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Karen Anderson

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Professor
Faculty, TEMPE Campus, Mailcode 6401
Professor
Faculty, TEMPE Campus, Mailcode 6401
Professor
Faculty, TEMPE Campus, Mailcode 3251
Professor
Faculty, DTPHX Campus, Mailcode 3251
Biography

Dr. Karen Anderson is a tumor biologist who studies how the immune system can be harnessed to detect and alter cancer development. For example, cancer causes the body to produce specific antibodies, which she and her research team can use as biomarkers to detect cancer in early stages of its growth. They use the alterations in immune response to develop new biomarkers for breast, ovarian, pancreatic and HPV-related cancers.

Dr. Anderson and her collaborators use molecular techniques, such as in vitro protein arrays, next-gen sequencing, and high-throughput functional genomics, to study early alterations in cancer development. They examine the abnormal characteristics of cancer to identify novel targets for cancer treatment and vaccine development.

Research Interests

The Anderson laboratory is focused on understanding how the immune response can be used to detect and alter cancer development. To create an effective cancer immunotherapy, Dr. Anderson’s team identifies target antigens for vaccine development, and understanding of the mechanisms of immune regulation that limit effective immunotherapy. The lab uses proteomic tools to perform immunoprofiling for cancer and infectious disease detection and monitoring.

Publications
  • Chowell D, Castillo-Chavez C, Krishna S, Qiu X, Anderson KS. Modelling the effect of early detection of Ebola. Lancet Infectious Diseases (2015).
  • Anderson KS, Cramer DW, Sibani S, Wallstrom G, Wong J, Park J, Qiu J, Vitonis A, LaBaer J. An Autoantibody signature for the serologic detection of ovarian cancer. Journal Proteome Research (2014).
  • D'Souza G, Gross N, Pai SI, Haddad R, Anderson KS, Rajan S, Gerber J, Gillison ML, Posner MR. Oral human papillomavirus (HPV) infection in HPV-positive oropharyngeal cancer cases and their partners. Journal of Clinical Oncology (2014).
  • Marks JR, Anderson KS, Engstrom P, Godwin AK, Esserman LJ, Longton G, Iverson ES, Mathew A, Patriotis C, Pepe MS. Construction and Analysis of the NCI-EDRN Breast Cancer Reference Set for Circulating Markers of Disease. Cancer Epidemiol Biomarkers Prev (2014).
  • Zeng W, Su M, Anderson KS, Sasada T. Artificial antigen-presenting cells expressing CD80, CD70 and 4-1BB ligand efficiently expand functional T cells specific to tumor-associated antigens. Immunobiology (2014).
  • Wallstrom G, Anderson KS, LaBaer J. Biomarker Discovery for Heterogeneous Diseases. Cancer Epidemiology, Biomarkers & Prevention (2013).
  • Jaras K and Anderson KS. Autoantibodies in cancer: Prognostic Biomarkers and Immune Activation. (0).
Research Activity
Fall 2017
Course NumberCourse Title
BIO 492Honors Directed Study
MBB 492Honors Directed Study
BIO 493Honors Thesis
MBB 495Undergraduate Research
MIC 495Undergraduate Research
BIO 495Undergraduate Research
BDE 792Research
Summer 2017
Course NumberCourse Title
BDE 792Research
Spring 2017
Course NumberCourse Title
BIO 492Honors Directed Study
MBB 493Honors Thesis
BIO 493Honors Thesis
BIO 494Special Topics
MBB 495Undergraduate Research
BIO 495Undergraduate Research
AML 590Reading and Conference
BIO 598Special Topics
BDE 792Research
Fall 2016
Course NumberCourse Title
BIO 189Life Sciences Career Paths
BIO 492Honors Directed Study
MBB 492Honors Directed Study
BIO 493Honors Thesis
MIC 495Undergraduate Research
MBB 495Undergraduate Research
BDE 792Research
Summer 2016
Course NumberCourse Title
BDE 792Research
Spring 2016
Course NumberCourse Title
MIC 420Immun: Molecular&Cell Foundtns
BIO 420Immun: Molecular&Cell Foundtns
BIO 492Honors Directed Study
BIO 493Honors Thesis
MBB 493Honors Thesis
BIO 495Undergraduate Research
AML 590Reading and Conference
BDE 792Research
Fall 2015
Course NumberCourse Title
BIO 189Life Sciences Career Paths
MBB 492Honors Directed Study
BIO 492Honors Directed Study
MBB 495Undergraduate Research
BDE 792Research
Summer 2015
Course NumberCourse Title
BDE 792Research
Spring 2015
Course NumberCourse Title
MIC 401Research Paper
BIO 493Honors Thesis
BIO 494Special Topics
BIO 495Undergraduate Research
AML 590Reading and Conference
BIO 598Special Topics
BDE 792Research
Fall 2014
Course NumberCourse Title
BIO 492Honors Directed Study
MBB 495Undergraduate Research
BDE 792Research
Summer 2014
Course NumberCourse Title
BDE 792Research
Spring 2014
Course NumberCourse Title
MBB 495Undergraduate Research
BDE 792Research
Fall 2013
Course NumberCourse Title
BIO 189Life Sciences Career Paths
BIO 353Cell Biology
BDE 792Research
Spring 2013
Course NumberCourse Title
BIO 493Honors Thesis
BIO 494Special Topics
MIC 495Undergraduate Research
BIO 495Undergraduate Research
BIO 598Special Topics
Presentations
  • Karen Anderson, M.D., Ph.D. "Programmable protein microarrays for cancer biomarker detection.". UC Riverside Environmental Toxicology Program (Nov 2014).
  • Karen Anderson, M.D., Ph.D. "Molecular Biomarkers for the Early Detection of Cancer". The Third Annual Global Biomarkers Consortium, San Francisco, CA (Oct 2014).
  • Karen Anderson, M.D., Ph.D. "Proteomics for Early Detection of Cancer". Lankenau Institute, Philadelphia, PA (Sep 2014).
  • Karen Anderson, M.D., Ph.D. "Designing Pipelines for Breast Cancer Biomarker Discovery and Validation.". NCI W.W.- Japan Joint Workshop on Biomarkers for Early Cancer Detection, Bethesda, MD (Feb 2014).
  • Karen Anderson, M.D., Ph.D. "Modeling immune regulation of tumor dormancy". NCI Mathmatical Models of Breast Cancer Worksop (Jan 2014).
  • Karen Anderson. Immunotherapy of Breast Cancer: Using Proteomics for Immune Monitoring. Lecture Series - Mayo Clinic Rochester, MN (Aug 2012).
  • Karen Anderson. Mapping the immunome: Using proteomics for cancer detection and prognosis". MCB 701 (Jan 2012).
Honors / Awards

Health Care Heroes Award, Phoenix Business Journal

Most Influential Women in Arizona, Arizona Business Magazine

 

Professional Associations
American Association for Cancer Research American Society of Clinical Oncology
Service
  • Faculty Search Committee, SoLS-Biomarkers, Member (2014 - Present)
  • Womanity 2014 Panel, Presenter, Panel/Presenter (2014 - Present)
  • Mayo Clinic, Educational Lectures, Speaker (2014 - Present)
  • TGen Breast Cancer Retreat, Speaker (2014 - Present)
  • ASU Foundation’s Women & Philanthropy Program, "Detecting Cancer: From Bench to Bedside", Presenter (2013 - Present)
  • Basis Chandler High School, biomarkers to detect cancer at early stages, vaccine development and cancer treatment, guest speaker, (2013 - Present)
  • AZ Science Center - Framing New Pathways to Medical Discovery for Families, Students, and Teachers. New Frontiers in Medical Science, Presentation (2013 - Present)
  • Horizon (PBS) Invited Interview, Collaboration - Making a Difference in Medical Research and Public Health, Interview (2013 - Present)
  • City of Phoenix Women's Commision, Panel (2013 - Present)
  • Executive Committee for the AZ Biomarker Alliance, Member (2012 - Present)
  • Mayo Clinic Cancer Center in Arizona Research Committee, Member (2012 - Present)
  • College of Reviewers, Genome Canada, Large Scale Applied Research Project Competition, Member (2012 - Present)
  • Genome Canada, Large Scale Research Projects Review Committee, Member (2012 - Present)
  • Komen IIR PED & IIR/CCR METIR Peer Review Committee, Member (2012 - Present)
  • NCI Physical Sciences of Oncology, Center Advisory Committee, Member (2012 - Present)
  • Cancer Biomarkers Study Section, Center for Scientific Review, Member (2012 - 2016)
  • NCI Cancer Bioamarkers Study Section Committee, Ad-hoc (2011 - 2016)
  • NCI Cancer Biomarkers Study Section Committee, Standing member (2012 - 2016)
  • DNASU Faculty/Scientific Advisory Committee, SoLS, Member (2014 - 2016)
  • Komen IIR PEd & IIR/CCR Metir Peer Review Committee, Member (2014 - 2014)
  • NCI AIDS associated Opportunistic Infections (AOIC) Review Committee, Ad hoc member (2014 - 2014)
  • NCI Detection of Pathogen associated Cancer committee, Ad hoc committee member (2014 - 2014)
  • Mayo Clinic Cancer Center in Arizona Research Committee, Member (2014 - 2014)
  • Platform Technologies Challenge, Keck Foundation, Reviewer (2013 - 2014)
  • Facilities Committee, Member (2012 - 2013)
  • Faculty Search Committee, School of Life Sciences, Member (2012 - 2013)
  • Women In Stem, Workshop Lean In, Panelist (2013 - 2013)
  • Komen IIR PEd & IIR/CCR Metir Peer Review Committee, Member (2012 - 2013)
  • ASU-NIH Day, Best Practice for WRiting Proposals for NIH, Panelist (2013 - 2013)
  • ASU Faculty Women's Assocation, Panelist (2012 - 2012)
  • NCI Cancer Bioamarkers Study Section Committee, Ad-hoc (2011 - 2012)
  • Breast Cancer Interest Group, Member (2011 - 2012)
  • MCB Graduate School Admissions Committee, Member (2011 - 2012)