Integrated Search Menu

Shaopeng Wang

Research Professor (FSC)
Faculty, TEMPE Campus, Mailcode 5801
Biography: 

Dr. Shaopeng Wang holds a BS in biology and an MS in biophysics from Tsinghua University (Beijing, China). He received Ph.D. in physical chemistry from the University of Miami (Florida) and did a two-year post-doctoral study in the Department of Physics at Florida International University. Before join ASU, Dr. Wang was a senior research scientist at ICx Nomadics, Inc. 

Fax: 
(480)965-9457
Research Interests: 

Interested in develop biosensors and bioinstrumentations for biomedical applications. Currently working on Plasmonic-based Electrochemical Impedance Microscopy (P-EIM) and other innovative optical/electrochemical sensing methods for detectiopn of chemicals and biological molecules and real time label-free measurment of molecular interactions and cellular dynamics.

Publications: 

1.     Fenni Zhang, Shaopeng Wang,* Yunze Yang, Jiapei Jiang, and Nongjian Tao, Imaging Single Bacterial Cells with Electro-optical Impedance Microscopy, ACS Sens., 2020, DOI: 10.1021/acssensors.0c00751, Special Issue: Commemorating NJ Tao.

2.     Wang Y, Yang Y, Chen C, Wang S, Wang H, Jing W, Tao N. One-Step Digital Immunoassay for Rapid and Sensitive Detection of Cardiac Troponin I. ACS Sens. 2020 Apr 24;5(4):1126-1131. doi: 10.1021/acssensors.0c00064. Epub 2020 Mar 30. PubMed PMID: 32180397.

3.     Zhou XL, Yang Y, Wang S, Liu XW. Surface Plasmon Resonance Microscopy: From Single-Molecule Sensing to Single-Cell Imaging. Angew Chem Int Ed Engl. 2020/1/27, 59(5), 1776-1785. DOI: 10.1002/anie.201908806. PubMed PMID: 31531917. NIHMSID: 1068747

4.     Rafael Iriya, Wenwen Jing, Karan Syal, Manni Mo, Chao Chen, Hui Yu, Shelley E Haydel, Shaopeng Wang, Nongjian Tao, Rapid antibiotic susceptibility testing based on bacterial motion patterns with long short-term memory neural networks, IEEE Sensors Journal, vol. 20, no. 9, pp. 4940-4950, May 1, 2020. NIHMS1588088.

5.     G Ma, X Shan, S Wang, N Tao, Quantifying Ligand-Protein Binding Kinetics with Self-Assembled Nano-Oscillators, Anal. Chem. 2019, 91(21), 14149-14156. DOI: 10.1021/acs.analchem.9b04195. PMCID: PMC6995402. 

6.     F Zhang, Y Guan, Y Yang, A Hunt, S Wang, HY Chen, N Tao, Optical tracking of nanometer-scale cellular membrane deformation associated with single vesicle release, 2019, ACS sensors, 4 (8), 2205-2212. DOI: 10.1021/acssensors.9b01201. PMCID: PMC7007815. NIHMSID: 1068592.

7.     W Jing, Y Wang, Y Yang, Y Wang, G Ma, S Wang, N Tao, Time-resolved digital immunoassay for rapid and sensitive quantitation of procalcitonin with plasmonic imaging, 2019, ACS nano 13 (8), 8609-8617. DOI: 10.1021/acsnano.9b02771. PMCID: PMC7008466. NIHMSID: 1068734

8.     M Mo, Y Yang, F Zhang, W Jing, R Iriya, J Popovich, S Wang, T Grys, S. E. Haydel, N. Tao, Rapid Antimicrobial Susceptibility Testing of Patient Urine Samples using Large Volume Free-Solution Light Scattering Microscopy, Analytical chemistry, 2019, 91 (15), 10164-10171. DOI: 10.1021/acs.analchem.9b02174. PMCID: PMC7003966 

9.     Y Yang, X Liu, S Wang, N Tao, Plasmonic imaging of subcellular electromechanical deformation in mammalian cells, Journal of Biomedical Optics, 2019, 24 (6), 066007. PMCID: PMC6586072 DOI: 10.1117/1.JBO.24.6.066007

10.  Guan-Da Syu, Shih-Chin Wang, Guangzhong Ma, Shuang Liu, Donna Pearce, Atish Prakash, Brandon Henson, Lien-Chun Weng, Devlina Ghosh, Pedro Ramos, Daniel Eichinger, Ignacio Pino, Xinzhong Dong, Jie Xiao, Shaopeng Wang, Nongjian Tao, Kwang Sik Kim, Prashant J. Desai & Heng Zhu, Development and application of a high-content virion display human GPCR array, Nature Communications (2019)10:1997. DOI: 10.1038/s41467-019-09938-9

11.  Guangzhong Ma, Hao Zhu, Zijian Wan, Yunze Yang, Shaopeng Wang, Nongjian Tao, Optical imaging of single protein size, charge, mobility, binding and conformational change, bioRxiv, 2019/1/1, p505404.

12.  Ma, Guangzhong; Syu, Guan-Da; Shan, Xiaonan; Henson, Brandon; Wang, Shaopeng; Desai, Prashant; Zhu, Heng; Tao, Nongjian, Measuring ligand binding kinetics to membrane proteins using virion nano-oscillators, J. Am. Chem. Soc., 2018, Sep 12;140(36): 11495 - 11501. doi: 10.1021/jacs.8b07461. PubMed PMID: 30114365. NIHMSID: 994023

13.  Hui Yu, Wenwen Jing, Rafael Iriya, Yunze Yang, Karan Syal, Manni Mo, Thomas E Grys, Shelley E Haydel, Shaopeng Wang, Nongjian Tao, Phenotypic antimicrobial susceptibility testing with deep learning video microscopy, Anal. Chem., 2018, 90 (10), pp 6314–6322, DOI: 10.1021/acs.analchem.8b01128

14.  Y. Yang, X.W. Liu, H. Wang, H. Yu, Y. Guan, S. Wang, and N. Tao, Imaging Action Potential in Single Mammalian Neurons by Tracking the Accompanying Sub-Nanometer Mechanical Motion, ACS Nano, 2018, 12, 4186-4193. DOI: 10.1021/acsnano.8b0086723, PMCID: PMC6141446. Preprint deposited in: https://www.biorxiv.org/content/early/2017/07/25/168054

15.  Yu H, Yang Y, Yang Y, Zhang F, Wang S, Tao N. Tracking fast cellular membrane dynamics with sub-nm accuracy in the normal direction. Nanoscale. 2018 Feb 28. doi: 10.1039/c7nr09483c. PubMed PMID: 29488990. PMCIF: PMC5854544.

16.  Fenni Zhang, Wenwen Jing, Ashley Hunt, Hui Yu, Yunze Yang, Shaopeng Wang, Hong-Yuan Chen, and Nongjian Tao, Label-Free Quantification of Small Molecule Binding to Membrane Proteins on Single Cells by Tracking Nanometer-Scale Cellular Membrane Deformation, ACS Nano, 2018, DOI: 10.1021/acsnano.8b00235. PubMed PMID: 29397682, PMCID: PMC5851003.

17.  Iriya R, Syal K, Jing W, Mo M, Yu H, Haydel SE, Wang S, Tao N. Real-time detection of antibiotic activity by measuring nanometer-scale bacterial deformation. J Biomed Opt. 2017 Dec;22(12):1-9. doi: 10.1117/1.JBO.22.12.126002. PubMed PMID: 29235272.

18.  Syal, Karan; Shen, Simon; Yang, Yunze; Wang, Shaopeng; Haydel, Shelley; Tao, Nongjian, Rapid antibiotic susceptibility testing of uropathogenic E. coli by tracking sub-micron scale motion of single bacterial cells, 2017, ACS Sensors, 2017, 2 (8), pp 1231–1239. DOI: 10.1021/acssensors.7b00392

19.  Liu, X.-W., Yang, Y., Wang, W., Wang, S., Gao, M., Wu, J. and Tao, N. Plasmonic-Based Electrochemical Impedance Imaging of Electrical Activities in Single Cells. 2017, Angew. Chem. Int. Ed.. 56, 8855, doi:10.1002/anie.201703033, PubMed PMID: 28504338, PMCID: PMC5837822.

20.  H Yu, X Shan, S Wang, N Tao, Achieving high spatial resolution surface plasmon resonance microscopy with image reconstruction, Anal. Chem., 2017, 89 (5), pp 2704–2707. DOI: 10.1021/acs.analchem.6b05049.

21.  Y Wang, X Shan, H Wang, S Wang, N Tao, Plasmonic imaging of surface electrochemical reactions of single gold nanowires, J. Am. Chem. Soc., 2017, 139 (4), pp 1376–1379. DOI: 10.1021/jacs.6b10693.

22.  K Syal, M Mo, H Yu, R Iriya, W Jing, G Sui, S Wang, TE Grys, SE Haydel, N Tao, Current and emerging techniques for antibiotic susceptibility tests, Theranostics 2017, 7 (7), 1795-1805

23.  Jin Lu, Yunze Yang, Wei Wang, Jinghong Li, Nongjian Tao*, Shaopeng Wang*, Label-free imaging of histamine mediated G protein-coupled receptors activation in live cells, Anal. Chem. 2016, 88, 11498−11503. DOI: 10.1021/acs.analchem.6b02677. PMCID# PMC5144837 (Open access)

24.  Guangzhong Ma, Yan Guan, Shaopeng Wang*, Han Xu*, and Nongjian Tao*, Study Small Molecule-Membrane Protein Binding Kinetics with Nanodisc and Charge Sensitive Optical Detection, Anal. Chem. 2016, 88, 2375-2379, DOI: 10.1021/acs.analchem.5b04366. NIHMS836629, PubMed # 26752355

25.  Yixian Wang, Xiaonan Shan, Shaopeng Wang, and Nongjian Tao, Imaging Local Electric Field Distribution by Plasmonic Impedance Microscopy, Anal. Chem. 2016, 88, 1547-1552, DOI: 10.1021/acs.analchem.5b04382

26.  Karan Syal, Rafael Iriya, Yunze Yang, Hui Yu, Shaopeng Wang, Shelley E Haydel, Hong-Yuan Chen, and Nongjian Tao, Antimicrobial Susceptibility Test with Plasmonic Imaging and Tracking of Single Bacterial Motions on Nanometer Scale, ACS Nano, 2016, 10(1), 845-852. DOI: 10.1021/acsnano.5b05944

27.  Zixuan Chen, Xiaonan Shan, Yan Guan, Shaopeng Wang, Jun-Jie Zhu, and Nongjian Tao, Imaging Local Heating and Thermal Diffusion of Nanomaterials with Plasmonic Thermal Microscopy, ACS Nano, 2015, 9 (12), pp 11574–11581 DOI: 10.1021/acsnano.5b05306

28.  Simon Shen, Karan Syal, Nongjian Tao* and Shaopeng Wang*, Note: An automated image analysis method for high-throughput classification of surface-bound bacterial cell motions, Review of Scientific Instrument, 2015, 86, 126104. DOI: 10.1063/1.4937479

29.  Linliang Yin, Shaopeng Wang*, Xiaonan Shan, Shengtao Zhang, Nongjian Tao*, Quantification of protein interaction kinetics in a micro droplet, Review of Scientific Instruments, 2015, 86, 114101. DOI: 10.1063/1.4934802. PMCID: PMC4636506. (RSI editor’s Picks, Featured Article, Cover Article)

30.  Xiaonan Shan, Shan Chen, Hui Wang, Zixuan Chen, Yan Guan, Yixian Wang, Shaopeng Wang, Hong-Yuan Chen, Nongjian Tao, Mapping Local Quantum Capacitance and Charged Impurities in Graphene via Plasmonic Impedance Imaging, Advanced Materials, 2015, 27(40), 6213-6219, DOI: 10.1002/adma.201502822

31.  Yan Guan, Xiaonan Shan, Fenni Zhang, Shaopeng Wang, Hong-Yuan Chen, Nongjian Tao, Kinetics of small molecule interactions with membrane proteins in single cells measured with mechanical amplification, Science Advances, 2015, 1, e1500633. DOI: 10.1126/sciadv.1500633

32.  Fenni Zhang, Shaopeng Wang*, Linliang Yin, Yunze Yang, Yan Guan, Wei Wang, Han Xu and Nongjian Tao*, Quantification of Epidermal Growth Factor Receptor Expression Level and Binding Kinetics on Cell Surfaces by Surface Plasmon Resonance Imaging, Anal. Chem. 2015, 87 (19), 9960-9965. DOI: 10.1021/acs.analchem.5b02572. PMID: 26368334, NIHMSID 777521, PMCID: PMC4836855

33.  Linliang Yin, Yunze Yang, Shaopeng Wang, Wei Wang, Shengtao Zhang, Nongjian Tao, Measuring the binding kinetics of antibody-conjugated gold nanoparticles with intact cells, Small, 11(31), 3782-3788. Doi:10.1002/smll.201500112. PMCID: PMC4552349. PMID: 25865036

34.  Yunze Yang,  Hui Yu,  Xiaonan Shan, Wei Wang, Xianwei Liu, Shaopeng Wang, and Nongjian Tao, Label-Free Tracking of Single Organelle Transportation in Cells with Nanometer Precision Using a Plasmonic Imaging Technique, Small11(24), 2878-2884, 2015, DOI: 10.1002/smll.201403016. PMCID: PMC4474744

35.  Linliang Yin, Wei Wang, Shaopeng Wang, Fenni Zhang, Shengtao Zhang, Nongjian Tao, How does fluorescent labeling affect the binding kinetics of proteins with intact cells? Biosensors and Bioelectronics, 2015, 66, 412-416. DOI: 10.1016/j.bios.2014.11.036. PMID: 25486538. NIHMSID 647485, PMCID: PMC4836836.

36.  Karan Syal, Wei Wang, Xiaonan Shan, Shaopeng Wang, Hong-Yuan Chen, Nongjian Tao, Plasmonic imaging of protein interactions with single bacterial cells, Biosens. Bioelectron., 2015, 63, 131-137. DOI: 10.1016/j.bios.2014.06.069.

37.  Yixian Wang, Xiaonan Shan, Fengjuan Cui, Jinghong Li, Shaopeng Wang, Nongjian Tao, Electrochemical reactions in sub-femtoliter-droplets studied with plasmonics-based electrochemical current microscopy, Analytical Chemistry, 2015, 87(1), 494-498, DOI: 10.1021/ac5036692.

38.  Wei Wang, Linliang Yin, Laura Gonzalez-Malerva, Shaopeng Wang, Xiaobo Yu, Seron Eaton, Shengtao Zhang, Hong-Yuan Chen, Joshua LaBaer, Nongjian Tao, In situ drug-receptor binding kinetics in single cells: a quantitative label-free study of anti-tumor drug resistance, Scientific Reports, 2014, 4, doi:10.1038/srep06609. PMCID: PMC4196117

39.  Wenbin Liang, Shaopeng Wang*, Fernanda Festa, Peter Wiktor, Wei Wang, Mitchell Magee‖, Joshua LaBaer*, Nongjian Tao*, Measure Small Molecule Binding Kinetics on Protein Microarray by Plasmonic-based Electrochemical Impedance Imaging, Analytical Chemistry, 2014, 86 (19), 9860–9865. DOI: 10.1021/ac5024556, PMCID# PMC4188269.

40.  Hui Yu, Xiaonan Shan, Shaopeng Wang, Hong-Yuan Chen, Nongjian Tao, Molecular scale origin of surface plasmon resonance biosensors, Analytical Chemistry, 2014, 86 (18), 8992-8997. DOI: 10.1021/ac501363z

41.  Xiaonan Shan, Yimin Fang, Shaopeng Wang, Yan Guan, Jongyuan Chen and Nongjian Tao, Detection of charges and molecules with self-assembled nano-oscillators, Nano Lett., 2014, 14 (7), 4151–4157. DOI: 10.1021/nl501805e.

42.  Hui Yu, Xiaonan Shan, Shaopeng Wang, Jongyuan Chen and Nongjian Tao, Plasmonic Imaging and Detection of Single DNA Molecules, ACS Nano, 2014, (4), 3427–3433. DOI: 10.1021/nn4062885. http://pubs.acs.org/doi/abs/10.1021/nn4062885

43.  Yan Guan, Xiaonan Shan, Shaopeng Wang, Peiming Zhang, and Nongjian Tao, Detection of molecular binding via charge-induced mechanical response of optical fibers, Chemical Science, 2014, (11), 4375-4381. DOI: 10.1039/C4SC01188K. NIHMSID 836629

44.  Christopher MacGriff, Ly Nguyen, Shaopeng Wang,* Nongjian Tao, Note: Four-port microfluidic flow-cell with instant sample switching, Review of Scientific Instruments, 2013, 84(10), 106110. DOI: 10.1063/1.4826359. PMCID: PMC4108724. 

45.  Christopher MacGriff, Shaopeng Wang*, Peter Wiktor, Wei Wang, Xiaonan Shan, Nongjian Tao, Charge-based Detection of Small Molecules by Plasmonic-based Electrochemical Impedance Microscopy, Analytical Chemistry85 (14), 6682–6687, 2013. DOI: 10.1021/ac400475z. 

46.  Xiaonan Shan, Ismael Díez-Pérez, Luojia Wang, Peter Wiktor, Ying Gu, Lihua Zhang, Wei Wang, Jin Lu, Shaopeng Wang, Qihuang Gong, Jinghong Li & Nongjian Tao, Imaging the electrocatalytic activity of single nanoparticles, Nature Nanotechnology, 2012, 7, 668–672. doi:10.1038/nnano.2012.134.

47.  Wei Wang, Yunze Yang, Shaopeng Wang, Vinay J Nagaraj, Qiang Liu, Jie Wu and Nongjian Tao, Label-free measuring and mapping of binding kinetics of membrane proteins in single living cells, Nature Chemistry, 2012, 4(10), 846-53. DOI:10.1038/nchem.1434. (PMC # 3660014 NIHMSID # 468566)

48.  Wang, Wei; Wang, Shaopeng; Liu, Qiang; Wu, Jie; Tao, Nongjian, Mapping Single-Cell–Substrate Interactions by Surface Plasmon Resonance Microscopy, Langmuir, 2012, 28(37), 13373-13379, DOI: 10.1021/la301712h, PMCID: PMC3660850.

49.  Jin Lu, Wei Wang, Shaopeng Wang, Xiaonan Shan, Jinghong Li, Nongjian Tao, "Plasmonic-Based Electrochemical Impedance Spectroscopy: Application to Molecular Binding" Analytical Chemistry, Anal. Chem., 2012, 84 (1), pp 327–333, DOI: 10.1021/ac202634h, NIHMSID: 344470. PMCID: PMC3299414.

50.  Shan, Xiaonan; Wang, Shaopeng; Wang, Wei; Tao, Nongjian, Plasmonic-based Imaging of Local Square Wave Voltammetry, Analytical Chemistry, Anal. Chem., 2011, 83 (19), pp 7394–7399, DOI: 10.1021/ac201392r, PMCID: PMC3288114.

51.  Rinosh Joshua Mani, Roman G. Dye, Timothy A. Snider, Shaopeng Wang, Kenneth D. Clinkenbeard, bi-cell surface plasmon resonance detection of aptamer mediated thrombin capture in serum, Biosensors and Bioelectronics, 26 (2011) 4832– 4836. 

52.  Wei Wang, Kyle Foley, Xiaonan Shan, Shaopeng Wang, Seron Eaton, Vinay J Nagaraj, Peter Wiktor, Urmez Patel, and Nongjian Tao, Single cells and intracellular processes studied by a plasmonic-based electrochemical impedance microscopy, Nature Chemistry, 3, 249–255, (2011), doi:10.1038/nchem.961, NIHMSID: NIHMS358337, PMCID: PMC3309525.

53.  Xiaonan Shan, Shaopeng Wang and Nongjian Tao, Study of single particle charge and Brownian motions with surface plasmon resonance, Applied Physic Letters, 97, 223703,  2010, PMCID: 3009754

54.  S. Wang, X. Shan, U. Patel, X. Huang, J. Lu, J. Li, NJ Tao, Label-free imaging, detection and mass measurement of single viruses by Surface Plasmon Resonance, Proc Natl Acad Sci U S A, 2010, 107 (37), 16028-16032, PMCID: 2941305.

55.  X. Shan, U. Patel, S. Wang, R. Iglesias, NJ. Tao, Imaging Local Electrochemical Current Via Surface Plasmon Resonance, Science, 2010, 327, 1363.

56.  S. Wang, X. Huang, X. Shan, K. J. Foley, NJ. Tao, Electrochemical Surface Plasmon Resonance: Basic Formalism and Experimental Validation, Analytical Chemistry, 2010, 82(3), 935-941. DOI: 10.1021/ac902178f

57.  X. Huang, S. Wang, X. Shan, X. Chang, NJ Tao, Flow-through Electrochemical Surface Plasmon Resonance: Detection of intermediate reaction products, Journal of Electroanalytical Chemistry 649 (2010) 37–41, DOI:10.1016/j.jelechem.2009.12.027

58.  X. Shan, X. Huang, K. J. Foley, P. Zhang, K. Chen, S. Wang, and NJ. Tao, Measuring Surface Charge Density and Particle Height Using Surface Plasmon Resonance Technique, Analytical Chemistry, 2010, 82(1), 234-240. DOI: 10.1021/ac901816z

59.  S. Wang,* A. Ramachandran, S. J. Ja, Integrated Microring-Resonator Biosensors for Monitoring of Cell Growth and Detection of Toxic Chemicals in Water, Biosensors and Bioelectronics, 2009, 24, 3061–3066. DOI: 10.1016/j.bios.2009.03.027.

60.  J. E. Nichols, J. Cortiella, J. Lee, J. A. Niles, M. Cuddihy, S. Wang, A. Cantu, R. Mlcak, E. Valdivia, R. Yancy, J. Bielitzki, M. L. McClure, N. A. Kotov. In vitro analog of human bone marrow from 3D scaffolds with biomimetic inverted colloidal crystal geometry, Biomaterials, 30 (6), p.1071-1079, Feb 2009.

61.  A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, A Universal Biosensing Platform Based on Optical Micro-Ring Resonators, Biosensors and Bioelectronics, 2008, 23, 939–944. DOI:10.1016/j.bios.2007.09.007.

62.  W. Chen, S. L. Westcott, S. Wang, and Y. Liu, Dose dependent x-ray luminescence in MgF2:Eu2+, Mn2+ phosphors, J. Appl. Phys. 103, 113103 (2008); DOI:10.1063/1.2937084.

63.  Y. Zhang, W. Chen, S. Wang, Y. Liu, L. Liu, C. Pope. Phototoxicity of zinc oxide nanoparticle conjugates in human ovarian cancer NIH: OVCAR-3 cells. J. Biomed. Nanotech. 2008, 4, 432-438.

64.  Y. Liu, W. Chen, S. Wang, A. Joly, S. Westcott, and B. Woo, X-ray Luminescence of LaF3:Tb and LaF3:Ce,Tb Water Soluble Nanoparticles, Journal of Applied Physics, 2008, 103, 063105. DOI: 10.1063/1.2890148.

65.  Y. Liu, Y. Zhang, S. Wang, C. Pope, and W. Chen, Optical behaviors of ZnO-porphyrin conjugates and their potential applications for cancer treatment, Applied Physics Letters, 2008, 92, 143901. DOI: 10.1063/1.2908211.

66.  Y. Liu, W. Chen, S. Wang, A. Joly, Investigation of Water-Soluble X-ray Luminescence Nanoparticles for Photodynamic Activation, Applied Physics Letter, 2008, 92, 043901. 
Note: This article was selected for the February 11, 2008 issue of Virtual Journal of Nanoscale Science & Technology (http://www.vjnano.org), and for the February 1, 2008 issue of Virtual Journal of Biological Physics Research (http://www.vjbio.org).

67.  Y. Liu, S. Wang, J. Krouse, N. A. Kotov, M. Eghtedari, G. Vargas, and M. Motamedi, Rapid Aqueous Photo-polymerization Route to Polymer and Polymer-composite Hydrogel 3D Inverted Colloidal Crystal Scaffolds, Journal of Biomedical Materials Research: part A, 2007, DOI: 10.1002/jbm.a.31199.

68.  Y. Liu and S. Wang,* 3D Inverted Opal Hydrogel Scaffolds with Oxygen Sensing Capability, Colloids and Surfaces B: Biointerfaces, 2007, 58(1), 8-13.

69.  S. Wang,* E. S. Forzani, NJ. Tao, Detection of Heavy Metal Ions in Water by High Resolution Surface Plasmon Resonance Spectroscopy Combined with Anodic Stripping Voltammetry, Analytical Chemistry, 2007, 79(12), 4427-4432, DOI: 10.1021/ac0621773.

70.  A. G. Joly, W. Chen, J. Zhang, and S. Wang, Electronic Energy Relaxation and Luminescence Decay Dynamics of Eu3+ in Zn2SiO4:Eu3+ Phosphors, Journal of Luminescence, 2007, 126, 491–496.

71.  F. Su, B. Ma, K. Ding, G. Lia, S. Wang, W. Chen, A. G. Joly, and D. E. McCready, Luminescence Temperature and Pressure Studies of Zn2SiO4 Phosphors doped with Mn2+ and Eu3+ ions, Journal of Luminescence, 2006, 116, 117–126.

72.  S. Sachin, S. Wang, and N. A. Kotov, Cell Distribution Profiles in Three-Dimensional Scaffolds with Inverted Colloidal Crystal Geometry: Modeling and Experimental Investigations, Small, 2005, 1(12), 1208-1214.

73.  W. Chen, J.-O. Bovin, S. Wang, A. G. Joly, Y. Wang, and P. M. A. Sherwood, Fabrication and Luminescence of ZnS:Mn2+Nanoflowers, Journal of Nanoscience and Nanotechnology, 2005, 5, 1-14.

74.  W. Chen, S. Wang, S. L. Westcott, J. Zhang, K. Dou, A. G. Joly, and D. E. McCready, Structure and Luminescence of BaFBr:Eu(2+) and BaFBr:Eu(2+), Tb(3+) Phosphors and Thin Films, Journal of Applied Physics, 2005, 97, 083506-083514.

75.  Y. Liu, S. Wang, and N. A. Kotov, A Floating Self-Assembly Route to Colloidal Crystal Templates for 3D Cell Scaffolds, Chemistry of Materials, 2005, 17(20); 4918-4924 (DOI: 10.1021/cm048050g).

76.  Y. Zhang, S. Wang, M. Eghtedari, M. Motamedi and N. A. Kotov, Inverted Colloidal Crytal Hydrogel Matrices as Three-Dimensional (3D) Cell Scaffolds, Advanced Functional Materials, 2005, 15, 728-731.

77.  N. A. Kotov, Y. Liu, S. Wang, C. Cumming, M. Eghtedari, G. Vargas, M. Motamedi, J. Nichols, J. Cortiella, Inverted Colloidal Crytals as 3D Cell Scaffolds, Langmuir, 2004, 2019, 7887 - 7892 (DOI: 10.1021/la049958o, cover article).

78.  W. Chen, J-O. Bovin, A. G. Joly, S. Wang, F. Su and G. Li, Full-Color from In2S3 and In2S3:Eu3+ Nanoparticles, Journal of Physical Chemistry B, 2004; 108; 11927-11934.

79.  W. Chen, A. G. Joly, J-O. Malm, J.-O. Bovin, and S. Wang, Full-Color Emission and Temperature Dependence of the Luminescence in Poly-P-phenylene ethynylene-ZnS/Mn2+ Composite Particles, Journal of Physical Chemistry B, 2003, 107(27), 6544-6551.

80.  S. Wang, S. Westcott, and W. Chen, Nanoparticle Luminescence Thermometry, Journal of Physical Chemistry B, 2002, 106, 11203-11209.

81.  S. Wang, N. Mamedova, N. A. Kotov, W. Chen, and J. Studer, Antigen/Antibody Immunocomplex from CdTe Nanoparticle Bioconjugates, Nano Letter, 2002, 2(8), 817-822. Cited 600+.

82.  S. Wang, S. Boussaad, and N. J. Tao, Surface Plasmon Resonance Enhanced Absorption Spectroscopy, Review of Scientific Instruments, 2001, 72, 3055-3060.

83.  S. Wang, S. Boussaad, S. Wong, and N. J. Tao, High-sensitivity Stark Spectroscopy of Organic dsorbates Based on Detection of Surface Plasmon Resonance, Analytical Chemistry, 2000, 72, 4003-4008.

84.  S. Wang, Q. Zhang, P. K. Datta, R. E. Gawley, and R. M. Leblanc, Amphiphilic Anthracyl Crown Ether – a Langmuir and Langmuir-Schaefer Films Study, Langmuir, 2000, 16(10), 4607-4612.

85.  S. Wang, R. Lunn, M. P. Krafft, and R. M. Leblanc, One and a Half Layer? Mixed Langmuir Monolayer of 10,12-pentacosadiynoic Acid and a Semi-fluorinated Tetracosane, Langmuir, 2000, 16(6); 2882-2886.

86.  S. Wang and R. M. Leblanc, Molecular Recognition of Concanavalin A on Mannoside Lipid Monolayer at Air/Water Interface, Biochimica et Biophysica Acta - Biomembranes, 1999, 1419, 307-312. 

87.  Q. Huo, S. Wang, A. Pisseloup, D. Verma, and R. M. Leblanc, Unusual Chromatic Properties Observed from Polymerized Dipeptide Diacetylenes, Chemical Communications, 1999, 1601-1602. 

88.  S. Wang, J. Ramirez, P. G. Wang, and R. M. Leblanc, Surface Chemistry, Topography and Spectroscopy of Mixed-monolayer of 10,12-pentacosadiynoic Acid and its Mannoside Derivative at the Air-water Interface, Langmuir, 1999, 15, 5623-5629. 

89.  R. E. Gawley, Q. Zhang, P. I. Higgs, S. Wang, and R. M. Leblanc, Anthracylmythyl Crown Ethers as Fluorescence Sensors of Saxitoxin, Tetrahedron Letters, 1999, 5461-5464. Corrigendum, p6135.

90.  S. Wang, S. Vidon, and R. M. Leblanc, Chemical and Photochemical Dual Polymerization in a Mixed Langmuir Monolayer of Diacetylene Derivatives and Octadecyltrimethoxysilane, Journal of Colloid and Interface Science, 1998, 207, 303-308. 

91.  Y. J. Li; Y. Fan; X. G. Ren; L. G. Zhang; D. P. Jiang; A. D. Lu; S. Wang, and R. M. Leblanc, Synthesis of a Substituted Phthalocyaninato-Polysiloxane and its Langmuir-Blodgett Films, Journal of Porphyrins and Phthalocyanines, 1998, 2, 1-4. 

92.  S. Wang, R. M. Leblanc, F. Arias, and L. Echegoyen, Study of Langmuir Monolayers of Crown-ether C60 Derivatives and their Interaction with Different Subphase Ions, Thin Solid Film, 1998, 327, 141-144. 

93.  F. Cardullo, F. Diederich, L. Echegoyen, T. Habicher, N. Jayaraman, R. M. Leblanc, J. F. Stoddart, and S. Wang, Stable Langmuir and Langmuir-Blodgett films of Fullerene-Glycodendron Conjugates, Langmuir, 1998, 14, 1955-1959. 

94.  L. Dziri, S. Boussaad, S. Wang and R. M. Leblanc, Surface Topography of Acetylcholinesterase in Langmuir and Langmuir-Blodgett Films, The Journal of Physical Chemistry, 1997, 101(34), 6741-6748. 

95.  S. Wang, Y. Li, L. Shao, J. Ramirez, P. G. Wang, and R. M. Leblanc, Excess Free Energies of Interaction between 10,12-pentacosadiynoic Acid (PDA) and its Mannoside Derivative (MPDA). A Mixed-Monolayer Study, Langmuir, 1997, 13, 1677-1681.

96.  S. Wang, R. M. Leblanc, F. Arias, and L. Echegoyen, Surface and Optical Properties of Langmuir and LB films of a Crown-ether C60 Derivative, Langmuir, 1997, 13, 1672-1676. 

97.  Z. Liu, H. Qin, C. Xiao, C. Wen, S. Wang, and S. Sui, Specific Binding of Avidin to Biotin Containing Lipid Lamella Surfaces Studied with Monolayers and Liposomes. European Biophysics Journal, 1995, 24, 31-38. 

98.  S. Wang and S. Sui, In Situ Observation of Lipid Monolayers at Air/Water Interface by Micro-Fluorescence Film Balance, Progress in Natural Science 《自然科学进展》, 1994, 4(4), 410-416.

99.  S. Wang, C. Wen and S. Sui, Influence of Flexibility of Receptors on Specific Binding of Avidin onto Lipid Membrane, Progress in Natural Science 《自然科学进展》, 1994, 4(3), 375-380.

100.Z. Liu, S. Wang, C. Wen, and S. Sui, Interaction between Avidin and Membrane Bond Model Receptor, Science in China《中国科学》Series B, Chemistry, Life Sciences & Earth Sciences, 1994, 24(11), 1162-1170.

101.S. Wang and S. Sui, Interaction of Vesicles with Phospholipid Monolayer, Acta Biophysica Sinica 《生物物理学报》, 1992, 8(1), 148-153. 

102.S. Sui and S. Wang, Fusion of Phospholipid Vesicles with Langmuir Lipid Monolayer, Thin Solid Films, 1992, 210, 57-59. 

103.S. Sui, H. Wu, and S. Wang, Langmuir-Blodgett FilmBalance, Experimental Technique and Management《实验技术与管理》, 1991, 8(5), 28-31. 

104.S. Wang and S. Sui, Study on the Properties of Cholesterol-Containing Phospholipid Monolayers (LB Film), Acta Biophysica Sinica《生物物理学报》, 1991, 7(3), 328-334. 

105.S. Sui and S. Wang, Langmuir-Blodgett Film and its Application in Biology (review), Progress in Biological Engineering《生物工程进展》, 1991, 11(1), 1-10. 

Research Activity: 

Current Research Projects

  1. Shaopeng Wang,* A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics, NIH NCI IMAT R33CA235294 03/01/2020 - 02/28/2023
  2. Shaopeng Wang,* Direct quantification of binding kinetics between phage and mRNA displayed peptide, Genentech Inc. AGR 11/05/18, 10/30/2018 – 10/29/2020
  3. Nongjian Tao,* Shaopeng Wang, Nano-Oscillator Arrays for Sensitive Plasmonic Detection of Molecular Interaction, Biosensing USA, BIG126720 (VIA NIH NIGMS R44GM126720), 5/1/2018 - 10/31/2020
  4. Shaopeng Wang,* Nongjian Tao, Quantitative label-free imaging of electrical activities in cells, NIH NIGMS 2R01GM107165, 09/01/2018-08/31/2022
  5. Shaopeng Wang,* Shelley Haydel, Point-of-care antimicrobial susceptibility testing based on simultaneous tracking of multi-phenotypic features of single bacterial cells, NIH NIAID 1R01AI138993-01 07/25/2018 - 06/30/2023
  6. Shaopeng Wang,* Measuring small molecule interactions with membrane proteins on single cells via detecting nanometer scale membrane deformations, NIH NIGMS 1R01GM124335-01 07/01/2017 - 06/31/2021
  7. Nongjian Tao,* Shaopeng Wang, Charge sensitive optical detection for high-throughput study of small molecules. NIH NCI IMAT R33CA202834 08/01/2016 - 07/31/2020
  8. Shaopeng Wang,* Nongjian Tao, An Integrated Microarray Printing and Detection System, Biosensing USA, (Via NIH NIGMS 1R44GM114951-01), 4/1/2015-3/31/2020

Completed Research Projects

  1. Shaopeng Wang,* Nongjian Tao, Quantitative label-free imaging of membrane protein interaction kinetics on cells, NIH NIGMS 1R01GM107165, 07/01/2014-06/30/2018    
  2. Nongjian Tao,* Shaopeng Wang, Label-free imaging and tracking of single protein-protein interaction, Moore Foundation, 04/12/2013-07/31/2016
  3. Nongjian Tao*, Shaopeng Wang, Electrochemically-Enhanced Plasmonic Imaging for Quantitative Proteomics, Biosensing USA (Via NIH NIGMS 1R44GM106579), 04/01/2013-03/31/2017
  4. Nongjian Tao,* Shaopeng Wang, Charge sensitive optical detection for high-throughput study of small molecules, NIH NCI IMAT R21CA173205, 09/01/2012 - 08/31/2015
  5. Nongjian Tao,* Shaopeng Wang, IDBR:  Plasmonic-based electrochemical impedance microscopy for studying molecular binding and cellular processes NSF #1151005, 02/01/2012 – 01/31/2016
  6. Nongjian Tao,* Shaopeng Wang, A Self-Assembled Nanomechanical System (NMES) for Molecular Detections, W. M. Keck Foundation,  07/01/2011-06/30/2016
  7. Shaopeng Wang,* Evaluate P-EIM technology for membrane protein binding affinities measurement, Amgen 2012577119       11/13/12 – 05/12/15         
  8. Nongjian Tao,* Shaopeng Wang, Plasmonic Mapping of Ion Channel Activities in Single Cell, NIH R21 1R21DA033839-01, 04/01/2012 - 03/31/2015
  9. Nongjian Tao,* Shaopeng Wang, Measure Protein Interaction at Scale, Piper Bridge Award (Virginia Piper Foundation), 04/01/2012-06/30/2013
  10. Shaopeng Wang,* Nongjian Tao, A Multi-functional Optical Impedance Microscope for Live Cell Imaging NIH R21 RR026235 (8R21GM103396), 05/15/2010-02/28/2013

* Principal Investigator

Summer 2020
Course NumberCourse Title
BDE 792Research
Spring 2020
Course NumberCourse Title
BDE 792Research
BDE 799Dissertation
Spring 2019
Course NumberCourse Title
BDE 799Dissertation
Presentations: 
  • W. Wang, S. Wang, and N. Tao. Electrochemical Impedance Microscopy: A Label-free Technique for Monitoring Individual Cells and Intracellular Processes. American Physics Society 2012 March Meeting, Boston, Massachusetts (Feb 2012).
  • N. J. Tao and S. Wang. Plasmonic-based Electrochemical Impedance Microscopy (P-EIM) for Label-free Cell Based Assay and Small Molecule Detections. Invited talk at Amgen Inc., Thousand Oaks, CA (Nov 2011).
  • X. Shan, W. Wang, S. Wang, K. Foley, and N. Tao. Plasmonic-based Imaging of Local Electrochemical Current and Interfacial Impedance. The 220th Electrochemical Society Meeting, Boston, Massachusetts (Oct 2011).
  • Shaopeng Wang. Novel Applications of Objective-based Surface Plasmon Resonance Microscopy. Invited seminar at Changchun institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, (Apr 2011).
  • NJ Tao, Kyle Foley, Shaopeng Wang, Xiaonan Shan. Surface Impedance Microscopy for Biomedical Applications. 215th ECS Meeting (May 2009).
Service: 
  • Sun Devils Badminton Club, Faculty Advisor (2015 - Present)
  • Journal of Proteome Research, Reviewer (2013 - Present)
  • Sensors, Reviewer (2013 - Present)
  • Scientific Reports, Reviewer (2013 - Present)
  • Journal of Nano Medicine, Reviewer (2013 - Present)
  • Sensor Letters, Reviewer (2013 - Present)
  • ACS Applied Materials and Interfaces, Reviewer (2012 - Present)
  • Analytical Methods, Reviewer (2012 - Present)
  • Lab on Chip, Reviewer (2012 - Present)
  • Optical Express, Reviewer (2010 - Present)
  • Biodesign Personnel Committee, Member (2010 - Present)
  • PLoS ONE, Reviewer (2009 - Present)
  • Biosensors, lab on chip and engineering technologies (book), Reviewer (2009 - Present)
  • NIH, Grant Proposal Reviewer (2009 - Present)
  • Biosensors and Bioelectronics, Reviewer (2009 - Present)
  • Journal of American Chemical Society, Reviewer (2006 - Present)
  • Journal of nanosciences and nanotechnology, Reviewer (2005 - Present)
Industry Positions: 
  • ICx Nomadics Inc. (now part of FLIR), Stillwater, OK, 2001 –2008, Senior Scientist, Principle Investigator