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Jeffrey Kleim

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SUM/WTR Faculty Research
Faculty, TEMPE Campus, Mailcode 9709
Faculty, TEMPE Campus, Mailcode 9709
Research Interests

Jeffrey Kleim studies how neural plasticity supports learning in the intact brain and “relearning” in the damaged or diseased brain. His research is directed at developing therapies that optimize plasticity in order to enhance recovery after stroke and Parkinson’s Disease.The brain is a highly dynamic organ that is capable of structural and functional reorganization in response to a variety of manipulations. This neural plasticity is the mechanism by which the brain encodes experience. My laboratory examines how plasticity within rat and human motor cortex supports learning in the intact brain and “relearning” after stroke. We use intracortical microstimulation in rats and transcranial magnetic stimulation in humans to examine how motor training alters the functional organization of motor cortex. This work has demonstrated that rehabilitation-dependent recovery of motor function after stroke is associated with a reorganization of movement representations in rodent motor cortex. Furthermore, there are specific behavioral and neural signals that drive both recovery and plasticity. These experiments are being used to test novel therapies for enhancing motor recovery in stroke patients.

Research Activity
Fall 2017
Course NumberCourse Title
BME 100Intro to Biomed Engineering
BME 394Special Topics
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
Summer 2017
Course NumberCourse Title
BME 394Special Topics
BIO 495Undergraduate Research
Spring 2017
Course NumberCourse Title
BME 100Intro to Biomed Engineering
BME 394Special Topics
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
BME 494Special Topics
BME 590Reading and Conference
BME 593Applied Project
NEU 598Special Topics
BME 598Special Topics
Fall 2016
Course NumberCourse Title
BME 100Intro to Biomed Engineering
BME 394Special Topics
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
BME 592Research
BME 593Applied Project
Summer 2016
Course NumberCourse Title
BME 394Special Topics
BME 484Internship
BIO 495Undergraduate Research
Spring 2016
Course NumberCourse Title
BME 100Intro to Biomed Engineering
BME 394Special Topics
BME 484Internship
BME 490Biomedical Engr Capstone II
BME 492Honors Directed Study
BME 493Honors Thesis
BME 494Special Topics
BME 590Reading and Conference
BME 593Applied Project
NEU 598Special Topics
BME 598Special Topics
Fall 2015
Course NumberCourse Title
BME 100Intro to Biomed Engineering
BME 394Special Topics
BME 417Biomed Engr Capstone Design I
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
BME 593Applied Project
Summer 2015
Course NumberCourse Title
BME 394Special Topics
BME 484Internship
BIO 495Undergraduate Research
Spring 2015
Course NumberCourse Title
BME 100Intro to Biomed Engineering
BME 394Special Topics
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
BME 494Special Topics
BME 590Reading and Conference
BME 593Applied Project
NEU 598Special Topics
BME 598Special Topics
Fall 2014
Course NumberCourse Title
BME 100Intro to Biomed Engineering
BME 235Physiology for Engineers
BME 394Special Topics
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
BME 593Applied Project
Summer 2014
Course NumberCourse Title
BME 394Special Topics
BME 484Internship
BIO 495Undergraduate Research
Spring 2014
Course NumberCourse Title
BME 100Intro to Biomed Engineering
BME 394Special Topics
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
BME 494Special Topics
BME 593Applied Project
NEU 598Special Topics
BME 598Special Topics
Fall 2013
Course NumberCourse Title
BME 100Intro to Biomed Engineering
ASU 101-BMEThe ASU Experience
BME 394Special Topics
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
BME 593Applied Project
Summer 2013
Course NumberCourse Title
BME 394Special Topics
BME 484Internship
BIO 495Undergraduate Research
Spring 2013
Course NumberCourse Title
BME 101Intro to BME I: Belief Systems
ASU 101-BMEThe ASU Experience
BME 102Intro to BME II
BME 103Intro to BME III
BME 394Special Topics
BME 484Internship
BME 492Honors Directed Study
BME 493Honors Thesis
BME 494Special Topics
BIO 495Undergraduate Research
BME 593Applied Project
NEU 598Special Topics
BME 598Special Topics