Cancer, Chairman (2008 - 2013)
Expertise Areas: