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Reed Cartwright

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Assistant Professor
Faculty, TEMPE Campus, Mailcode 5301
Assistant Professor
Faculty, TEMPE Campus, Mailcode 5301
Assistant Professor
Faculty, TEMPE Campus, Mailcode 5301
Assistant Professor
Faculty, TEMPE Campus, Mailcode 5301
Biography

Reed Cartwright is a geneticist who develops computational and statistical methodologies to explore evolutionary questions. Much of his research focuses on mutation — the raw material of evolution — and its impact on biological systems. Using techniques from biology, statistics and computer science, Cartwright and his research team use genetics- and genomics-based approaches to analyze mutation patterns in various organisms.

Cartwright develops software that detects mutations from the genetic data of related individuals, focusing on next-generation sequencing technology. He also develops programs for sequence simulation, alignment, phylogenetics, and population genetics analysis. Using various computational approaches to scientific programming, he and his collaborators develop new methods that improve our ability to understand the evolutionary relationships between organisms.

Education

 PhD, 2006, University of Georgia

Research Interests

computational evolutionary genomics, population genetics, biological theory, bioinformatics, biology education
 

Publications
  • Emily Thompson, Rachel Schwartz, Reed A. Cartwright. Analyzing the Genome with Statistics. The Pandas Thumb (2014).
  • Emily Thompson, Rachel Schwartz, Reed A. Cartwright. Phylogenomic Fallacies. The Pandas Thumb (2014).
  • Emily Thompson, Rachel Schwartz, Reed A. Cartwright. Phylogenomics: Deciphering a Billion-Piece Puzzle. The Pandas Thumb (2014).
  • Emily Thompson, Rachel Schwartz, Reed A. Cartwright. The Family Tree of Life. The Pandas Thumb (2014).
  • Avinash Ramu, Michiel J Noordam, Rachel S Schwartz, Arthur Wuster, Matthew E Hurles, Reed A Cartwright, Donald F Conrad. DeNovoGear: de novo indel and point mutation discovery and phasing. Nature Methods (2013).
  • Matthew B Hufford, Xun Xu, Joost Van Heerwaarden, Tanja Pyhäjärvi, Jer-Ming Chia, Reed A Cartwright, Robert J Elshire, Jeffrey C Glaubitz, Kate E Guill, Shawn M Kaeppler, Jinsheng Lai, Peter L Morrell, Laura M Shannon, Chi Song, Nathan M Springer, Ruth A Swanson-Wagner, Peter Tiffin, Jun Wang, Gengyun Zhang, John Doebley, Michael D McMullen, Doreen Ware, Edward S Buckler, Shuang Yang, Jeffrey Ross-Ibarra. Comparative population genomics of maize domestication and improvement. Nature Genetics (2012).
  • Reed A Cartwright, Julie Hussin, Jonathan EM Keebler, Eric A Stone, Philip Awadalla. A Family-Based Probabilistic Method for Capturing De Novo Mutations from High-Throughput Short-Read Sequencing Data. Statistical Applications in Genetics and Molecular Biology (2012).
  • Reed A. Cartwright. Lab Notes: The Alias Method for Sampling from Discrete Distributions. The Panda's Thumb (2012).
Research Activity
  • Cartwright,Reed Austin*. ABI Innovation: Identifying phylogenetically informative data from next generation sequencing. NSF-BIO(8/1/2014 - 7/31/2017).
  • Cartwright,Reed Austin*. Analysis of de novo mutation from sequencing of related individuals and cells. (5/8/2014 - 2/29/2016).
  • Cartwright,Reed Austin*. Mutation Accumulation in the Ciliate Tetrahymena Thermophila. UNIV OF HOUSTON(5/1/2013 - 4/30/2018).
Fall 2017
Course NumberCourse Title
BIO 340General Genetics
BIO 394Special Topics
BIO 492Honors Directed Study
MBB 495Undergraduate Research
BIO 499Individualized Instruction
Spring 2017
Course NumberCourse Title
MBB 493Honors Thesis
BIO 493Honors Thesis
Fall 2016
Course NumberCourse Title
BIO 189Life Sciences Career Paths
BIO 340General Genetics
BIO 492Honors Directed Study
MBB 495Undergraduate Research
BIO 499Individualized Instruction
Spring 2016
Course NumberCourse Title
MBB 493Honors Thesis
BIO 493Honors Thesis
BIO 494Special Topics
MBB 494Special Topics
BIO 499Individualized Instruction
MCB 598Special Topics
BIO 598Special Topics
EVO 598Special Topics
Fall 2015
Course NumberCourse Title
BIO 340General Genetics
BIO 492Honors Directed Study
MBB 495Undergraduate Research
BIO 499Individualized Instruction
Spring 2015
Course NumberCourse Title
BIO 493Honors Thesis
BIO 494Special Topics
BIO 499Individualized Instruction
BIO 598Special Topics
Fall 2014
Course NumberCourse Title
BIO 340General Genetics
BIO 492Honors Directed Study
MBB 495Undergraduate Research
BIO 499Individualized Instruction
Spring 2014
Course NumberCourse Title
BIO 493Honors Thesis
BIO 494Special Topics
BIO 495Undergraduate Research
BIO 598Special Topics
Fall 2013
Course NumberCourse Title
BIO 340General Genetics
BIO 492Honors Directed Study
Spring 2013
Course NumberCourse Title
BIO 493Honors Thesis
BIO 495Undergraduate Research
Presentations
  • Reed A. Cartwright, Rachel Schwartz, Megan Howell, Alexandra Merry. Strong Selection is Necessary for Repeated Evolution of Blindness in Cavefish. SOLS Symposium on Genomics (Dec 2014).
  • Reed A. Cartwright, Rachel Schwartz, Megan Howell, Alexandra Merry. Strong Selection is Necessary for Repeated Evolution of Blindness in Cavefish. Southern California Evolutionary Genetics & Genomics Meeting (Nov 2014).
  • Reed Cartwright and Melissa Wilson Sayres. Symposium --- Mutation: the Ultimate Source of Molecular Variation. Society for Molecular Biology and Evolution Conference (Jun 2014).
  • Rachel Schwartz and Reed Cartwright. Phylogenies from Next-Generation Sequence without Assembly or Alignment. Society forMolecular Biology and Evolution Conference (Jun 2014).
  • David Winter, Allan CHang, Ricardo Azevedo, Rebecca Zufall, Reed Cartwright. Directly measuring the rate of spontaneous mutation in Tetrahymena thermophila. Society forMolecular Biology and Evolution Conference (Jun 2014).
  • David Winter, Allan Chang, Ricardo Azevedo, Rebecca Zufall, Reed Cartwright. Accurate Detection of Mutations from Short-Read Sequencing. Evolution Meeting (Jun 2014).
  • Rachel Schwartz and Reed Cartwright. Inferring Phylogenies from Next-Generation Sequence Data. Evolution Meeting (Jun 2014).
  • Tara Furstenau and Reed Cartwright. The Effect of the Dispersal Distribution on Isolation-by-Distance in a Continuous Population. Evolution Meeting (Jun 2014).
  • Reed A. Cartwright and Donald F. Conrad. Probabilistic Models for De Novo Mutation Detection. Society forMolecular Biology and Evolution Conference (Jul 2013).
  • Nathan D. Palmer, Rachel S. Schwartz, Reed A. Cartwright. Sampling Tree-Space Effectively Using Distance Methods. Society for Molecular Biology and Evolution Conference (Jul 2013).
  • Kelly Harkins, Rachel S. Schwartz, Reed A. Cartwright, and Anne Stone. Phylogenomic Investigation of the Origins and Evolutionary History of Leishmania. Society forMolecular Biology and Evolution Conference (Jul 2013).
  • Nathan D. Palmer, Rachel S. Schwartz, and Reed A. Cartwright. Sampling Tree-Space Effectively Using Distance Methods. Evolution Conference (Jun 2013).
  • Rachel S. Schwartz and Reed A. Cartwright. Phylogenies from next-gen sequencing data without assembly. Evolution Conference (Jun 2013).
  • Reed A. Cartwright and Donald F. Conrad. Probabilistic Models for De Novo Mutation Detection. Biological Sequence Analysis and Probabilistic Models (Mar 2013).
  • Reed A. Cartwright. N/A. Teaching Phylogenetics to Undergraduates, Curriculum Development Workshop (Mar 2013).
  • Rachel Schwartz and Reed A. Cartwright. A mixture model for bias and error in genomic data reduces false positive identification of heterozygotes. Mechanisms of Protein Evolution (Feb 2013).
  • Akash Khare and Reed A. Cartwright. Estimating Indel Models via Simulation and Optimization. Mechanisms of Protein Evolution (Feb 2013).
  • Jessica Albanese and Reed A. Cartwright. LLAMBDA: Estimating Indel Rates and Length Distributions from a Multiple Sequence Alignment. Mechanisms of Protein Evolution (Feb 2013).
  • Reed A. Cartwright. Evolutionary Models of Mutation and Variation for Genomic Data. Molecular & Cellular Biology Colloquium and Genome@asu Joint Seminar (Nov 2012).
  • Patrick L Smith and Reed A. Cartwright. Hobnail: A program for identifying transposable element families from shotgun sequencing. Personal Genomes & Medical Genomics (Cold Spring Harbor Laboratory) (Nov 2012).
  • Reed A. Cartwright. Dawg 2.0: New Methods for Simulating Sequence Evolution. Society for Molecular Biology and Evolution Conference (Dublin, Ireland) (Jun 2012).
  • Reed A. Cartwright, Carolin Kosiol, and Alexandros Stamatakis. Symposium: Estimating and simulating models of molecular evolution. Society for Molecular Biology and Evolution Conference (Dublin, Ireland) (Jun 2012).
  • Reed A. Cartwright. Dawg 2.0: New Methods for Simulating Sequence Evolution. Mathematical and Computational Evolutionary Biology (Montpellier, France) (Jun 2012).
  • Reed A. Cartwright. Evolutionary Models of Mutation and Variation for Genomic Data. UC Davis Seminar, hosted by both the Genome Center and the Genetics Graduate Group (May 2012).
  • Reed A. Cartwright. N/A. SMBE Satellite Symposium on Phylomedicine (ASU) (Mar 2012).
  • Reed A. Cartwright. N/A. BioQUEST/SCALE-IT Curriculum Development Workshop (University of Tennessee) (Jan 2012).
Service
  • The FreeBSD Foundation, Maintainer of htslb port (2014 - Present)
  • The FreeBSD Foundation, Maintainer of samtools port (2014 - Present)
  • National Science Foundation, Panelist (2014 - Present)
  • Molecular Biology and Evolution, Reviewer (2014 - Present)
  • Comparative Genomics Faculty Search Committee, Member (2013 - Present)
  • CEMI Seminar, Host (2013 - Present)
  • CEMI Seminar, Host (2013 - Present)
  • SOLS Seminar, Host (2013 - Present)
  • CEMI Seminar, Host (2013 - Present)
  • The FreeBSD Foundation, Maintainer of Mafft Port (2012 - Present)
  • The FreeBSD Foundation, Maintainer of Mafft Port (2012 - Present)
  • The FreeBSD Foundation, Maintainer of Mafft Port (2012 - Present)
  • Space Committee in Biodesign, Member (2012 - Present)
  • Space Committee in Biodesign, Member (2012 - Present)
  • Space Committee in Biodesign, Member (2012 - Present)
  • TalkOrigins Foundation, Website Adminstrator (2011 - Present)
  • TalkOrigins Foundation, Website Adminstrator (2011 - Present)
  • TalkOrigins Foundation, Website Adminstrator (2011 - Present)
  • The Panda's Thumb (TalkOrigins Foundation), Managing Editor (2004 - Present)
  • The Panda's Thumb (TalkOrigins Foundation), Managing Editor (2004 - Present)
  • The Panda's Thumb (TalkOrigins Foundation), Managing Editor (2004 - Present)
  • Comparative Genomics Faculty Search Committee, member (2013 - 2014)