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Matthew Scotch

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Assoc Professor
Faculty, DTPHX Campus, Mailcode 6520
Assoc Professor
Faculty, DTPHX Campus, Mailcode 9020
Biography

Dr. Matthew Scotch is an Associate Professor in the Department of Biomedical Informatics and Assistant Director of the Biodesign Center for Environmental Security at Arizona State University. His research focuses on the theory and application of phylogeography to study the migration of zoonotic RNA viruses with a particular interest in influenza A viruses.  Work in his lab includes the integration, analysis, and presentation of viral genetics for public health/animal health surveillance.

Current projects include studying approaches to advance:

  • Phylogeography models in order to identify climate, population, and genetic factors that support viral spread. Funding: NIH/NLM R01LM012080
  • Geospatial metadata in virus sequence databases and approaches to include observation error for virus phylogeography. Funding: NIH/NIAID R01AI117011

 

Dr. Scotch’s lab is also interested in the molecular epidemiology of zoonotic viruses including the amplification and sequencing of influenza A genes for studying spread among avian and human hosts.

Dr. Scotch received a Masters in Biomedical Informatics from Columbia University, a PhD in Biomedical Informatics from the University of Pittsburgh, and a Masters of Public Health (MPH) from Yale University. He also did his postdoctoral training at Yale University.

Articles indexed in PubMed.

Research Interests
  • Bioinformatics for Public Health (systems that leverage molecular sequence data to support decision-making at health agencies)
  • Zoonotic disease surveillance (linking health data on animal and humans)
  • Phylogeography of zoonotic RNA viruses
  • Molecular epidemiology of zoonotic RNA viruses
  • Sequencing and analysis of the Influenza A genome
  • Geographical Information Systems (GIS)
  • Natural Language Processing (NLP)
Publications
  • Kane MJ, Price N, Scotch M, Rabinowitz P. Comparison of ARIMA and random forest time series models for prediction of avian influenza H5N1 outbreaks. BMC Bioinformatics (2014).
  • Scotch M, Lam TT, Pabilonia KL, Anderson T, Baroch J, Kohler D, DeLiberto TJ. Diffusion of influenza viruses among migratory birds with a focus on the Southwest United States. Infection Genetics Evolution (2014).
  • Beard R, Magee D, Suchard MA, Lemey P, Scotch M. Generalized Linear Models for Identifying Predictors of the Evolutionary Diffusion of Viruses. American Medical Informatics Association 2014 Joint Summits on Translational Science (2014).
  • Tahsin T, Rivera R, Beard R, Lauder R, Weissenbacher D, Scotch M, Wallstrom G, Gonzalez G. Natural language processing methods for enhancing geographic metadata for phylogeography of zoonotic viruses. Proceedings of the 2014 Workshop on Biomedical Natural Language Processing (BioNLP 2014) (2014).
  • Braithwaite RS, Scotch M. Using value of information to guide evaluation of decision supports for differential diagnosis: is it time for a new look?. BMC Med Inform Decis Mak (2013).
  • Scotch M, Baarson B, Beard R, Lauder R, Varman A, Halden RU. Examining the differences in format and characteristics of zoonotic virus surveillance data on state agency websites. J Med Internet Res (2013).
  • Scotch M, Mei C, Makonnen YJ, Pinto J, Ali A, Vegso S, Kane M, Sarkar IN, Rabinowitz P. Phylogeography of influenza A H5N1 clade 2.2.1.1 in Egypt. BMC Genomics (2013).
  • Scotch M, Mei C. Phylogeography of swine influenza H3N2 in the United States: Translational public health for zoonotic disease surveillance. Infect Genet Evol (2013).
  • Womack JA, Scotch M, Leung SN, Skanderson M, Bathulapalli H, Haskell SG, Brandt CA. Use of structured and unstructured data to identify contraceptive use in women veterans. Perspect Health Inf Manag (2013).
  • Rabinowitz PM, Galusha D, Vegso S, Michalove J, Rinne S, Scotch M, Kane M. Comparison of human and animal surveillance data for H5N1 influenza A in Egypt 2006-2011. PLoS One (2012).
  • Konovalov S, Scotch M, Post L, Brandt C. Biomedical informatics techniques for processing and analyzing web blogs of military service members. Journal of Medical Internet Research (2010).
  • Ohl M, Tate J, Duggal M, Skanderson M, Scotch M, Kaboli P, Vaughan-Sarrazin M, Justice A. Rural residence is associated with delayed care entry and increased mortality among veterans with human immunodeficiency virus infection. Medical Care (2010).
  • Rabinowitz PR, Scotch M, Conti LA. Animals as Sentinels: Using Comparative Medicine to Move Beyond the Laboratory. Institute for Laboratory Animal Research Journal (2010).
  • Scotch M, Duggal M, Brandt C, Lin Z, Shiffman R. Use of Statistical Analysis in the Biomedical Informatics Literature. Journal of the American Medical Informatics Association (2010).
  • Scotch M, Mei C, Brandt C, Sarkar IN, Cheung K. At the intersection of public-health informatics and bioinformatics: using advanced Web technologies for phylogeography. Epidemiology (2010).
  • Womack JA, Scotch M, Gibert C, Chapman W, Yin M, Justice AC, Brandt C. A comparison of two approaches to text processing: facilitating chart reviews of radiology reports in electronic medical records. Perspectives in Health Information Management (2010).
  • Liu A, Lee V, Galusha D, Slade MD, Diuk-Wasser M, Andreadis T, Scotch M, Rabinowitz PM. Risk factors for human infection with West Nile Virus in Connecticut: a multi-year analysis. Int J Health Geogr (2009).
  • Rabinowitz P, Scotch M, Conti L. Human and animal sentinels for shared health risks. Vet Ital (2009).
  • Scotch M, Odofin L, Rabinowitz P. Linkages between animal and human health sentinel data. BMC Vet Res (2009).
  • Boulos MN, Scotch M, Cheung KH, Burden D. Web GIS in practice VI: a demo playlist of geo-mashups for public health neogeographers. Int J Health Geogr (2008).
  • Cheung KH, Yip KY, Townsend JP, Scotch M. HCLS 2.0/3.0: health care and life sciences data mashup using Web 2.0/3.0. J Biomed Inform (2008).
  • Parmanto B, Paramita MV, Sugiantara W, Pramana G, Scotch M, Burke DS. Spatial and multidimensional visualization of Indonesia's village health statistics. Int J Health Geogr (2008).
  • Scotch M, Parmanto B, Monaco V. Evaluation of SOVAT: an OLAP-GIS decision support system for community health assessment data analysis. BMC Med Inform Decis Mak (2008).
  • Scotch M, Yip KY, Cheung KH. Development of grid-like applications for public health using Web 2.0 mashup techniques. Journal of the American Medical Informatics Association (2008).
  • Scotch M, Parmanto B, Monaco V. Usability Evaluation of the Spatial OLAP Visualization and Analysis Tool (SOVAT). Journal of Usability Studies (2007).
  • Scotch M, Parmanto B, Gadd CS, Sharma RK. Exploring the role of GIS during community health assessment problem solving: experiences of public health professionals. Int J Health Geogr (2006).
  • Parmanto B, Scotch M, Ahmad S. A framework for designing a healthcare outcome data warehouse. Perspect Health Inf Manag (2005).
  • Scotch M, Parmanto B. SOVAT: Spatial OLAP Visualization and Analysis Tool. HICSS-38 (2005).
  • Parmanto B, Scotch M. Mining Information from Mountains of Electronic Health Record: Unique Challenges and Solutions. Proceedings of AHIMA (2003).
  • Stetson PD, Johnson SB, Scotch M, Hripcsak G. The sublanguage of cross-coverage. Proc AMIA Symp (2002).
Research Activity
Summer 2017
Course NumberCourse Title
BMI 484Internship
BMI 584Internship
BMI 593Applied Project
BMI 792Research
BMI 799Dissertation
Spring 2017
Course NumberCourse Title
BMI 493Honors Thesis
BMD 502Foundations BMI Methods I
BMI 560Teachng Biomedical Informatics
BMI 570BMI Symposium
BMI 590Reading and Conference
BMI 593Applied Project
BMI 790Reading and Conference
BMI 792Research
BMI 799Dissertation
Fall 2016
Course NumberCourse Title
BMI 102Intro Public Hlth/Imagng Infor
BMI 492Honors Directed Study
MBB 495Undergraduate Research
BMI 560Teachng Biomedical Informatics
BMI 593Applied Project
BMI 792Research
BMI 799Dissertation
Summer 2016
Course NumberCourse Title
BMI 792Research
BMI 799Dissertation
Spring 2016
Course NumberCourse Title
BMD 502Foundations BMI Methods I
BMI 560Teachng Biomedical Informatics
BMI 592Research
BMI 593Applied Project
BMI 790Reading and Conference
BMI 792Research
Fall 2015
Course NumberCourse Title
BMI 102Intro Public Hlth/Imagng Infor
BMI 502Foundations BMI Methods I
BMI 560Teachng Biomedical Informatics
BMI 592Research
BMI 593Applied Project
BMI 792Research
BMI 799Dissertation
Summer 2015
Course NumberCourse Title
BMI 792Research
Spring 2015
Course NumberCourse Title
BMD 502Foundations BMI Methods I
BMI 560Teachng Biomedical Informatics
BMI 592Research
BMI 790Reading and Conference
Fall 2014
Course NumberCourse Title
HCD 501Health Stats Tools Health Env
BMI 502Foundations BMI Methods I
BMI 560Teachng Biomedical Informatics
BMI 592Research
BMI 799Dissertation
Spring 2014
Course NumberCourse Title
MIC 495Undergraduate Research
BMI 591Seminar
BIO 591Seminar
Fall 2013
Course NumberCourse Title
HCD 501Health Stats Tools Health Env
BMI 502Foundations BMI Methods I
Spring 2013
Course NumberCourse Title
BMI 591Seminar
BIO 591Seminar
Presentations
  • Matthew Scotch. A pipeline for virus phylogeography that accounts for geospatial observation error. 12th Annual Rocky Mountain Bioinformatics Conference (Dec 2014).
  • Matthew Scotch and Graciela Gonzalez. Text processing and geospatial uncertainty for phylogeography of zoonotic viruses. Webinar on NIH-funded projects on spatial uncertainty, surveillance research program (Oct 2014).
  • Matthew Scotch. Challenges and promises of bioinformatics for translational applications. Lecture to first-year medical students at UA-COM (Sep 2014).
  • Matthew Scotch. Tracking the spread of viruses. Spirit of the senses salon (Sep 2014).
  • Matthew Scotch and Daniel Magee. Phylogeographic generalized linear model for identifying predictors driving H5N1 diffusion within Egypt. Intelligent Systems for Molecular Biology (ISMB) (Jul 2014).
  • Matthew Scotch. Translational public health: using viral sequence data for zoonotic disease surveillance. Epi Presents! series (Apr 2014).
  • Matthew Scotch. Phylogeography of avian and human influenza in the Southwest United States. Influenza2013: One Influenza, One World, One Health, Oxford, United Kingdom (Sep 2013).
  • Matthew Scotch. Phylogeography of avian and human influenza in the southwest United States. 10th Annual Rocky Bioinformatics Conference (Dec 2012).
  • Matthew Scotch. Phylogeography of influenza A in human and avian species in the southwest United States. Molecular Epidemiology and Evolutionary Genetics of Infectious Disease (MEEGID)11 (Nov 2012).
  • Matthew Scotch. Public health informatics to support public health decision making. Society for Medical Decision Making Annual Meeting (Oct 2012).
  • Scotch M. Integrated Human-Animal Surveillance Systems for Emerging Threats to Health. Electronic Medical Records: How They Can Improve Animal Health conference (Nov 2010).
Service
  • Infection Genetics Evolution, Editorial Board (2014 - Present)
  • Influenza Research Database and Virus Pathogen Resource, Member, User Advisory Group (2014 - Present)
  • Infection, Genetics, and Evolution, Editorial Board (2013 - Present)
  • Influenza Research Database and Virus Pathogen Resource, Member, User Advisory Group (2013 - Present)
  • Biomedical Informatics Academic Program Committee, Member (2014 - 2014)
  • NIH/NLM Information Resource Grants to Reduce Health Disparities (G08), ZLM1 ZH-G 01, Reviewer (2014 - 2014)
  • Biomedical Informatics Admissions Committee, Chair (2014 - 2014)
  • NIH/NLM Special Emphasis Panel, ZLM1 ZH-C 01, Reviewer (2014 - 2014)
  • Biomedical Informatics Academic Program Committee, Member (2013 - 2013)
  • Biomedical Informatics Admissions Committee, Chair (2013 - 2013)
  • Biomedical Informatics Academic Program Committee, Member (2012 - 2012)
  • Biomedical Informatics Admissions Committee, Chair (2012 - 2012)
  • Biomedical Informatics Media Team, Member (2012 - 2012)
  • NIH/NLM Information Resource Grants to Reduce Health Disparities (G08), ZLM1 ZH-G 01, Reviewer (2012 - 2012)
  • NIH/NIAID, Bioinformatics Integration Support Contract (BISC), ZAI1-QV-I (C1), Reviewer (2012 - 2012)
  • Biomedical Informatics Admissions Committee, Chair (2011 - 2011)
  • American Medical Informatics Association, Public Health Informatics Working Group, Past Chair (2011 - 2011)
  • American Medical Informatics Association, Public Health Informatics Working Group, Chair (2009 - 2010)
  • American Medical Informatics Association, Student Working Group, Executive Committee, Member-at-Large (2008 - 2010)