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Shaopeng Wang

Research Professor (FSC)
Faculty, TEMPE Campus, Mailcode 5801

Dr. Shaopeng Wang holds a BS in biology and an MS in biophysics from Tsinghua University (Beijing, China). He received Ph.D. in physical chemistry from the University of Miami (Florida) and did a two-year post-doctoral study in the Department of Physics at Florida International University. Before join ASU, Dr. Wang was a senior research scientist at ICx Nomadics, Inc. 

Research Interests

Interested in develop biosensors and bioinstrumentations for biomedical applications. Currently working on Plasmonic-based Electrochemical Impedance Microscopy (P-EIM) and other innovative optical/electrochemical sensing methods for detectiopn of chemicals and biological molecules and real time label-free measurment of molecular interactions and cellular dynamics.

  • Fenni Zhang, Shaopeng Wang*, Linliang Yin, Yunze Yang, Yan Guan, Wei Wang, Han Xu and Nongjian Tao*. Quantification of Epidermal Growth Factor Receptor Expression Level and Binding Kinetics on Cell Surfaces by Surface Plasmon Resonance Imaging. Anal. Chem (2015).
  • Karan Syal, Wei Wang, Xiaonan Shan, Shaopeng Wang, Hong-Yuan Chen, Nongjian Tao. Plasmonic imaging of protein interactions with single bacterial cells. Biosensors and Bioelectronics (2015).
  • Linliang Yin, Shaopeng Wang*, Xiaonan Shan, Shengtao Zhang, Nongjian Tao*. Quantification of protein interaction kinetics in a micro droplet. Review of Scientific Instruments (2015).
  • Linliang Yin, Wei Wang, Shaopeng Wang, Fenni Zhang, Shengtao Zhang, Nongjian Tao. How does fluorescent labeling affect the binding kinetics of proteins with intact cells?. Biosensors and Bioelectronics (2015).
  • Linliang Yin, Yunze Yang, Shaopeng Wang, Wei Wang, Shengtao Zhang, Nongjian Tao. Measuring the binding kinetics of antibody-conjugated gold nanoparticles with intact cells. Small (2015).
  • Xiaonan Shan, Shan Chen, Hui Wang, Zixuan Chen, Yan Guan, Yixian Wang, Shaopeng Wang, Hong-Yuan Chen, Nongjian Tao. Mapping Local Quantum Capacitance and Charged Impurities in Graphene via Plasmonic Impedance Imaging. Advanced Materials (2015).
  • Yan Guan, Xiaonan Shan, Fenni Zhang, Shaopeng Wang, Hong-Yuan Chen, Nongjian Tao. Kinetics of small molecule interactions with membrane proteins in single cells measured with mechanical amplification. Science Advances (2015).
  • Yixian Wang, Xiaonan Shan, Fengjuan Cui, Jinghong Li, Shaopeng Wang, Nongjian Tao. Electrochemical reactions in sub-femtoliter-droplets studied with plasmonics-based electrochemical current microscopy. Analytical Chemistry (2015).
  • Yunze Yang, Hui Yu, Xiaonan Shan, Wei Wang, Xianwei Liu, Shaopeng Wang, and Nongjian Tao. Label-Free Tracking of Single Organelle Transportation in Cells with Nanometer Precision Using a Plasmonic Imaging Technique. Small (2015).
  • Hui Yu, Xiaonan Shan, Shaopeng Wang, Jongyuan Chen and Nongjian Tao. Plasmonic Imaging and Detection of Single DNA Molecules. ACS Nano (2014).
  • Xiaonan Shan, Yimin Fang, Shaopeng Wang, Yan Guan, Jongyuan Chen and Nongjian Tao. Detection of charges and molecules with self-assembled nano-oscillators. Nano Letters (2014).
  • Yan Guan, Xiaonan Shan, Shaopeng Wang, Peiming Zhang, and Nongjian Tao. Detection of molecular binding via charge-induced mechanical response of optical fibers. Chemical Science (2014).
  • Christopher MacGriff, Ly Nguyen, Shaopeng Wang,* Nongjian Tao. Four-port microfluidic flow-cell with instant sample switching. Review of Scientific Instruments (2013).
  • Christopher MacGriff, Shaopeng Wang, Peter Wiktor, Wei Wang, Xiaonan Shan, Nongjian Tao. Charge-based Detection of Small Molecules by Plasmonic-based Electrochemical Impedance Microscopy. Analytical Chemistry (2013).
  • Jin Lu, Wei Wang, Shaopeng Wang, Xiaonan Shan, Jinghong Li, Nongjian Tao. Plasmonic-Based Electrochemical Impedance Spectroscopy: Application to Molecular Binding. Analytical Chemistry (2012).
  • Wang, Wei; Wang, Shaopeng; Liu, Qiang; Wu, Jie; Tao, Nongjian. Mapping Single-Cell–Substrate Interactions by Surface Plasmon Resonance Microscopy. Langmuir (2012).
  • Wei Wang, Yunze Yang, Shaopeng Wang, Vinay J Nagaraj, Qiang Liu, Jie Wu and Nongjian Tao. A label-free method to measure and map binding kinetics of membrane proteins in single living cells. Nature Chemistry (2012).
  • Xiaonan Shan, Ismael Díez-Pérez, Luojia Wang, Peter Wiktor, Ying Gu, Lihua Zhang, Wei Wang, Jin Lu, Shaopeng Wang, Qihuang Gong, Jinghong Li & Nongjian Tao. Imaging the electrocatalytic activity of single nanoparticles. Nature Nanotechnology (2012).
  • Rinosh Joshua Mani, Roman G. Dye, Timothy A. Snider, Shaopeng Wang, Kenneth D. Clinkenbeard. Bi-cell surface plasmon resonance detection of aptamer mediated thrombin capture in serum. Biosensors and Bioelectronics (2011).
  • Shan, Xiaonan; Wang, Shaopeng; Wang, Wei; Tao, Nongjian. Plasmonic-based Imaging of Local Square Wave Voltammetry. Analytical Chemistry (2011).
  • Wei Wang, Kyle Foley, Xiaonan Shan, Shaopeng Wang, Seron Eaton, Vinay J Nagaraj, Peter Wiktor, Urmez Patel, and Nongjian Tao. Single cells and intracellular processes studied by a plasmonic-based electrochemical impedance microscopy. Nature Chemistry (2011).
  • Shaopeng Wang, X. Huang, X. Shan, K. J. Foley, N. J. Tao. Electrochemical Surface Plasmon Resonance: Basic Formalism and Experimental Validation. Analytical Chemistry (2010).
  • Shaopeng Wang, Xiaonan Shan, Urmez Patel, Xinping Huang, Jin Lu, Jinghong Li, Nongjian Tao. Label-free imaging, detection and mass measurement of single viruses by Surface Plasmon Resonance. Proc Natl Acad Sci USA (2010).
  • X. Shan, X. Huang, K. J. Foley, P. Zhang, K. Chen, Shaopeng Wang, and N. J. Tao. Measuring Surface Charge Density and Particle Height Using Surface Plasmon Resonance Technique. Analytical Chemistry (2010).
  • Xiaonan Shan, Shaopeng Wang and Nongjian Tao. Study of single particle charge and Brownian motions with surface plasmon resonance. APPLIED PHYSICS LETTERS (2010).
  • Xiaonan Shan, Urmez Patel, Shaopeng Wang, Rodrigo Iglesias, N. J. Tao. Imaging Local Electrochemical Current Via Surface Plasmon Resonance. Science (2010).
  • Xinping Huang, Shaopeng Wang, Xiaonan Shan, Xijun Chang, Nongjian Tao. Flow-through Electrochemical Surface Plasmon Resonance: Detection of intermediate reaction products. Journal of Electroanalytical Chemistry (2010).
  • Joan E. Nichols, Joaquin Cortiella, Jungwoo Lee, Jean A. Niles, Meghan Cuddihy, Shaopeng Wang, Andrea Cantu, Ron Mlcak, Esther Valdivia, Ryan Yancy, Joseph Bielitzki, Matthew L. McClure, Nicholas A. Kotov. In vitro analog of human bone marrow from 3D scaffolds with biomimetic inverted colloidal crystal geometry. Biomaterials (2009).
  • Shaopeng Wang, A. Ramachandran, S. J. Ja. Integrated Microring-Resonator Biosensors for Monitoring of Cell Adhesion and Growth, and Detection of Toxic Chemicals in Water. Biosensors and Bioelectronics (2009).
  • A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little. A Universal Biosensing Platform Based on Optical Micro-Ring Resonators. Biosensors and Bioelectronics (2008).
  • Wei. Chen, Sarah L. Westcott, Shaopeng Wang, and Yuanfang Liu. Dose dependent x-ray luminescence in MgF2:Eu2+, Mn2+ phosphors. J. Appl. Phys (2008).
  • Y. Liu, W. Chen, S. Wang, A. Joly. Investigation of Water-Soluble X-ray Luminescence Nanoparticles for Photodynamic Activation. Applied Physics Letter (2008).
  • Y. Liu, Y. Zhang, S. Wang, C. Pope, and W. Chen. Optical behaviors of ZnO-porphyrin conjugates and their potential applications for cancer treatment. Applied Physics Letters (2008).
  • Y. Zhang, W. Chen, S. Wang, Y. Liu, L. Liu, C. Pope. Phototoxicity of zinc oxide nanoparticle conjugates in human ovarian cancer NIH: OVCAR-3 cells. J. Biomed. Nanotech (2008).
Research Activity
Spring 2020
Course NumberCourse Title
BDE 792Research
BDE 799Dissertation
Spring 2019
Course NumberCourse Title
BDE 799Dissertation
  • W. Wang, S. Wang, and N. Tao. Electrochemical Impedance Microscopy: A Label-free Technique for Monitoring Individual Cells and Intracellular Processes. American Physics Society 2012 March Meeting, Boston, Massachusetts (Feb 2012).
  • N. J. Tao and S. Wang. Plasmonic-based Electrochemical Impedance Microscopy (P-EIM) for Label-free Cell Based Assay and Small Molecule Detections. Invited talk at Amgen Inc., Thousand Oaks, CA (Nov 2011).
  • X. Shan, W. Wang, S. Wang, K. Foley, and N. Tao. Plasmonic-based Imaging of Local Electrochemical Current and Interfacial Impedance. The 220th Electrochemical Society Meeting, Boston, Massachusetts (Oct 2011).
  • Shaopeng Wang. Novel Applications of Objective-based Surface Plasmon Resonance Microscopy. Invited seminar at Changchun institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, (Apr 2011).
  • NJ Tao, Kyle Foley, Shaopeng Wang, Xiaonan Shan. Surface Impedance Microscopy for Biomedical Applications. 215th ECS Meeting (May 2009).
  • Sun Devils Badminton Club, Faculty Advisor (2015 - Present)
  • Journal of Proteome Research, Reviewer (2013 - Present)
  • Sensors, Reviewer (2013 - Present)
  • Scientific Reports, Reviewer (2013 - Present)
  • Journal of Nano Medicine, Reviewer (2013 - Present)
  • Sensor Letters, Reviewer (2013 - Present)
  • ACS Applied Materials and Interfaces, Reviewer (2012 - Present)
  • Analytical Methods, Reviewer (2012 - Present)
  • Lab on Chip, Reviewer (2012 - Present)
  • Optical Express, Reviewer (2010 - Present)
  • Biodesign Personnel Committee, Member (2010 - Present)
  • PLoS ONE, Reviewer (2009 - Present)
  • Biosensors, lab on chip and engineering technologies (book), Reviewer (2009 - Present)
  • NIH, Grant Proposal Reviewer (2009 - Present)
  • Biosensors and Bioelectronics, Reviewer (2009 - Present)
  • Journal of American Chemical Society, Reviewer (2006 - Present)
  • Journal of nanosciences and nanotechnology, Reviewer (2005 - Present)